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Lei Gu
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" Circlize" implements and enhances circular visualization in R
Z Gu, L Gu, R Eils, M Schlesner, B Brors
28942014
DNA methylation on N6-adenine in C. elegans
EL Greer, MA Blanco, L Gu, E Sendinc, J Liu, D Aristizábal-Corrales, ...
Cell 161 (4), 868-878, 2015
7112015
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
6312014
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ...
Cell stem cell 15 (4), 507-522, 2014
5612014
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer
J Weischenfeldt, R Simon, L Feuerbach, K Schlangen, D Weichenhan, ...
Cancer cell 23 (2), 159-170, 2013
3992013
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ...
Nature genetics 48 (3), 253-264, 2016
3192016
TRIM24 is an oncogenic transcriptional activator in prostate cancer
AC Groner, L Cato, J de Tribolet-Hardy, T Bernasocchi, H Janouskova, ...
Cancer cell 29 (6), 846-858, 2016
2542016
Tagmentation-based whole-genome bisulfite sequencing
Q Wang, L Gu, A Adey, B Radlwimmer, W Wang, V Hovestadt, M Bähr, ...
Nature protocols 8 (10), 2022-2032, 2013
1792013
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia
CC Oakes, R Claus, L Gu, Y Assenov, J Hüllein, M Zucknick, M Bieg, ...
Cancer discovery 4 (3), 348-361, 2014
1612014
Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia
C Baer, R Claus, LP Frenzel, M Zucknick, YJ Park, L Gu, D Weichenhan, ...
Cancer research 72 (15), 3775-3785, 2012
1582012
Suppression of enhancer overactivation by a RACK7-histone demethylase complex
H Shen, W Xu, R Guo, B Rong, L Gu, Z Wang, C He, L Zheng, X Hu, Z Hu, ...
Cell 165 (2), 331-342, 2016
1572016
BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence
L Gu, SC Frommel, CC Oakes, R Simon, K Grupp, CY Gerig, D Bär, ...
Nature genetics 47 (1), 22-30, 2015
1442015
Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway
B Goeppert, C Konermann, CR Schmidt, O Bogatyrova, L Geiselhart, ...
Hepatology 59 (2), 544-554, 2014
1292014
A mouse model of X-linked intellectual disability associated with impaired removal of histone methylation
S Iwase, E Brookes, S Agarwal, AI Badeaux, H Ito, CN Vallianatos, ...
Cell reports 14 (5), 1000-1009, 2016
1222016
Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
T Bauer, S Trump, N Ishaque, L Thürmann, L Gu, M Bauer, M Bieg, Z Gu, ...
Molecular Systems Biology 12 (3), 861, 2016
1192016
Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications
S Jahreis, S Trump, M Bauer, T Bauer, L Thürmann, R Feltens, Q Wang, ...
Journal of Allergy and Clinical Immunology 141 (2), 741-753, 2018
1052018
METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing
H Chen, L Gu, EA Orellana, Y Wang, J Guo, QI Liu, L Wang, Z Shen, H Wu, ...
Cell research 30 (6), 544-547, 2020
1022020
Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma
CH Shen, SH Kim, S Trousil, DT Frederick, A Piris, P Yuan, L Cai, L Gu, ...
Nature medicine 22 (9), 1056-1061, 2016
822016
Enhancer-mediated oncogenic function of the menin tumor suppressor in breast cancer
KMA Dreijerink, AC Groner, ESM Vos, A Font-Tello, L Gu, D Chi, J Reyes, ...
Cell reports 18 (10), 2359-2372, 2017
732017
Integrative analysis defines distinct prognostic subgroups of intrahepatic cholangiocarcinoma
B Goeppert, R Toth, S Singer, T Albrecht, DB Lipka, P Lutsik, D Brocks, ...
Hepatology 69 (5), 2091-2106, 2019
712019
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