| The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril E Tayeb-Fligelman, O Tabachnikov, A Moshe, O Goldshmidt-Tran, ... Science 355 (6327), 831-833, 2017 | 310 | 2017 |
| Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor B Brus, U Kosak, S Turk, A Pislar, N Coquelle, J Kos, J Stojan, JP Colletier, ... Journal of medicinal chemistry 57 (19), 8167-8179, 2014 | 276 | 2014 |
| Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography N Coquelle, M Sliwa, J Woodhouse, G Schirò, V Adam, A Aquila, ... Nature Chemistry 10 (1), 31-37, 2018 | 206 | 2018 |
| Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays MS Lee, R Green, SM Marsillac, N Coquelle, RS Williams, T Yeung, ... Cancer research 70 (12), 4880-4890, 2010 | 183 | 2010 |
| The magic of crystal structure-based inhibitor optimization: development of a butyrylcholinesterase inhibitor with picomolar affinity and in vivo activity U Kosak, B Brus, D Knez, S Zakelj, J Trontelj, A Pislar, R Sink, M Jukic, ... Journal of medicinal chemistry 61 (1), 119-139, 2018 | 150 | 2018 |
| Development of an in-vivo active reversible butyrylcholinesterase inhibitor U Košak, B Brus, D Knez, R Šink, S Žakelj, J Trontelj, A Pišlar, J Šlenc, ... Scientific reports 6 (1), 39495, 2016 | 147 | 2016 |
| Raster-scanning serial protein crystallography using micro-and nano-focused synchrotron beams N Coquelle, AS Brewster, U Kapp, A Shilova, B Weinhausen, ... Acta Crystallographica Section D: Biological Crystallography 71 (5), 1184-1196, 2015 | 143 | 2015 |
| Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments N Coquelle, E Fioravanti, M Weik, F Vellieux, D Madern Journal of Molecular Biology 374 (2), 547-562, 2007 | 143 | 2007 |
| An ERperoxisome tether exerts peroxisome population control in yeast B Knoblach, X Sun, N Coquelle, A Fagarasanu, RL Poirier, ... The EMBO journal 32 (18), 2439-2453, 2013 | 141 | 2013 |
| Mechanism and dynamics of fatty acid photodecarboxylase D Sorigué, K Hadjidemetriou, S Blangy, G Gotthard, A Bonvalet, ... Science 372 (6538), eabd5687, 2021 | 139 | 2021 |
| De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure JP Colletier, MR Sawaya, M Gingery, JA Rodriguez, D Cascio, ... Nature 539 (7627), 43-47, 2016 | 124 | 2016 |
| Radiation damage and dose limits in serial synchrotron crystallography at cryo-and room temperatures E de La Mora, N Coquelle, CS Bury, M Rosenthal, JM Holton, ... Proceedings of the National Academy of Sciences 117 (8), 4142-4151, 2020 | 105 | 2020 |
| Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities D Knez, N Coquelle, A Pišlar, S Žakelj, M Jukič, M Sova, J Mravljak, ... European journal of medicinal chemistry 156, 598-617, 2018 | 86 | 2018 |
| Slow conformational exchange and overall rocking motion in ubiquitin protein crystals V Kurauskas, SA Izmailov, ON Rogacheva, A Hessel, I Ayala, ... Nature communications 8 (1), 145, 2017 | 84 | 2017 |
| Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence S Engilberge, F Riobé, S Di Pietro, L Lassalle, N Coquelle, CA Arnaud, ... Chemical science 8 (9), 5909-5917, 2017 | 77 | 2017 |
| Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy J Woodhouse, G Nass Kovacs, N Coquelle, LM Uriarte, V Adam, ... Nature communications 11 (1), 741, 2020 | 76 | 2020 |
| Observing the overall rocking motion of a protein in a crystal P Ma, Y Xue, N Coquelle, JD Haller, T Yuwen, I Ayala, O Mikhailovskii, ... Nature communications 6 (1), 8361, 2015 | 75 | 2015 |
| N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer’s agents U Košak, D Knez, N Coquelle, B Brus, A Pišlar, F Nachon, X Brazzolotto, ... Bioorganic & medicinal chemistry 25 (2), 633-645, 2017 | 70 | 2017 |
| Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 K Oukoloff, N Coquelle, M Bartolini, M Naldi, R Le Guevel, S Bach, ... European journal of medicinal chemistry 168, 58-77, 2019 | 64 | 2019 |
| Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents D Knez, B Brus, N Coquelle, I Sosič, R Šink, X Brazzolotto, J Mravljak, ... Bioorganic & Medicinal Chemistry 23 (15), 4442-4452, 2015 | 62 | 2015 |
