Perturbation-response genes reveal signaling footprints in cancer gene expression M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ... Nature communications 9 (1), 20, 2018 | 702 | 2018 |
A compendium of ERK targets EB Ünal, F Uhlitz, N Blüthgen FEBS letters 591 (17), 2607-2615, 2017 | 204 | 2017 |
Ovarian cancer mutational processes drive site-specific immune evasion I Vázquez-García, F Uhlitz, N Ceglia, JLP Lim, M Wu, N Mohibullah, ... Nature, 1-9, 2022 | 168 | 2022 |
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma P Bischoff, A Trinks, B Obermayer, JP Pett, J Wiederspahn, F Uhlitz, ... Oncogene 40 (50), 6748-6758, 2021 | 136 | 2021 |
Single-cell genomic variation induced by mutational processes in cancer T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ... Nature, 1-10, 2022 | 101* | 2022 |
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium R Brandt, T Sell, M Lüthen, F Uhlitz, B Klinger, P Riemer, ... Nature Communications 10 (1), 2919, 2019 | 88 | 2019 |
Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer F Uhlitz, P Bischoff, S Peidli, A Sieber, A Trinks, M Lüthen, B Obermayer, ... EMBO molecular medicine 13 (10), e14123, 2021 | 82 | 2021 |
An immediate–late gene expression module decodes ERK signal duration F Uhlitz, A Sieber, E Wyler, R Fritsche‐Guenther, J Meisig, M Landthaler, ... Molecular systems biology 13 (5), 928, 2017 | 70 | 2017 |
SFPQ depletion is synthetically lethal with BRAFV600E in colorectal cancer cells K Klotz-Noack, B Klinger, M Rivera, N Bublitz, F Uhlitz, P Riemer, ... Cell reports 32 (12), 2020 | 38 | 2020 |
Mutation-specific effects of NRAS oncogenes in colorectal cancer cells N Kuhn, B Klinger, F Uhlitz, A Sieber, M Rivera, K Klotz-Noack, I Fichtner, ... Advances in Biological Regulation 79, 100778, 2021 | 13 | 2021 |
Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector N Ceglia, Z Sethna, SS Freeman, F Uhlitz, V Bojilova, N Rusk, B Burman, ... Nature Communications 14 (1), 4400, 2023 | 7* | 2023 |
Rejuvenating dysfunctional T cells in ovarian cancer: CD28 is the license to kill F Uhlitz, D Zamarin Cancer Cell 39 (12), 1567-1569, 2021 | 4 | 2021 |
Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer A McPherson, I Vázquez-García, MA Myers, M Zatzman, D Al-Rawi, ... bioRxiv, 2024.07. 11.602772, 2024 | 2 | 2024 |
Abstract PR012: Evolutionary dynamics of whole-genome doubling in ovarian cancer I Vázquez-García, M Myers, MJ Williams, SS Freeman, J Li, H Shi, ... Cancer Research 84 (3_Supplement_2), PR012-PR012, 2024 | | 2024 |
Targeted Perturb-seq Reveals EGR1 and FOS as Key Regulators of the Transcriptional RAF-MAPK Response GE Kassem, A Sieber, B Klinger, F Uhlitz, D Steinbrecht, M van Bentum, ... bioRxiv, 2024.01. 13.575500, 2024 | | 2024 |
Transient chromosomal instability as a driver of ovarian cancer genome evolution I Vazquez-Garcia, F Uhlitz, MJ Williams, J Li, H Shi, S Freeman, M Myers, ... Cancer Research 83 (7_Supplement), 102-102, 2023 | | 2023 |
EP299/# 232 Genomic instability as a determinant of immune escape in ovarian cancer I Vazquez-Garcia, F Uhlitz, N Ceglia, J Lim, M Wu, N Mohibullah, ... International Journal of Gynecological Cancer 32 (Suppl 3), A174-A174, 2022 | | 2022 |
Abstract LB049: Spatial immune determinants of ICB response in STK11-mutated non-small cell lung cancer F Uhlitz, D Linn, EB Krall, J Egger, H Rizvi, J Chang, B Nicholson, ... Cancer Research 82 (12_Supplement), LB049-LB049, 2022 | | 2022 |
Vector Representation of Gene Co-expression in Single Cell RNA-Seq N Ceglia, F Uhlitz, A McPherson EasyChair, 2020 | | 2020 |
Single cell analysis of colorectal cancer identifies mitogen-activated protein kinase as a key driver of tumor cell plasticity F Uhlitz, P Bischoff, S Peidli, A Sieber, B Obermayer, E Blanc, A Trinks, ... bioRxiv, 2020.01. 10.901579, 2020 | | 2020 |