Evaluation of rhesus monkey and guinea pig hepatic cytosol fractions as models for human aldehyde oxidase KV Choughule, JT Barr, JP Jones Drug metabolism and disposition 41 (10), 1852-1858, 2013 | 41 | 2013 |
In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase KV Choughule, C Barnaba, CA Joswig-Jones, JP Jones Drug Metabolism and Disposition 42 (8), 1334-1340, 2014 | 35 | 2014 |
Interspecies differences in the metabolism of methotrexate: an insight into the active site differences between human and rabbit aldehyde oxidase KV Choughule, CA Joswig-Jones, JP Jones Biochemical pharmacology 96 (3), 288-295, 2015 | 34 | 2015 |
Inhibition of xanthine oxidase by the aldehyde oxidase inhibitor raloxifene: implications for identifying molybdopterin nitrite reductases ER Weidert, SO Schoenborn, N Cantu-Medellin, KV Choughule, JP Jones, ... Nitric Oxide 37, 41-45, 2014 | 33 | 2014 |
Why do most human liver cytosol preparations lack xanthine oxidase activity? JT Barr, KV Choughule, S Nepal, T Wong, AS Chaudhry, ... Drug metabolism and disposition 42 (4), 695-699, 2014 | 28 | 2014 |
Enzyme kinetics, inhibition, and regioselectivity of aldehyde oxidase JT Barr, K Choughule, JP Jones Enzyme kinetics in drug metabolism: fundamentals and applications, 167-186, 2014 | 22 | 2014 |
Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver KV Choughule, CW Locuson, MWH Coughtrie Xenobiotica 45 (6), 495-502, 2015 | 2 | 2015 |
Enzyme Kinetics, Pharmacokinetics, and Inhibition of Aldehyde Oxidase EM Paragas, K Choughule, JP Jones, JT Barr Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications, 257-284, 2021 | 1 | 2021 |
Evaluation of a pre-constructed relative induction score (RIS) curve for prediction of CYP3A4 induction response in vivo G Zhang, T Ho, RJ Clark, S Trisdale, K Choughule, L Fox, D Ramsden Drug Metabolism and Pharmacokinetics 34 (1), S44-S45, 2019 | | 2019 |
Validation of cocktail enzyme assay in 96-well plated human hepatocytes for CYP1A2, CYP2B6 and CYP3A4 induction studies with LC–MS/MS analysis KV Choughule, T Ho, D Wang, DM Stresser, SK Trisdale, T Creegan, ... Drug Metabolism and Pharmacokinetics 33 (1), S61, 2018 | | 2018 |
Characterisation of the sulfotransferases catalysing the sulfation of xenobiotics and steroids in bovine liver K Choughule University of Dundee, 2011 | | 2011 |