David C. Samuels
David C. Samuels
Associate Professor, Molecular Physiology and Biophysics, Vanderbilt University Medical Center
Adresse e-mail validée de vanderbilt.edu - Page d'accueil
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Pathogenic mitochondrial DNA mutations are common in the general population
HR Elliott, DC Samuels, JA Eden, CL Relton, PF Chinnery
The American journal of human genetics 83 (2), 254-260, 2008
5532008
Mitochondrial DNA mutations in human colonic crypt stem cells
RW Taylor, MJ Barron, GM Borthwick, A Gospel, PF Chinnery, ...
The Journal of clinical investigation 112 (9), 1351-1360, 2003
5462003
A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes
LM Cree, DC Samuels, SC de Sousa Lopes, HK Rajasimha, ...
Nature genetics 40 (2), 249-254, 2008
4352008
What causes mitochondrial DNA deletions in human cells?
KJ Krishnan, AK Reeve, DC Samuels, PF Chinnery, JK Blackwood, ...
Nature genetics 40 (3), 275, 2008
4022008
Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age
JL Elson, DC Samuels, DM Turnbull, PF Chinnery
The American Journal of Human Genetics 68 (3), 802-806, 2001
3162001
Universal heteroplasmy of human mitochondrial DNA
BAI Payne, IJ Wilson, P Yu-Wai-Man, J Coxhead, D Deehan, R Horvath, ...
Human molecular genetics 22 (2), 384-390, 2013
3012013
The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both?
PF Chinnery, DR Thorburn, DC Samuels, SL White, HHM Dahl, ...
Trends in Genetics 16 (11), 500-505, 2000
2842000
Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?
PF Chinnery, DC Samuels, J Elson, DM Turnbull
The Lancet 360 (9342), 1323-1325, 2002
2602002
Sound emission due to superfluid vortex reconnections
M Leadbeater, T Winiecki, DC Samuels, CF Barenghi, CS Adams
Physical Review Letters 86 (8), 1410, 2001
2082001
Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations
BAI Payne, IJ Wilson, CA Hateley, R Horvath, M Santibanez-Koref, ...
Nature genetics 43 (8), 806-810, 2011
2042011
Relaxed replication of mtDNA: a model with implications for the expression of disease
PF Chinnery, DC Samuels
The American Journal of Human Genetics 64 (4), 1158-1165, 1999
1971999
Large scale comparison of gene expression levels by microarrays and RNAseq using TCGA data
Y Guo, Q Sheng, J Li, F Ye, DC Samuels, Y Shyr
PloS one 8 (8), e71462, 2013
1822013
Two direct repeats cause most human mtDNA deletions
DC Samuels, EA Schon, PF Chinnery
TRENDS in Genetics 20 (9), 393-398, 2004
1772004
Kelvin waves cascade in superfluid turbulence
D Kivotides, JC Vassilicos, DC Samuels, CF Barenghi
Physical review letters 86 (14), 3080, 2001
1732001
Random genetic drift determines the level of mutant mtDNA in human primary oocytes
DT Brown, DC Samuels, EM Michael, DM Turnbull, PF Chinnery
The American Journal of Human Genetics 68 (2), 533-536, 2001
1682001
Epigenetics, epidemiology and mitochondrial DNA diseases
PF Chinnery, HR Elliott, G Hudson, DC Samuels, CL Relton
International journal of epidemiology 41 (1), 177-187, 2012
1662012
The diversity present in 5140 human mitochondrial genomes
L Pereira, F Freitas, V Fernandes, JB Pereira, MD Costa, S Costa, ...
The American Journal of Human Genetics 84 (5), 628-640, 2009
1342009
Superfluid vortex lines in a model of turbulent flow
CF Barenghi, DC Samuels, GH Bauer, RJ Donnelly
Physics of fluids 9 (9), 2631-2643, 1997
1291997
Finding the lost treasures in exome sequencing data
DC Samuels, L Han, J Li, S Quanghu, TA Clark, Y Shyr, Y Guo
Trends in Genetics 29 (10), 593-599, 2013
1222013
Three-stage quality control strategies for DNA re-sequencing data
Y Guo, F Ye, Q Sheng, T Clark, DC Samuels
Briefings in bioinformatics 15 (6), 879-889, 2014
1172014
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