Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non‐Biofilm Cultures, and Mycobacterium tuberculosis AT Garrison, Y Abouelhassan, D Kallifidas, F Bai, M Ukhanova, V Mai, ... Angewandte Chemie 127 (49), 15032-15036, 2015 | 92 | 2015 |
Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a … Y Abouelhassan, AT Garrison, GM Burch, W Wong, VM Norwood IV, ... Bioorganic & Medicinal Chemistry Letters 24 (21), 5076-5080, 2014 | 86 | 2014 |
Structure–activity relationships of a diverse class of halogenated phenazines that targets persistent, antibiotic-tolerant bacterial biofilms and Mycobacterium tuberculosis AT Garrison, Y Abouelhassan, VM Norwood IV, D Kallifidas, F Bai, ... Journal of Medicinal Chemistry 59 (8), 3808-3825, 2016 | 77 | 2016 |
Recent progress in natural-product-inspired programs aimed to address antibiotic resistance and tolerance Y Abouelhassan, AT Garrison, H Yang, A Chávez-Riveros, GM Burch, ... Journal of medicinal chemistry 62 (17), 7618-7642, 2019 | 74 | 2019 |
An efficient Buchwald–Hartwig/reductive cyclization for the scaffold diversification of halogenated phenazines: potent antibacterial targeting, biofilm eradication, and prodrug … AT Garrison, Y Abouelhassan, D Kallifidas, H Tan, YS Kim, S Jin, ... Journal of Medicinal Chemistry 61 (9), 3962-3983, 2018 | 51 | 2018 |
Bromophenazine derivatives with potent inhibition, dispersion and eradication activities against Staphylococcus aureus biofilms AT Garrison, F Bai, Y Abouelhassan, NG Paciaroni, S Jin, RW Huigens III Rsc Advances 5 (2), 1120-1124, 2015 | 51 | 2015 |
A phytochemical–halogenated quinoline combination therapy strategy for the treatment of pathogenic bacteria Y Abouelhassan, AT Garrison, F Bai, VM Norwood IV, MT Nguyen, S Jin, ... ChemMedChem 10 (7), 1157-1162, 2015 | 36 | 2015 |
Eradicating bacterial biofilms with natural products and their inspired analogues that operate through unique mechanisms A T Garrison, R W Huigens III Current topics in medicinal chemistry 17 (17), 1954-1964, 2017 | 31 | 2017 |
Acute Negative Allosteric Modulation of M5 Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with No Effect … RW Gould, BW Gunter, M Bubser, RT Matthews, LB Teal, MG Ragland, ... ACS chemical neuroscience 10 (8), 3740-3750, 2019 | 29 | 2019 |
Pyrazine and phenazine heterocycles: platforms for total synthesis and drug discovery RW Huigens III, BR Brummel, S Tenneti, AT Garrison, T Xiao Molecules 27 (3), 1112, 2022 | 27 | 2022 |
Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and … AT Garrison, Y Abouelhassan, H Yang, HH Yousaf, TJ Nguyen, ... MedChemComm 8 (4), 720-724, 2017 | 26 | 2017 |
The Muscarinic Acetylcholine Receptor M5: Therapeutic Implications and Allosteric Modulation AM Bender, AT Garrison, CW Lindsley ACS chemical neuroscience 10 (3), 1025-1034, 2018 | 25 | 2018 |
In vitro antifungal and antibiofilm activities of halogenated quinoline analogues against Candida albicans and Cryptococcus neoformans R Zuo, AT Garrison, A Basak, P Zhang, RW Huigens III, Y Ding International journal of antimicrobial agents 48 (2), 208-211, 2016 | 25 | 2016 |
Recent advances in the synthesis of acridines and phenazines Y Xiao, W Hu, S Sun, JT Yu, J Cheng Synlett 30 (19), 2113-2122, 2019 | 13 | 2019 |
Preparation of 1,5-Dihydropyrazolo[3′,4′:5,6]pyrano[3,4-b]pyridines via a Microwave-Assisted, Palladium-Catalyzed Regioselective C–H Heteroarylation of … AT Garrison, ES Childress, DC Davis, CW Lindsley The Journal of Organic Chemistry 84 (9), 5855-5862, 2019 | 10 | 2019 |
Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the … AT Garrison, DL Orsi, RA Capstick, D Whomble, J Li, TR Carter, AS Felts, ... Journal of Medicinal Chemistry 65 (8), 6273-6286, 2022 | 9 | 2022 |
Palladium-catalyzed oxidative C–H/C–H cross-coupling of pyrazolo [1, 5-a] azines with five-membered heteroarenes TVQ Nguyen, L Poli, AT Garrison Chemical Communications 58 (6), 827-830, 2022 | 6 | 2022 |
Total Synthesis of Hinduchelins A–D, Stereochemical Revision of Hinduchelin A, and Biological Evaluation of Natural and Unnatural Analogues ES Childress, AT Garrison, JR Sheldon, EP Skaar, CW Lindsley The Journal of organic chemistry 84 (10), 6459-6464, 2019 | 6 | 2019 |
Phenazine derivatives as antimicrobial agents RW Huigens III, A Garrison, Y Abouelhassan, H Yang, G Burch US Patent 11,053,205, 2021 | 5 | 2021 |
Abouelhassan Y. Norwood VM Kallifidas D. Bai F. Nguyen MT Rolfe M. Burch GM Jin S. Luesch H. Huigens RW J AT Garrison Med. Chem 59, 3808-3825, 2016 | 5 | 2016 |