Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? MD Carcao, P Chelle, E Clarke, L Kim, L Tiseo, M Morfini, T Hossain, ... Journal of Thrombosis and Haemostasis 17 (7), 1085-1096, 2019 | 40 | 2019 |
Development and evaluation of the population pharmacokinetic models for FVIII and FIX concentrates of the WAPPS‐Hemo project DM Hajducek, P Chelle, C Hermans, A Iorio, A McEneny‐King, J Yu, ... Haemophilia 26 (3), 384-400, 2020 | 37 | 2020 |
Biodistribution and physiologically-based pharmacokinetic modeling of gold nanoparticles in mice with interspecies extrapolation M Aborig, PRV Malik, S Nambiar, P Chelle, J Darko, A Mutsaers, ... Pharmaceutics 11 (4), 179, 2019 | 37 | 2019 |
Development and evaluation of a generic population pharmacokinetic model for standard half-life factor VIII for use in dose individualization A McEneny-King, P Chelle, G Foster, A Keepanasseril, A Iorio, ... Journal of Pharmacokinetics and Pharmacodynamics 46, 411-426, 2019 | 36 | 2019 |
Modeling of body weight metrics for effective and cost-efficient conventional factor VIII dosing in hemophilia A prophylaxis A McEneny-King, P Chelle, S Henrard, C Hermans, A Iorio, AN Edginton Pharmaceutics 9 (4), 47, 2017 | 30 | 2017 |
Development and Validation of a Population-Pharmacokinetic Model for Rurioctacog Alfa Pegol (Adynovate®): A Report on Behalf of the WAPPS-Hemo … P Chelle, CHT Yeung, SE Croteau, J Lissick, V Balasa, C Ashburner, ... Clinical pharmacokinetics 59, 245-256, 2020 | 23 | 2020 |
Tissue factor pathway inhibitor is the main determinant of thrombin generation in haemophilic patients P Chelle, A Montmartin, P Damien, M Piot, M Cournil, A Lienhart, ... Haemophilia 25 (2), 343-348, 2019 | 23 | 2019 |
Prediction of individual factor VIII or IX level for the correction of thrombin generation in haemophilic patients P Chelle, A Montmartin, M Piot, L Ardillon, B Wibaut, B Frotscher, ... Haemophilia 24 (6), 995-1001, 2018 | 18 | 2018 |
Terminal half‐life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database O Versloot, E Iserman, P Chelle, F Germini, AN Edginton, REG Schutgens, ... Journal of Thrombosis and Haemostasis 19 (8), 1896-1906, 2021 | 16 | 2021 |
Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients P Chelle, CHT Yeung, S Bonanad, JC Morales Muñoz, MC Ozelo, ... Journal of pharmacokinetics and pharmacodynamics 46, 427-438, 2019 | 14 | 2019 |
Multicentre pharmacokinetic evaluation of rFVIII‐Fc (efmoroctocog alfa) in a real life and comparison with non‐extended half‐life FVIII concentrates C Pouplard, L Sattler, A Ryman, V Eschwege, E De Maistre, C Flaujac, ... Haemophilia 26 (2), 282-289, 2020 | 13 | 2020 |
Patient-specific modelling of blood coagulation N Ratto, A Bouchnita, P Chelle, M Marion, M Panteleev, D Nechipurenko, ... Bulletin of Mathematical Biology 83, 1-31, 2021 | 12 | 2021 |
A novel, enriched population pharmacokinetic model for recombinant factor VIII-Fc fusion protein concentrate in hemophilia A patients LH Bukkems, JM Heijdra, M Mathias, PW Collins, CRM Hay, RC Tait, ... Thrombosis and haemostasis 120 (05), 747-757, 2020 | 11 | 2020 |
Clustering of thrombin generation test data using a reduced mathematical model of blood coagulation N Ratto, A Tokarev, P Chelle, B Tardy-Poncet, V Volpert Acta Biotheoretica 68, 21-43, 2020 | 11 | 2020 |
Pediatric dose selection for therapeutic proteins PRV Malik, ZH Temrikar, P Chelle, AN Edginton, B Meibohm The Journal of Clinical Pharmacology 61, S193-S206, 2021 | 10 | 2021 |
Pharmacokinetic implications of dosing emicizumab based on vial size: A simulation study JK Yu, A Iorio, P Chelle, AN Edginton Haemophilia 27 (3), 358-365, 2021 | 10 | 2021 |
Body mass index best predicts recovery of recombinant factor VIII in underweight to obese patients with severe haemophilia A A Tiede, AR Cid, G Goldmann, V Jiménez-Yuste, M Pluta, T Lissitchkov, ... Thrombosis and Haemostasis 120 (02), 277-288, 2020 | 9 | 2020 |
Evaluation and calibration of in silico models of thrombin generation using experimental data from healthy and haemophilic subjects P Chelle, C Morin, A Montmartin, M Piot, M Cournil, B Tardy-Poncet Bulletin of Mathematical Biology 80, 1989-2025, 2018 | 9 | 2018 |
A method for the quantitative extraction of gold nanoparticles from human bronchoalveolar lavage fluids through a glycerol gradient D Bitounis, V Barnier, C Guibert, J Pourchez, V Forest, D Boudard, ... Nanoscale 10 (6), 2955-2969, 2018 | 9 | 2018 |
Limited sampling strategies for accurate determination of extended half‐life factor VIII pharmacokinetics in severe haemophilia A patients A McEneny‐King, P Chelle, MH Goggans, PJ Barker, TW Jacobs, ... Haemophilia 27 (3), 408-416, 2021 | 7 | 2021 |