Suivre
Loren W. Runnels
Loren W. Runnels
Associate Professor, Rutgers University
Adresse e-mail validée de rwjms.rutgers.edu
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The TRP ion channel family
DE Clapham, LW Runnels, C Strübing
Nature Reviews Neuroscience 2 (6), 387-396, 2001
15402001
TRP-PLIK, a bifunctional protein with kinase and ion channel activities
LW Runnels, L Yue, DE Clapham
Science 291 (5506), 1043-1047, 2001
8712001
The TRPM7 channel is inactivated by PIP2 hydrolysis
LW Runnels, L Yue, DE Clapham
Nature cell biology 4 (5), 329-336, 2002
6492002
TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain
LT Su, MA Agapito, M Li, WTN Simonson, A Huttenlocher, R Habas, L Yue, ...
Journal of Biological Chemistry 281 (16), 11260-11270, 2006
2872006
Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4, 5-bisphosphate in lateral domains
M Glaser, S Wanaski, CA Buser, V Boguslavsky, W Rashidzada, A Morris, ...
Journal of Biological Chemistry 271 (42), 26187-26193, 1996
2691996
Theory and application of fluorescence homotransfer to melittin oligomerization
LW Runnels, SF Scarlata
Biophysical journal 69 (4), 1569-1583, 1995
2681995
Molecular determinants of Mg2+ and Ca2+ permeability and pH sensitivity in TRPM6 and TRPM7
M Li, J Du, J Jiang, W Ratzan, LT Su, LW Runnels, L Yue
Journal of Biological Chemistry 282 (35), 25817-25830, 2007
2162007
Mechanism of activation of the Formin protein Daam1
W Liu, A Sato, D Khadka, R Bharti, H Diaz, LW Runnels, R Habas
Proceedings of the National Academy of Sciences 105 (1), 210-215, 2008
2122008
Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation
A Sato, DK Khadka, W Liu, R Bharti, LW Runnels, IB Dawid, R Habas
Oxford University Press for The Company of Biologists Limited 133 (21), 4219 …, 2006
1292006
Determination of the affinities between heterotrimeric G protein subunits and their phospholipase C-β effectors
LW Runnels, SF Scarlata
Biochemistry 38 (5), 1488-1496, 1999
1221999
Phosphatidylinositol 4,5-bisphosphate (PIP2) controls magnesium gatekeeper TRPM6 activity
J Xie, B Sun, J Du, W Yang, HC Chen, JD Overton, LW Runnels, L Yue
Scientific reports 1 (1), 146, 2011
1012011
TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions
L W Runnels
Current pharmaceutical biotechnology 12 (1), 42-53, 2011
992011
TRPM7 regulates polarized cell movements
LT Su, W Liu, HC Chen, O González-Pagán, R Habas, LW Runnels
Biochemical Journal 434 (3), 513-521, 2011
922011
Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs
E Tall, G Dormán, P Garcia, L Runnels, S Shah, J Chen, A Profit, QM Gu, ...
Biochemistry 36 (23), 7239-7248, 1997
911997
TRPM7 activates m-calpain by stress-dependent stimulation of p38 MAPK and c-Jun N-terminal kinase
LT Su, HC Chen, O González-Pagán, JD Overton, J Xie, L Yue, ...
Journal of molecular biology 396 (4), 858-869, 2010
882010
TRPM7 regulates gastrulation during vertebrate embryogenesis
W Liu, LT Su, DK Khadka, C Mezzacappa, Y Komiya, A Sato, R Habas, ...
Developmental biology 350 (2), 348-357, 2011
872011
Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase
HC Chen, J Xie, Z Zhang, LT Su, L Yue, LW Runnels
PLoS One 5 (6), e11161, 2010
872010
Membrane Binding of Phospholipases C-β1 and C-β2 Is Independent of Phosphatidylinositol 4,5-Bisphosphate and the α and βγ Subunits of G Proteins
LW Runnels, J Jenco, A Morris, S Scarlata
Biochemistry 35 (51), 16824-16832, 1996
851996
Identification of a novel binding partner of phospholipase Cβ1: translin-associated factor X
OR Aisiku, LW Runnels, S Scarlata
PloS one 5 (11), e15001, 2010
562010
TRPM channels and magnesium in early embryonic development
Y Komiya, LW Runnels
The International journal of developmental biology 59, 281, 2015
552015
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