Structural insights into PROTAC-mediated degradation of Bcl-xL C Chung, H Dai, E Fernandez, CP Tinworth, I Churcher, J Cryan, ... ACS Chemical Biology 15 (9), 2316-2323, 2020 | 59 | 2020 |
Targeting endogenous K-RAS for degradation through the affinity-directed protein missile system S Röth, TJ Macartney, A Konopacka, KH Chan, H Zhou, MA Queisser, ... Cell Chemical Biology 27 (9), 1151-1163. e6, 2020 | 52 | 2020 |
Osmoregulation requires brain expression of the renal Na-K-2Cl cotransporter NKCC2 A Konopacka, J Qiu, ST Yao, MP Greenwood, M Greenwood, T Lancaster, ... Journal of Neuroscience 35 (13), 5144-5155, 2015 | 48 | 2015 |
The hypothalamic‐neurohypophyseal system: from genome to physiology D Murphy, A Konopacka, C Hindmarch, JFR Paton, JV Sweedler, ... Journal of neuroendocrinology 24 (4), 539-553, 2012 | 43 | 2012 |
An intracellular allosteric modulator binding pocket in SK2 ion channels is shared by multiple chemotypes LTY Cho, AJ Alexandrou, R Torella, J Knafels, J Hobbs, T Taylor, A Loucif, ... Structure 26 (4), 533-544. e3, 2018 | 29 | 2018 |
RNA binding protein Caprin-2 is a pivotal regulator of the central osmotic defense response A Konopacka, M Greenwood, SY Loh, J Paton, D Murphy Elife 4, e09656, 2015 | 29 | 2015 |
Protein kinase G is involved in ammonia‐induced swelling of astrocytes A Konopacka, FA Konopacki, J Albrecht Journal of neurochemistry 109, 246-251, 2009 | 26 | 2009 |
Ammonia inhibits the C-type natriuretic peptide-dependent cyclic GMP synthesis and calcium accumulation in a rat brain endothelial cell line A Konopacka, M Zielińska, J Albrecht Neurochemistry international 52 (6), 1160-1166, 2008 | 21 | 2008 |
Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices M Zielińska, I Fresko, A Konopacka, V Felipo, J Albrecht Neurotoxicology 28 (6), 1260-1263, 2007 | 17 | 2007 |
Transcriptional and post-transcriptional regulation of oxytocin and vasopressin gene expression by CREB3L1 and CAPRIN2 S Bárez-López, A Konopacka, SJ Cross, M Greenwood, M Skarveli, ... Neuroendocrinology 112 (11), 1058-1077, 2022 | 12 | 2022 |
Ammonia affects the activity and expression of soluble and particulate GC in cultured rat astrocytes A Konopacka, I Fręśko, S Piaskowski, J Albrecht, M Zielińska Neurochemistry international 48 (6-7), 553-558, 2006 | 9 | 2006 |
Unsupervised network analysis of the plastic supraoptic nucleus transcriptome predicts caprin2 regulatory interactions SY Loh, T Jahans-Price, MP Greenwood, M Greenwood, SZ Hoe, ... Eneuro 4 (6), 2017 | 6 | 2017 |
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3 S Röth, NM Kocaturk, PS Sathyamurthi, B Carton, M Watt, TJ Macartney, ... Cell Chemical Biology 30 (10), 1261-1276. e7, 2023 | 5 | 2023 |
Screening of E3 ligases uncovers KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin and FoxP3 S Röth, B Carton, PS Sathyamurthi, M Watt, TJ Macartney, KH Chan, ... STK33, β-catenin and FoxP3, 2022 | 1 | 2022 |
A phenotypic approach for the identification of new molecules for targeted protein degradation applications P Stacey, H Lithgow, X Lewell, A Konopacka, S Besley, G Green, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (7), 885-895, 2021 | 1 | 2021 |
Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells PJ Brennan, RE Saunders, M Spanou, M Serafini, L Sun, GP Heger, ... bioRxiv, 2024.03. 15.585309, 2024 | | 2024 |
Abstract B34: Targeted destruction of endogenous K-RAS using an Affinity directed PROtein Missile (AdPROM) SOM Roth, TJ Macartney, A Konopacka, M Queisser, GP Sapkota Molecular Cancer Research 18 (5_Supplement), B34-B34, 2020 | | 2020 |
Targeted destruction of endogenous K-RAS using an Affinity directed PROtein Missile (AdPROM). SOM Roth, TJ Macartney, A Konopacka, M Queisser, GP Sapkota MOLECULAR CANCER RESEARCH 18 (5), 69-69, 2020 | | 2020 |
Ammonia inhibits particulate guanylate cyclase-dependent cGMP formation and calcium transport in a rat brain endothelial cell line A Konopacka, M Zielinska, L Fresko, J Albrecht Acta Neurobiologiae Experimentalis 66 (4), 2006 | | 2006 |
A two-stage response of the nitric oxide/cyclic GMP pathway in cultured rat astrocytes treated with ammonia A Konopacka, M Zielinska, M Aschner, J Albrecht JOURNAL OF NEUROCHEMISTRY 94, 98-98, 2005 | | 2005 |