| Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrindine (MPTP) and oxidative stress RH Kim, PD Smith, H Aleyasin, S Hayley, MP Mount, S Pownall, ... Proceedings of the National Academy of Sciences 102 (14), 5215-5220, 2005 | 834 | 2005 |
| DJ-1, a novel regulator of the tumor suppressor PTEN RH Kim, M Peters, YJ Jang, W Shi, M Pintilie, GC Fletcher, C DeLuca, ... Cancer cell 7 (3), 263-273, 2005 | 670 | 2005 |
| Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study A Villani, A Shore, JD Wasserman, D Stephens, RH Kim, H Druker, ... The Lancet Oncology 17 (9), 1295-1305, 2016 | 473 | 2016 |
| Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ... Human molecular genetics 19 (19), 3734-3746, 2010 | 451 | 2010 |
| Utility of whole‐exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care SL Sawyer, T Hartley, DA Dyment, CL Beaulieu, J Schwartzentruber, ... Clinical genetics 89 (3), 275-284, 2016 | 418 | 2016 |
| Whole-genome sequencing expands diagnostic utility and improves clinical management in paediatric medicine DJ Stavropoulos, D Merico, R Jobling, S Bowdin, N Monfared, ... NPJ genomic medicine 1 (1), 1-9, 2016 | 368 | 2016 |
| Reappraisal of reported genes for sudden arrhythmic death: evidence-based evaluation of gene validity for Brugada syndrome SM Hosseini, R Kim, S Udupa, G Costain, R Jobling, E Liston, SM Jamal, ... Circulation 138 (12), 1195-1205, 2018 | 294 | 2018 |
| Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial TL Stockley, AM Oza, HK Berman, NB Leighl, JJ Knox, FA Shepherd, ... Genome medicine 8, 1-12, 2016 | 243 | 2016 |
| ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons AP Joselin, SJ Hewitt, SM Callaghan, RH Kim, YH Chung, TW Mak, ... Human molecular genetics 21 (22), 4888-4903, 2012 | 238 | 2012 |
| DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway H Aleyasin, MWC Rousseaux, PC Marcogliese, SJ Hewitt, I Irrcher, ... Proceedings of the National Academy of Sciences 107 (7), 3186-3191, 2010 | 195 | 2010 |
| The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage H Aleyasin, MWC Rousseaux, M Phillips, RH Kim, RJ Bland, S Callaghan, ... Proceedings of the National Academy of Sciences 104 (47), 18748-18753, 2007 | 186 | 2007 |
| Primary ciliary dyskinesia and neonatal respiratory distress T Mullowney, D Manson, R Kim, D Stephens, V Shah, S Dell Pediatrics 134 (6), 1160-1166, 2014 | 183 | 2014 |
| No. 348-Joint SOGC-CCMG guideline: update on prenatal screening for fetal aneuploidy, fetal anomalies, and adverse pregnancy outcomes F Audibert, I De Bie, JA Johnson, N Okun, RD Wilson, C Armour, ... J Obstet Gynaecol Can 39 (9), 805-17, 2017 | 148 | 2017 |
| Recommendations for the integration of genomics into clinical practice S Bowdin, A Gilbert, E Bedoukian, C Carew, MP Adam, J Belmont, ... Genetics in Medicine 18 (11), 1075-1084, 2016 | 148 | 2016 |
| Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo F Billia, L Hauck, D Grothe, F Konecny, V Rao, RH Kim, TW Mak Proceedings of the National Academy of Sciences 110 (15), 6085-6090, 2013 | 116 | 2013 |
| Tumours and tremors: how PTEN regulation underlies both RH Kim, TW Mak British journal of cancer 94 (5), 620-624, 2006 | 105 | 2006 |
| Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease MWC Rousseaux, PC Marcogliese, D Qu, SJ Hewitt, S Seang, RH Kim, ... Proceedings of the National Academy of Sciences 109 (39), 15918-15923, 2012 | 98 | 2012 |
| Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease MWC Rousseaux, PC Marcogliese, D Qu, SJ Hewitt, S Seang, RH Kim, ... Proceedings of the National Academy of Sciences 109 (39), 15918-15923, 2012 | 98 | 2012 |
| DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice SY Shi, SY Lu, T Sivasubramaniyam, XS Revelo, EP Cai, CT Luk, ... Nature communications 6 (1), 7415, 2015 | 90 | 2015 |
| Next-Generation Service Delivery: A Scoping Review of Patient Outcomes Associated with Alternative Models of Genetic Counseling and Genetic Testing for Hereditary Cancer J McCuaig, S Armel, M Care, A Volenik, R Kim, K Metcalfe Cancers 10 (11), 435, 2018 | 85 | 2018 |
