| Phenotype molding of stromal cells in the lung tumor microenvironment D Lambrechts, E Wauters, B Boeckx, S Aibar, D Nittner, O Burton, ... Nature medicine 24 (8), 1277-1289, 2018 | 928 | 2018 |
| The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells S Seisenberger, S Andrews, F Krueger, J Arand, J Walter, F Santos, ... Molecular cell 48 (6), 849-862, 2012 | 915 | 2012 |
| Single-Cell Transcriptome Atlas of Murine Endothelial Cells J Kalucka, LPMH de Rooij, J Goveia, K Rohlenova, SJ Dumas, E Meta, ... Cell 180 (4), 764-779. e20, 2020 | 501 | 2020 |
| Tumour hypoxia causes DNA hypermethylation by reducing TET activity B Thienpont, J Steinbacher, H Zhao, F D’Anna, A Kuchnio, A Ploumakis, ... Nature 537 (7618), 63-68, 2016 | 491 | 2016 |
| A single-cell transcriptome atlas of the aging Drosophila brain K Davie, J Janssens, D Koldere, M De Waegeneer, U Pech, Ł Kreft, ... Cell 174 (4), 982-998. e20, 2018 | 460 | 2018 |
| Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of … B Menten, N Maas, B Thienpont, K Buysse, J Vandesompele, C Melotte, ... Journal of medical genetics 43 (8), 625-633, 2006 | 454 | 2006 |
| Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ... Cancer cell 30 (6), 968-985, 2016 | 433 | 2016 |
| Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing A Sifrim, MP Hitz, A Wilsdon, J Breckpot, SH Al Turki, B Thienpont, ... Nature genetics 48 (9), 1060-1065, 2016 | 319 | 2016 |
| Single-cell chromosomal imbalances detection by array CGH C Le Caignec, C Spits, K Sermon, M De Rycke, B Thienpont, S Debrock, ... Nucleic acids research 34 (9), e68-e68, 2006 | 257 | 2006 |
| A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling J Qian, S Olbrecht, B Boeckx, H Vos, D Laoui, E Etlioglu, E Wauters, ... Cell research 30 (9), 745-762, 2020 | 229 | 2020 |
| Submicroscopic chromosomal imbalances detected by array-CGH are a frequent cause of congenital heart defects in selected patients B Thienpont, L Mertens, T de Ravel, B Eyskens, D Boshoff, N Maas, ... European heart journal 28 (22), 2778-2784, 2007 | 229 | 2007 |
| The role of fatty acid β-oxidation in lymphangiogenesis BW Wong, X Wang, A Zecchin, B Thienpont, I Cornelissen, J Kalucka, ... Nature 542 (7639), 49-54, 2017 | 226 | 2017 |
| An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ... Cancer Cell 37 (1), 21-36. e13, 2020 | 207 | 2020 |
| Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotection via redox homeostasis J Kalucka, L Bierhansl, NV Conchinha, R Missiaen, I Elia, U Brüning, ... Cell metabolism 28 (6), 881-894. e13, 2018 | 158 | 2018 |
| Rare variants in NR2F2 cause congenital heart defects in humans S Al Turki, AK Manickaraj, CL Mercer, SS Gerety, MP Hitz, S Lindsay, ... The American Journal of Human Genetics 94 (4), 574-585, 2014 | 154 | 2014 |
| Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1 KB Meyer, M O’Reilly, K Michailidou, S Carlebur, SL Edwards, JD French, ... The American Journal of Human Genetics 93 (6), 1046-1060, 2013 | 140 | 2013 |
| Genotype–phenotype correlation in 21 patients with Wolf–Hirschhorn syndrome using high resolution array comparative genome hybridisation (CGH) NMC Maas, G Van Buggenhout, F Hannes, B Thienpont, D Sanlaville, ... Journal of medical genetics 45 (2), 71-80, 2008 | 140 | 2008 |
| Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation M Ghoussaini, SL Edwards, K Michailidou, S Nord, R Cowper-Sal, ... Nature communications 5 (1), 1-12, 2014 | 128 | 2014 |
| Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis K Rohlenova, J Goveia, M García-Caballero, A Subramanian, J Kalucka, ... Cell Metabolism 31 (4), 862-877. e14, 2020 | 124 | 2020 |
| HIF-1α promotes glutamine-mediated redox homeostasis and glycogen-dependent bioenergetics to support postimplantation bone cell survival S Stegen, N van Gastel, G Eelen, B Ghesquière, F D’Anna, B Thienpont, ... Cell metabolism 23 (2), 265-279, 2016 | 124 | 2016 |
Diether LambrechtsLaboratory for Translational Genetics, Department of Oncology, VIB and KULeuven, Leuven, BelgiumAdresse e-mail validée de vib-kuleuven.be
