| A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. DE Brash, JA Rudolph, JA Simon, A Lin, GJ McKenna, HP Baden, ... Proceedings of the National Academy of Sciences 88 (22), 10124-10128, 1991 | 2450 | 1991 |
| Sunburn and p53 in the onset of skin cancer A Ziegler, AS Jonason, DJ Leffellt, JA Simon, HW Sharma, J Kimmelman, ... Nature 372 (6508), 773-776, 1994 | 1863 | 1994 |
| Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma M Krauthammer, Y Kong, BH Ha, P Evans, A Bacchiocchi, JP McCusker, ... Nature genetics 44 (9), 1006-1014, 2012 | 1358 | 2012 |
| The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas MR Gailani, M Ståhle-Bäckdahl, DJ Leffell, M Glyn, PG Zaphiropoulos, ... Nature genetics 14 (1), 78-81, 1996 | 969 | 1996 |
| Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a … RR Reddel, Y Ke, BI Gerwin, MG McMenamin, JF Lechner, RT Su, ... Cancer research 48 (7), 1904-1909, 1988 | 954 | 1988 |
| Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers A Ziegler, DJ Leffell, S Kunala, HW Sharma, M Gailani, JA Simon, ... Proceedings of the National Academy of Sciences 90 (9), 4216, 1993 | 923 | 1993 |
| Frequent clones of p53-mutated keratinocytes in normal human skin AS Jonason, S Kunala, GJ Price, RJ Restifo, HM Spinelli, JA Persing, ... Proceedings of the National Academy of Sciences 93 (24), 14025-14029, 1996 | 778 | 1996 |
| Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion. DE Brash, A Ziegler, AS Jonason, JA Simon, S Kunala, DJ Leffell The journal of investigative dermatology. Symposium proceedings 1 (2), 136-142, 1996 | 649 | 1996 |
| Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure S Premi, S Wallisch, CM Mano, AB Weiner, A Bacchiocchi, K Wakamatsu, ... Science 347 (6224), 842-847, 2015 | 563 | 2015 |
| UV-induced mutation hotspots occur at DNA damage hotspots DE Brash, WA Haseltine Nature 298 (5870), 189-192, 1982 | 495 | 1982 |
| UV signature mutations DE Brash Photochemistry and photobiology 91 (1), 15-26, 2015 | 473 | 2015 |
| Sunlight and the onset of skin cancer DE Brash Trends in genetics 13 (10), 410-414, 1997 | 387 | 1997 |
| Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences. JA Lippke, LK Gordon, DE Brash, WA Haseltine Proceedings of the National Academy of Sciences 78 (6), 3388-3392, 1981 | 344 | 1981 |
| Common contaminants in next-generation sequencing that hinder discovery of low-abundance microbes M Laurence, C Hatzis, DE Brash PloS one 9 (5), e97876, 2014 | 332 | 2014 |
| Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53 D Grossman, PJ Kim, OP Blanc-Brude, DE Brash, S Tognin, PC Marchisio, ... The Journal of clinical investigation 108 (7), 991-999, 2001 | 328 | 2001 |
| Keratinocyte apoptosis in epidermal development and disease D Raj, DE Brash, D Grossman Journal of Investigative Dermatology 126 (2), 243-257, 2006 | 320 | 2006 |
| UV mutagenic photoproducts in Escherichia coli and human cells: a molecular genetics perspective on human skin cancer DE Brash Photochemistry and photobiology 48 (1), 59-66, 1988 | 320 | 1988 |
| Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells. DE Brash, S Seetharam, KH Kraemer, MM Seidman, A Bredberg Proceedings of the National Academy of Sciences 84 (11), 3782-3786, 1987 | 292 | 1987 |
| Ultraviolet radiation induced signature mutations in photocarcinogenesis NM Wikonkal, DE Brash Journal of Investigative Dermatology Symposium Proceedings 4 (1), 6-10, 1999 | 270 | 1999 |
| Relationship between sunlight exposure and a key genetic alteration in basal cell carcinoma MR Gailani, DJ Leffell, AM Ziegler, EG Gross, DE Brash, AE Bale JNCI: Journal of the National Cancer Institute 88 (6), 349-354, 1996 | 256 | 1996 |
