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Anna Bigas
Anna Bigas
Group Leader and Coordinator, Stem Cells and Cancer group. Research Institute Hospital del Mar and
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Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals
M Shan, M Gentile, JR Yeiser, AC Walland, VU Bornstein, K Chen, B He, ...
Science 342 (6157), 447-453, 2013
6352013
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer
V Rodilla, A Villanueva, A Obrador-Hevia, À Robert-Moreno, ...
Proceedings of the National Academy of Sciences 106 (15), 6315-6320, 2009
4392009
Phosphorylation by glycogen synthase kinase-3β down-regulates Notch activity, a link for Notch and Wnt pathways
L Espinosa, J Inglés-Esteve, C Aguilera, A Bigas
Journal of Biological Chemistry 278 (34), 32227-32235, 2003
4142003
Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation
LA Milner, A Bigas
Blood, The Journal of the American Society of Hematology 93 (8), 2431-2448, 1999
4131999
RBPJκ-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus
O Ehm, C Göritz, M Covic, I Schäffner, TJ Schwarz, E Karaca, B Kempkes, ...
Journal of Neuroscience 30 (41), 13794-13807, 2010
3672010
Blood development: hematopoietic stem cell dependence and independence
E Dzierzak, A Bigas
Cell stem cell 22 (5), 639-651, 2018
3472018
RBPjκ-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
À Robert-Moreno, L Espinosa, JL de la Pompa, A Bigas
Oxford University Press for The Company of Biologists Limited 132 (5), 1117-1126, 2005
3472005
The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia
L Espinosa, S Cathelin, T D'Altri, T Trimarchi, A Statnikov, J Guiu, ...
Cancer cell 18 (3), 268-281, 2010
3342010
Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines
A Bigas, DIK Martin, LA Milner
Molecular and cellular biology 18 (4), 2324-2333, 1998
2841998
Inhibition of granulocytic differentiation by mNotch1
LA Milner, A Bigas, R Kopan, C Brashem-Stein, ID Bernstein, DIK Martin
Proceedings of the National Academy of Sciences 93 (23), 13014-13019, 1996
2441996
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1
À Robert‐Moreno, J Guiu, C Ruiz‐Herguido, ME López, J Inglés‐Esteve, ...
The EMBO journal 27 (13), 1886-1895, 2008
2292008
Hematopoietic stem cells: to be or Notch to be
A Bigas, L Espinosa
Blood, The Journal of the American Society of Hematology 119 (14), 3226-3235, 2012
2182012
The association of Notch2 and NF-κB accelerates RANKL-induced osteoclastogenesis
H Fukushima, A Nakao, F Okamoto, M Shin, H Kajiya, S Sakano, A Bigas, ...
Molecular and cellular biology, 2008
1982008
Notch signal strength controls cell fate in the haemogenic endothelium
L Gama-Norton, E Ferrando, C Ruiz-Herguido, Z Liu, J Guiu, AB Islam, ...
Nature communications 6 (1), 8510, 2015
1672015
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer
V Fernandez-Majada, C Aguilera, A Villanueva, F Vilardell, ...
Proceedings of the National Academy of Sciences 104 (1), 276-281, 2007
1672007
Recruitment of IκBα to the hes1 promoter is associated with transcriptional repression
C Aguilera, R Hoya-Arias, G Haegeman, L Espinosa, A Bigas
Proceedings of the National Academy of Sciences 101 (47), 16537-16542, 2004
1662004
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling
J Guiu, R Shimizu, T D’Altri, ST Fraser, J Hatakeyama, EH Bresnick, ...
Journal of Experimental Medicine 210 (1), 71-84, 2013
1432013
Hematopoietic stem cell development requires transient Wnt/β-catenin activity
C Ruiz-Herguido, J Guiu, T D'Altri, J Inglés-Esteve, E Dzierzak, ...
Journal of Experimental Medicine 209 (8), 1457-1468, 2012
1432012
IκBα and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFκB pathways
L Espinosa, J Inglés-Esteve, A Robert-Moreno, A Bigas
Molecular biology of the cell 14 (2), 491-502, 2003
1332003
Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice
J Farrés, J Martín-Caballero, C Martínez, JJ Lozano, L Llacuna, ...
Blood, The Journal of the American Society of Hematology 122 (1), 44-54, 2013
1202013
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