C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction J Lautenschläger, AD Stephens, G Fusco, F Ströhl, N Curry, ... Nature communications 9 (1), 712, 2018 | 277 | 2018 |
Structural basis of synaptic vesicle assembly promoted by α-synuclein G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, ... Nature communications 7 (1), 12563, 2016 | 243 | 2016 |
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ... Nature communications 11 (1), 2820, 2020 | 112 | 2020 |
The cellular environment affects monomeric α-synuclein structure AD Stephens, M Zacharopoulou, GSK Schierle Trends in biochemical sciences 44 (5), 453-466, 2019 | 73 | 2019 |
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, ... Elife 8, e43059, 2019 | 57 | 2019 |
Different structural conformers of monomeric alpha-synuclein identified after lyophilising and freezing AD Stephens, N Nespovitaya, M Zacharopoulou, CF Kaminski, JJ Phillips, ... Analytical chemistry, 2018 | 39 | 2018 |
Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies J Lautenschläger, S Wagner-Valladolid, AD Stephens, ... Journal of Biological Chemistry 295 (30), 10138-10152, 2020 | 29 | 2020 |
Short hydrogen bonds enhance nonaromatic protein-related fluorescence AD Stephens, MN Qaisrani, MT Ruggiero, G Díaz Mirón, UN Morzan, ... Proceedings of the National Academy of Sciences 118 (21), e2020389118, 2021 | 27 | 2021 |
The role of water in amyloid aggregation kinetics AD Stephens, GSK Schierle Current opinion in structural biology 58, 115-123, 2019 | 27 | 2019 |
Observation of high-temperature macromolecular confinement in lyophilised protein formulations using terahertz spectroscopy TA Shmool, PJ Woodhams, M Leutzsch, AD Stephens, MU Gaimann, ... International journal of pharmaceutics: X 1, 100022, 2019 | 24 | 2019 |
Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements RM Delahay, NJ Croxall, AD Stephens Mobile DNA 9, 1-20, 2018 | 21 | 2018 |
Intracellular Aβ42 aggregation leads to cellular thermogenesis CW Chung, AD Stephens, T Konno, E Ward, E Avezov, CF Kaminski, ... Journal of the American Chemical Society 144 (22), 10034-10041, 2022 | 17 | 2022 |
Purification of recombinant α-Synuclein: a comparison of commonly used protocols A Stephens, D Matak-Vinkovic, A Fernandez-Villegas, ... Biochemistry 59 (48), 4563-4572, 2020 | 17 | 2020 |
Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins KH Jong, YT Azar, L Grisanti, AD Stephens, STE Jones, D Credgington, ... Physical Chemistry Chemical Physics 21 (43), 23931-23942, 2019 | 16 | 2019 |
Decreased water mobility contributes to increased α‐synuclein aggregation AD Stephens, J Kölbel, R Moons, CW Chung, MT Ruggiero, N Mahmoudi, ... Angewandte Chemie International Edition 62 (7), e202212063, 2023 | 11 | 2023 |
Millisecond hydrogen/deuterium-exchange mass spectrometry approach to correlate local structure and aggregation in α-synuclein N Seetaloo, M Zacharopoulou, AD Stephens, GS Kaminski Schierle, ... Analytical Chemistry 94 (48), 16711-16719, 2022 | 11 | 2022 |
Label-free characterisation of amyloids and alpha-Synuclein polymorphs by exploiting their intrinsic fluorescence property CW Chung, AD Stephens, E Ward, Y Feng, MJ Davis, CF Kaminski, ... Analytical Chemistry 94 (13), 5367–5374, 2022 | 10 | 2022 |
Fast Purification of Recombinant Monomeric Amyloid‑β from E. coli and Amyloid-β-mCherry Aggregates from Mammalian Cells A Stephens, M Lu, A Fernandez-Villegas, G Kaminski Schierle ACS Chemical Neuroscience 11, 3204-3213, 2020 | 8 | 2020 |
TE; Credgington, D.; Kaminski Schierle, GS; Hassanali, A. Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins KH Jong, YT Azar, L Grisanti, AD Stephens, S Jones Phys. Chem. Chem. Phys 21 (43), 23931-23942, 2019 | 6 | 2019 |
The role of water mobility in protein misfolding AD Stephens, J Kölbel, R Moons, MT Ruggerio, N Mahmoudi, TA Shmool, ... bioRxiv, 2021.01. 06.425575, 2021 | 5 | 2021 |