Lydia Teboul
Lydia Teboul
Mary Lyon Centre - MRC Harwell Institute
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Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
M Haeussler, K Schönig, H Eckert, A Eschstruth, J Mianné, JB Renaud, ...
Genome biology 17 (1), 148, 2016
NAADP mobilizes calcium from acidic organelles through two-pore channels
PJ Calcraft, M Ruas, Z Pan, X Cheng, A Arredouani, X Hao, J Tang, ...
Nature 459 (7246), 596-600, 2009
Overexpression of Fto leads to increased food intake and results in obesity
C Church, L Moir, F McMurray, C Girard, GT Banks, L Teboul, S Wells, ...
Nature genetics 42 (12), 1086, 2010
High-throughput discovery of novel developmental phenotypes
ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ...
Nature 537 (7621), 508-514, 2016
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex
L Nguyen, A Besson, JIT Heng, C Schuurmans, L Teboul, C Parras, ...
Genes & development 20 (11), 1511-1524, 2006
Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells
L Teboul, D Gaillard, L Staccini, H Inadera, EZ Amri, PA Grimaldi
Journal of Biological Chemistry 270 (47), 28183-28187, 1995
The mammalian gene function resource: the International Knockout Mouse Consortium
A Bradley, K Anastassiadis, A Ayadi, JF Battey, C Bell, MC Birling, ...
Mammalian genome 23 (9-10), 580-586, 2012
Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells.
A Ibrahimi, L Teboul, D Gaillard, EZ Amri, G Ailhaud, P Young, ...
Molecular pharmacology 46 (6), 1070-1076, 1994
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse
F McMurray, CD Church, R Larder, G Nicholson, S Wells, L Teboul, ...
PLoS Genet 9 (1), e1003166, 2013
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
Mouse large-scale phenotyping initiatives: Overview of the European mouse disease clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project
A Ayadi, MC Birling, J Bottomley, J Bussell, H Fuchs, M Fray, ...
Mammalian genome 23 (9-10), 600-610, 2012
Prevalence of sexual dimorphism in mammalian phenotypic traits
NA Karp, J Mason, AL Beaudet, Y Benjamini, L Bower, RE Braun, ...
Nature communications 8 (1), 1-12, 2017
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
MH de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ...
Nature genetics 47 (9), 969-978, 2015
Fatty acids regulate the expression of lipoprotein lipase gene and activity in preadipose and adipose cells
Biochemical Journal 314 (2), 541-546, 1996
Trans-differentiation of myoblasts to adipoblasts: triggering effects of fatty acids and thiazolidinediones
PA Grimaldi, L Teboul, H Inadera, D Gaillard, EZ Amri
Prostaglandins, leukotrienes and essential fatty acids 57 (1), 71-75, 1997
Structural and functional characterization of the mouse fatty acid translocase promoter: activation during adipose differentiation
L Teboul, M Febbraio, D Gaillard, EZ AMRI, R Silverstein, PA Grimaldi
Biochemical Journal 360 (2), 305-312, 2001
Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster
CM Williamson, ST Ball, C Dawson, S Mehta, CV Beechey, M Fray, ...
PLoS Genet 7 (3), e1001347, 2011
Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair
J Mianné, L Chessum, S Kumar, C Aguilar, G Codner, M Hutchison, ...
Genome medicine 8 (1), 16, 2016
The early epaxial enhancer is essential for the initial expression of the skeletal muscle determination gene Myf5 but not for subsequent, multiple phases of somitic myogenesis
L Teboul, J Hadchouel, P Daubas, D Summerbell, M Buckingham, ...
Development 129 (19), 4571-4580, 2002
TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2
M Ruas, KT Chuang, LC Davis, A Al-Douri, PW Tynan, R Tunn, L Teboul, ...
Molecular and cellular biology 34 (21), 3981-3992, 2014
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