| How pyridoxal 5′‐phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state G Giardina, P Brunotti, A Fiascarelli, A Cicalini, MGS Costa, AM Buckle, ... The FEBS journal 282 (7), 1225-1241, 2015 | 92 | 2015 |
| Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor: Gq complex M Damian, S Mary, M Maingot, C M'Kadmi, D Gagne, JP Leyris, ... Proceedings of the National Academy of Sciences 112 (5), 1601-1606, 2015 | 89 | 2015 |
| Exploring free energy landscapes of large conformational changes: molecular dynamics with excited normal modes MGS Costa, PR Batista, PM Bisch, D Perahia Journal of chemical theory and computation 11 (6), 2755-2767, 2015 | 59 | 2015 |
| High temperatures enhance cooperative motions between CBM and catalytic domains of a thermostable cellulase: mechanism insights from essential dynamics PR Batista, MG de Souza Costa, PG Pascutti, PM Bisch, W de Souza Physical Chemistry Chemical Physics 13 (30), 13709-13720, 2011 | 44 | 2011 |
| Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis I Kass, DE Hoke, MGS Costa, CF Reboul, BT Porebski, NP Cowieson, ... Proceedings of the National Academy of Sciences 111 (25), E2524-E2529, 2014 | 43 | 2014 |
| MicroRNA biophysically modulates cardiac action potential by direct binding to ion channel D Yang, X Wan, AT Dennis, E Bektik, Z Wang, MGS Costa, C Fagnen, ... Circulation 143 (16), 1597-1613, 2021 | 37 | 2021 |
| Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics BT Riley, O Ilyichova, MGS Costa, BT Porebski, SJ De Veer, JE Swedberg, ... Scientific reports 6 (1), 35385, 2016 | 35 | 2016 |
| Reactive centre loop dynamics and serpin specificity EM Marijanovic, J Fodor, BT Riley, BT Porebski, MGS Costa, I Kass, ... Scientific reports 9 (1), 3870, 2019 | 34 | 2019 |
| How does heparin prevent the pH inactivation of cathepsin B? Allosteric mechanism elucidated by docking and molecular dynamics MGS Costa, PR Batista, CS Shida, CH Robert, PM Bisch, PG Pascutti BMC genomics 11, 1-15, 2010 | 34 | 2010 |
| Understanding the HIV-1 protease nelfinavir resistance mutation D30N in subtypes B and C through molecular dynamics simulations RO Soares, PR Batista, MGS Costa, LE Dardenne, PG Pascutti, ... Journal of Molecular Graphics and Modelling 29 (2), 137-147, 2010 | 31 | 2010 |
| Conformational equilibrium of cdk/cyclin complexes by molecular dynamics with excited normal modes N Floquet, MGS Costa, PR Batista, P Renault, PM Bisch, F Raussin, ... Biophysical journal 109 (6), 1179-1189, 2015 | 29 | 2015 |
| Unraveling RNA dynamical behavior of TPP riboswitches: a comparison between Escherichia coli and Arabidopsis thaliana D Antunes, NAN Jorge, M Garcia de Souza Costa, F Passetti, ... Scientific reports 9 (1), 4197, 2019 | 21 | 2019 |
| Unraveling the molecular mechanisms of nitrogenase conformational protection against oxygen in diazotrophic bacteria LMS Lery, M Bitar, MGS Costa, SCS Rössle, PM Bisch BMC genomics 11, 1-11, 2010 | 20 | 2010 |
| A new strategy for atomic flexible fitting in cryo-EM maps by molecular dynamics with excited normal modes (MDeNM-EMfit) MGS Costa, C Fagnen, C Vénien-Bryan, D Perahia Journal of chemical information and modeling 60 (5), 2419-2423, 2020 | 19 | 2020 |
| Sampling of protein conformational space using hybrid simulations: A critical assessment of recent methods BT Kaynak, JM Krieger, B Dudas, ZL Dahmani, MGS Costa, E Balog, ... Frontiers in molecular biosciences 9, 832847, 2022 | 18 | 2022 |
| Smoothing a rugged protein folding landscape by sequence-based redesign BT Porebski, S Keleher, JJ Hollins, AA Nickson, EM Marijanovic, NA Borg, ... Scientific Reports 6 (1), 33958, 2016 | 18 | 2016 |
| Impact of M36I polymorphism on the interaction of HIV-1 protease with its substrates: insights from molecular dynamics MGS Costa, TG Benetti-Barbosa, N Desdouits, A Blondel, PM Bisch, ... BMC genomics 15, 1-15, 2014 | 14 | 2014 |
| Effects of pH and aggregation in the human prion conversion into scrapie form: a study using molecular dynamics with excited normal modes AN Lima, RJ de Oliveira, ASK Braz, MG de Souza Costa, D Perahia, ... European Biophysics Journal 47, 583-590, 2018 | 13 | 2018 |
| Dynamics on human T oll‐like receptor 4 complexation to MD‐2: The coreceptor stabilizing function C de Aguiar, MGS Costa, H Verli Proteins: Structure, Function, and Bioinformatics 83 (2), 373-382, 2015 | 13 | 2015 |
| Computational engineering of cellulase Cel9A-68 functional motions through mutations in its linker region MGS Costa, YF Silva, PR Batista Physical Chemistry Chemical Physics 20 (11), 7643-7652, 2018 | 12 | 2018 |
David PerahiaResearch Director Emeritus, Ecole Normale Supérieure de Cachan, FranceVerified email at ens-cachan.fr
