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Jiqiang Ling
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Aminoacyl-tRNA synthesis and translational quality control
J Ling, N Reynolds, M Ibba
Annual review of microbiology 63, 61-78, 2009
4372009
Exome sequencing and the management of neurometabolic disorders
M Tarailo-Graovac, C Shyr, CJ Ross, GA Horvath, R Salvarinova, XC Ye, ...
New England Journal of Medicine 374 (23), 2246-2255, 2016
3112016
Severe oxidative stress induces protein mistranslation through impairment of an aminoacyl-tRNA synthetase editing site
J Ling, D Söll
Proceedings of the National Academy of Sciences 107 (9), 4028-4033, 2010
2532010
Post-transfer editing in vitro and in vivo by the β subunit of phenylalanyl-tRNA synthetase
H Roy, J Ling, M Irnov, M Ibba
The EMBO journal 23 (23), 4639-4648, 2004
1922004
Upgrading protein synthesis for synthetic biology
P O'donoghue, J Ling, YS Wang, D Söll
Nature chemical biology 9 (10), 594-598, 2013
1782013
Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures
X Zhang, J Ling, G Barcia, L Jing, J Wu, BJ Barry, GH Mochida, RS Hill, ...
The American Journal of Human Genetics 94 (4), 547-558, 2014
1482014
Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase
H Roy, J Ling, J Alfonzo, M Ibba
Journal of Biological Chemistry 280 (46), 38186-38192, 2005
1272005
Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology
J Ling, P O'donoghue, D Söll
Nature Reviews Microbiology 13 (11), 707-721, 2015
1262015
Protein aggregation caused by aminoglycoside action is prevented by a hydrogen peroxide scavenger
J Ling, C Cho, LT Guo, HR Aerni, J Rinehart, D Söll
Molecular cell 48 (5), 713-722, 2012
1242012
Resampling and editing of mischarged tRNA prior to translation elongation
J Ling, BR So, SS Yadavalli, H Roy, S Shoji, K Fredrick, K Musier-Forsyth, ...
Molecular cell 33 (5), 654-660, 2009
1232009
Mechanism of tRNA-dependent editing in translational quality control
J Ling, H Roy, M Ibba
Proceedings of the National Academy of Sciences 104 (1), 72, 2007
1042007
Cell-specific differences in the requirements for translation quality control
NM Reynolds, J Ling, H Roy, R Banerjee, SE Repasky, P Hamel, M Ibba
Proceedings of the National Academy of Sciences 107 (9), 4063-4068, 2010
942010
Near-cognate suppression of amber, opal and quadruplet codons competes with aminoacyl-tRNAPyl for genetic code expansion
P O’Donoghue, L Prat, IU Heinemann, J Ling, K Odoi, WR Liu, D Söll
FEBS letters 586 (21), 3931-3937, 2012
922012
Protein mistranslation protects bacteria against oxidative stress
Y Fan, J Wu, MH Ung, N De Lay, C Cheng, J Ling
Nucleic acids research 43 (3), 1740-1748, 2015
902015
Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine
J Ling, SS Yadavalli, M Ibba
Rna 13 (11), 1881-1886, 2007
752007
Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers
Z Zhang, Y Ye, J Gong, H Ruan, CJ Liu, Y Xiang, C Cai, AY Guo, J Ling, ...
Communications Biology 1 (1), 234, 2018
682018
Deficient activity of alanyl‐tRNA synthetase underlies an autosomal recessive syndrome of progressive microcephaly, hypomyelination, and epileptic encephalopathy
T Nakayama, J Wu, P Galvin‐Parton, J Weiss, MR Andriola, RS Hill, ...
Human mutation 38 (10), 1348-1354, 2017
592017
Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome
J Ling, H Roy, D Qin, MAT Rubio, JD Alfonzo, K Fredrick, M Ibba
Proceedings of the National Academy of Sciences 104 (39), 15299-15304, 2007
562007
The mechanism of pre-transfer editing in yeast mitochondrial threonyl-tRNA synthetase
J Ling, KM Peterson, I Simonović, D Söll, M Simonović
Journal of Biological Chemistry 287 (34), 28518-28525, 2012
502012
Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase
J Wu, Y Fan, J Ling
Nucleic acids research 42 (10), 6523-6531, 2014
482014
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Articles 1–20