Muhammad Hamid Zaman
Muhammad Hamid Zaman
HHMI Professor of Biomedical Engineering
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Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis
MH Zaman, LM Trapani, AL Sieminski, D MacKellar, H Gong, RD Kamm, ...
Proceedings of the National Academy of Sciences 103 (29), 10889-10894, 2006
Collective cell guidance by cooperative intercellular forces
DT Tambe, CC Hardin, TE Angelini, K Rajendran, CY Park, ...
Nature materials 10 (6), 469-475, 2011
Microarchitecture of three-dimensional scaffolds influences cell migration behavior via junction interactions
BAC Harley, HD Kim, MH Zaman, IV Yannas, DA Lauffenburger, ...
Biophysical journal 95 (8), 4013-4024, 2008
Impact of the physical microenvironment on tumor progression and metastasis
F Spill, DS Reynolds, RD Kamm, MH Zaman
Current opinion in biotechnology 40, 41-48, 2016
Computational model for cell migration in three-dimensional matrices
MH Zaman, RD Kamm, P Matsudaira, DA Lauffenburger
Biophysical journal 89 (2), 1389-1397, 2005
Effects of HER2 overexpression on cell signaling networks governing proliferation and migration
A Wolf‐Yadlin, N Kumar, Y Zhang, S Hautaniemi, M Zaman, HD Kim, ...
Molecular systems biology 2 (1), 54, 2006
Extracellular matrix stiffness and architecture govern intracellular rheology in cancer
EL Baker, RT Bonnecaze, MH Zaman
Biophysical journal 97 (4), 1013-1021, 2009
Helix, sheet, and polyproline II frequencies and strong nearest neighbor effects in a restricted coil library
AK Jha, A Colubri, MH Zaman, S Koide, TR Sosnick, KF Freed
Biochemistry 44 (28), 9691-9702, 2005
Low-cost tools for diagnosing and monitoring HIV infection in low-resource settings
G Wu, MH Zaman
Bulletin of the World Health Organization 90, 914-920, 2012
Cancer cell stiffness: integrated roles of three-dimensional matrix stiffness and transforming potential
EL Baker, J Lu, D Yu, RT Bonnecaze, MH Zaman
Biophysical journal 99 (7), 2048-2057, 2010
Investigations into sequence and conformational dependence of backbone entropy, inter-basin dynamics and the Flory isolated-pair hypothesis for peptides
MH Zaman, MY Shen, RS Berry, KF Freed, TR Sosnick
Journal of molecular biology 331 (3), 693-711, 2003
Embedded multicellular spheroids as a biomimetic 3D cancer model for evaluating drug and drug-device combinations
KM Charoen, B Fallica, YL Colson, MH Zaman, MW Grinstaff
Biomaterials 35 (7), 2264-2271, 2014
The biomechanical integrin
EL Baker, MH Zaman
Journal of biomechanics 43 (1), 38-44, 2010
A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration
MP Schwartz, BD Fairbanks, RE Rogers, R Rangarajan, MH Zaman, ...
Integrative Biology 2 (1), 32-40, 2010
Understanding effects of matrix protease and matrix organization on directional persistence and translational speed in three-dimensional cell migration
MH Zaman, P Matsudaira, DA Lauffenburger
Annals of biomedical engineering 35 (1), 91-100, 2007
Modeling the mechanics of cancer: effect of changes in cellular and extra-cellular mechanical properties
P Katira, RT Bonnecaze, MH Zaman
Frontiers in oncology 3, 145, 2013
Alteration of cellular behavior and response to PI3K pathway inhibition by culture in 3D collagen gels
B Fallica, JS Maffei, S Villa, G Makin, M Zaman
Public Library of Science 7 (10), e48024, 2012
Dependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidence
H Enderling, NR Alexander, ES Clark, KM Branch, L Estrada, C Crooke, ...
Biophysical journal 95 (5), 2203-2218, 2008
COVID-19 and risks to the supply and quality of tests, drugs, and vaccines
PN Newton, KC Bond, M Adeyeye, M Antignac, A Ashenef, GR Awab, ...
The Lancet Global Health 8 (6), e754-e755, 2020
Breast cancer spheroids reveal a differential cancer stem cell response to chemotherapeutic treatment
DS Reynolds, KM Tevis, WA Blessing, YL Colson, MH Zaman, ...
Scientific reports 7 (1), 1-12, 2017
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