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Margarita Tararina
Margarita Tararina
Postdoctoral Researcher, University of Pennsylvania
Verified email at sas.upenn.edu - Homepage
Title
Cited by
Cited by
Year
Targeted deletion of kynurenine 3-Monooxygenase in mice a new tool for studying kynurenine pathway metabolism in periphery and brain
F Giorgini, SY Huang, KV Sathyasaikumar, FM Notarangelo, ...
Journal of Biological Chemistry 288 (51), 36554-36566, 2013
1262013
Xanthurenic acid formation from 3-hydroxykynurenine in the mammalian brain: neurochemical characterization and physiological effects
KV Sathyasaikumar, M Tararina, HQ Wu, SA Neale, F Weisz, TE Salt, ...
Neuroscience 367, 85-97, 2017
452017
Structural Analysis Provides Mechanistic Insight into Nicotine Oxidoreductase from Pseudomonas putida
MA Tararina, KD Janda, KN Allen
Biochemistry 55 (48), 6595-6598, 2016
282016
Bioinformatic Analysis of the Flavin-Dependent Amine Oxidase Superfamily: Adaptations for Substrate Specificity and Catalytic Diversity
MA Tararina, KN Allen
Journal of Molecular Biology, 2020
222020
Crystallography coupled with kinetic analysis provides mechanistic underpinnings of a nicotine-degrading enzyme
MA Tararina, S Xue, LC Smith, SN Muellers, PO Miranda, KD Janda, ...
Biochemistry 57 (26), 3741-3751, 2018
212018
Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A
L Lin, ME Olson, T Sugane, LD Turner, MA Tararina, AL Nielsen, ...
Journal of Medicinal Chemistry 63 (19), 11100-11120, 2020
182020
2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: a step toward new antiexcitotoxic agents
GP Vallerini, L Amori, C Beato, M Tararina, XD Wang, R Schwarcz, ...
Journal of medicinal chemistry 56 (23), 9482-9495, 2013
172013
Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2
MA Tararina, KK Dam, M Dhingra, KD Janda, BA Palfey, KN Allen
Biochemistry 60 (4), 259-273, 2021
102021
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation
L Sinatra, A Vogelmann, F Friedrich, MA Tararina, E Neuwirt, A Colcerasa, ...
Journal of Medicinal Chemistry 66 (21), 14787-14814, 2023
32023
Structural Insights into the Substrate Range of a Bacterial Monoamine Oxidase
SN Muellers, MA Tararina, U Kuzmanovic, JE Galagan, KN Allen
Biochemistry 62 (3), 851-862, 2023
32023
Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C–N Bond-Forming Reaction of Flavunoidine Biosynthesis
MA Tararina, DA Yee, Y Tang, DW Christianson
Biochemistry 61 (18), 2014-2024, 2022
12022
Enzyme-based electrochemical nicotine biosensor
J Galagan, MW Grinstaff, U Kuzmanovic, C Mingfu, MA Tararina, KN Allen
US Patent 11,331,020, 2022
12022
Structural Analysis of a Non‐canonical Terpene Synthase
MA Tararina, DA Yee, Y Tang, DW Christianson
The FASEB Journal 36, 2022
2022
An Enzymatic Electrochemical Biosensor for Real-Time Detection of Physiologically Relevant Nicotine Concentrations
U Kuzmanovic, M Chen, M Tararina, N Shu, P Sensharma, A Gupta, ...
Electrochemical Society Meeting Abstracts prime2020, 3374-3374, 2020
2020
Structural and mechanistic analyses of a nicotine-degrading enzyme from Pseudomonas putida: towards design of tools and biotherapeutics
MA Tararina
Boston University, 2020
2020
An enzymatic electrochemical biosensor for real-time nicotine detection
U Kuzmanovic, M Chen, M Tararina, N Shu, A Balijepalli, M Zamani, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Structure/Function Analysis of Pseudomonas putida Nicotine Oxidoreductase
M Tararina, S Xue, K Janda, K Allen
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, A255-A255, 2017
2017
Kynurenine Pathway Metabolites as Modulators of Glutamatergic Neurotransmission
R Schwarcz, KV Sathyasaikumar, M Tararina, HQ Wu, DM Bortz, JP Bruno
CURRENT NEUROPHARMACOLOGY 12, 55-55, 2014
2014
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Articles 1–18