| Transport characteristics of tramadol in the blood–brain barrier A Kitamura, K Higuchi, T Okura, Y Deguchi Journal of pharmaceutical sciences 103 (10), 3335-3341, 2014 | 59 | 2014 |
| Expression and functional characterization of drug transporters in brain microvascular endothelial cells derived from human induced pluripotent stem cells T Kurosawa, Y Tega, K Higuchi, T Yamaguchi, T Nakakura, T Mochizuki, ... Molecular Pharmaceutics 15 (12), 5546-5555, 2018 | 48 | 2018 |
| Transport of pregabalin via L-type amino acid transporter 1 (SLC7A5) in human brain capillary endothelial cell line Y Takahashi, T Nishimura, K Higuchi, S Noguchi, Y Tega, T Kurosawa, ... Pharmaceutical research 35 (12), 246, 2018 | 46 | 2018 |
| Memantine transport by a proton-coupled organic cation antiporter in hCMEC/D3 cells, an in vitro human blood-brain barrier model K Higuchi, A Kitamura, T Okura, Y Deguchi Drug Metabolism and Pharmacokinetics 30 (2), 182-187, 2015 | 41 | 2015 |
| Prostaglandin transporter OATP2A1/SLCO2A1 is essential for body temperature regulation during fever Y Nakamura, T Nakanishi, H Shimada, J Shimizu, R Aotani, S Maruyama, ... Journal of Neuroscience 38 (24), 5584-5595, 2018 | 34 | 2018 |
| Role of OAT4 in uptake of estriol precursor 16α-hydroxydehydroepiandrosterone sulfate into human placental syncytiotrophoblasts from fetus M Tomi, H Eguchi, M Ozaki, T Tawara, S Nishimura, K Higuchi, ... Endocrinology 156 (7), 2704-2712, 2015 | 31 | 2015 |
| Protective effect of hypotaurine against oxidative stress-induced cytotoxicity in rat placental trophoblasts T Nishimura, M Duereh, Y Sugita, Y Yoshida, K Higuchi, M Tomi, ... Placenta 36 (6), 693-698, 2015 | 31 | 2015 |
| Design, synthesis, and blood–brain barrier transport study of pyrilamine derivatives as histone deacetylase inhibitors S Hiranaka, Y Tega, K Higuchi, T Kurosawa, Y Deguchi, M Arata, A Ito, ... ACS Medicinal Chemistry Letters 9 (9), 884-888, 2018 | 29 | 2018 |
| Cocktail-Dosing Microdialysis Study to Simultaneously Assess Delivery of Multiple Organic–Cationic Drugs to the Brain A Kitamura, T Okura, K Higuchi, Y Deguchi Journal of Pharmaceutical Sciences 105 (2), 935-940, 2016 | 29 | 2016 |
| System A amino acid transporter SNAT2 shows subtype-specific affinity for betaine and hyperosmotic inducibility in placental trophoblasts T Nishimura, R Yagi, M Usuda, K Oda, M Yamazaki, S Suda, Y Takahashi, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (5), 1306-1312, 2014 | 25 | 2014 |
| Proton-coupled organic cation antiporter-mediated uptake of apomorphine enantiomers in human brain capillary endothelial cell line hCMEC/D3 T Okura, K Higuchi, A Kitamura, Y Deguchi Biological and Pharmaceutical Bulletin 37 (2), 286-291, 2014 | 24 | 2014 |
| The hepatic plasma membrane citrate transporter NaCT (SLC13A5) as a molecular target for metformin J Kopel, K Higuchi, B Ristic, T Sato, S Ramachandran, V Ganapathy Scientific Reports 10 (1), 8536, 2020 | 23 | 2020 |
| Involvement of proton-coupled organic cation antiporter in varenicline transport at blood-brain barrier of rats and in human brain capillary endothelial cells T Kurosawa, K Higuchi, T Okura, K Kobayashi, H Kusuhara, Y Deguchi Journal of pharmaceutical sciences 106 (9), 2576-2582, 2017 | 22 | 2017 |
| Hypotaurine is a substrate of GABA transporter family members GAT2/Slc6a13 and TAUT/Slc6a6 T Nishimura, K Higuchi, Y Yoshida, Y Sugita-Fujisawa, K Kojima, ... Biological and Pharmaceutical Bulletin 41 (10), 1523-1529, 2018 | 20 | 2018 |
| Fetal growth retardation and lack of hypotaurine in ezrin knockout mice T Nishimura, K Higuchi, Y Sai, Y Sugita, Y Yoshida, M Tomi, M Wada, ... PloS one 9 (8), e105423, 2014 | 18 | 2014 |
| Mammalian monocarboxylate transporter 7 (MCT7/Slc16a6) is a novel facilitative taurine transporter K Higuchi, K Sugiyama, R Tomabechi, H Kishimoto, K Inoue Journal of Biological Chemistry 298 (4), 2022 | 17 | 2022 |
| Functional investigation of solute carrier family 35, member F2, in three cellular models of the primate blood-brain barrier T Mochizuki, T Mizuno, T Kurosawa, T Yamaguchi, K Higuchi, Y Tega, ... Drug Metabolism and Disposition 49 (1), 3-11, 2021 | 15 | 2021 |
| Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY) K Higuchi, JJ Kopel, S Sivaprakasam, V Jaramillo-Martinez, RB Sutton, ... Biochemical Journal 477 (21), 4149-4165, 2020 | 15 | 2020 |
| Estrogen receptor α induction by mitoxantrone increases Abcg2 expression in placental trophoblast cells K Oda, T Nishimura, K Higuchi, N Ishido, K Ochi, H Iizasa, Y Sai, M Tomi, ... Journal of Pharmaceutical Sciences 102 (9), 3364-3372, 2013 | 15 | 2013 |
| Differential expression of ezrin and CLP36 in the two layers of syncytiotrophoblast in rats K Higuchi, H Iizasa, Y Sai, S Horieya, KE Lee, M Wada, M Deguchi, ... Biological and Pharmaceutical Bulletin 33 (8), 1400-1406, 2010 | 12 | 2010 |
