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Pierre Chelle
Pierre Chelle
Post doctoral fellow, School of Pharmacy, University of Waterloo
Adresse e-mail validée de uwaterloo.ca - Page d'accueil
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Année
Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?
MD Carcao, P Chelle, E Clarke, L Kim, L Tiseo, M Morfini, T Hossain, ...
Journal of Thrombosis and Haemostasis 17 (7), 1085-1096, 2019
402019
Development and evaluation of the population pharmacokinetic models for FVIII and FIX concentrates of the WAPPS‐Hemo project
DM Hajducek, P Chelle, C Hermans, A Iorio, A McEneny‐King, J Yu, ...
Haemophilia 26 (3), 384-400, 2020
372020
Biodistribution and physiologically-based pharmacokinetic modeling of gold nanoparticles in mice with interspecies extrapolation
M Aborig, PRV Malik, S Nambiar, P Chelle, J Darko, A Mutsaers, ...
Pharmaceutics 11 (4), 179, 2019
372019
Development and evaluation of a generic population pharmacokinetic model for standard half-life factor VIII for use in dose individualization
A McEneny-King, P Chelle, G Foster, A Keepanasseril, A Iorio, ...
Journal of Pharmacokinetics and Pharmacodynamics 46, 411-426, 2019
362019
Modeling of body weight metrics for effective and cost-efficient conventional factor VIII dosing in hemophilia A prophylaxis
A McEneny-King, P Chelle, S Henrard, C Hermans, A Iorio, AN Edginton
Pharmaceutics 9 (4), 47, 2017
302017
Development and Validation of a Population-Pharmacokinetic Model for Rurioctacog Alfa Pegol (Adynovate®): A Report on Behalf of the WAPPS-Hemo …
P Chelle, CHT Yeung, SE Croteau, J Lissick, V Balasa, C Ashburner, ...
Clinical pharmacokinetics 59, 245-256, 2020
232020
Tissue factor pathway inhibitor is the main determinant of thrombin generation in haemophilic patients
P Chelle, A Montmartin, P Damien, M Piot, M Cournil, A Lienhart, ...
Haemophilia 25 (2), 343-348, 2019
232019
Prediction of individual factor VIII or IX level for the correction of thrombin generation in haemophilic patients
P Chelle, A Montmartin, M Piot, L Ardillon, B Wibaut, B Frotscher, ...
Haemophilia 24 (6), 995-1001, 2018
182018
Terminal half‐life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database
O Versloot, E Iserman, P Chelle, F Germini, AN Edginton, REG Schutgens, ...
Journal of Thrombosis and Haemostasis 19 (8), 1896-1906, 2021
162021
Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients
P Chelle, CHT Yeung, S Bonanad, JC Morales Muñoz, MC Ozelo, ...
Journal of pharmacokinetics and pharmacodynamics 46, 427-438, 2019
142019
Multicentre pharmacokinetic evaluation of rFVIII‐Fc (efmoroctocog alfa) in a real life and comparison with non‐extended half‐life FVIII concentrates
C Pouplard, L Sattler, A Ryman, V Eschwege, E De Maistre, C Flaujac, ...
Haemophilia 26 (2), 282-289, 2020
132020
Patient-specific modelling of blood coagulation
N Ratto, A Bouchnita, P Chelle, M Marion, M Panteleev, D Nechipurenko, ...
Bulletin of Mathematical Biology 83, 1-31, 2021
122021
A novel, enriched population pharmacokinetic model for recombinant factor VIII-Fc fusion protein concentrate in hemophilia A patients
LH Bukkems, JM Heijdra, M Mathias, PW Collins, CRM Hay, RC Tait, ...
Thrombosis and haemostasis 120 (05), 747-757, 2020
112020
Clustering of thrombin generation test data using a reduced mathematical model of blood coagulation
N Ratto, A Tokarev, P Chelle, B Tardy-Poncet, V Volpert
Acta Biotheoretica 68, 21-43, 2020
112020
Pediatric dose selection for therapeutic proteins
PRV Malik, ZH Temrikar, P Chelle, AN Edginton, B Meibohm
The Journal of Clinical Pharmacology 61, S193-S206, 2021
102021
Pharmacokinetic implications of dosing emicizumab based on vial size: A simulation study
JK Yu, A Iorio, P Chelle, AN Edginton
Haemophilia 27 (3), 358-365, 2021
102021
Body mass index best predicts recovery of recombinant factor VIII in underweight to obese patients with severe haemophilia A
A Tiede, AR Cid, G Goldmann, V Jiménez-Yuste, M Pluta, T Lissitchkov, ...
Thrombosis and Haemostasis 120 (02), 277-288, 2020
92020
Evaluation and calibration of in silico models of thrombin generation using experimental data from healthy and haemophilic subjects
P Chelle, C Morin, A Montmartin, M Piot, M Cournil, B Tardy-Poncet
Bulletin of Mathematical Biology 80, 1989-2025, 2018
92018
A method for the quantitative extraction of gold nanoparticles from human bronchoalveolar lavage fluids through a glycerol gradient
D Bitounis, V Barnier, C Guibert, J Pourchez, V Forest, D Boudard, ...
Nanoscale 10 (6), 2955-2969, 2018
92018
Limited sampling strategies for accurate determination of extended half‐life factor VIII pharmacokinetics in severe haemophilia A patients
A McEneny‐King, P Chelle, MH Goggans, PJ Barker, TW Jacobs, ...
Haemophilia 27 (3), 408-416, 2021
72021
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