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Agnieszka Konopacka
Agnieszka Konopacka
In Vitro Biologist, GSK
Verified email at gsk.com
Title
Cited by
Cited by
Year
Structural insights into PROTAC-mediated degradation of Bcl-xL
C Chung, H Dai, E Fernandez, CP Tinworth, I Churcher, J Cryan, ...
ACS Chemical Biology 15 (9), 2316-2323, 2020
592020
Targeting endogenous K-RAS for degradation through the affinity-directed protein missile system
S Röth, TJ Macartney, A Konopacka, KH Chan, H Zhou, MA Queisser, ...
Cell Chemical Biology 27 (9), 1151-1163. e6, 2020
522020
Osmoregulation requires brain expression of the renal Na-K-2Cl cotransporter NKCC2
A Konopacka, J Qiu, ST Yao, MP Greenwood, M Greenwood, T Lancaster, ...
Journal of Neuroscience 35 (13), 5144-5155, 2015
482015
The hypothalamic‐neurohypophyseal system: from genome to physiology
D Murphy, A Konopacka, C Hindmarch, JFR Paton, JV Sweedler, ...
Journal of neuroendocrinology 24 (4), 539-553, 2012
432012
An intracellular allosteric modulator binding pocket in SK2 ion channels is shared by multiple chemotypes
LTY Cho, AJ Alexandrou, R Torella, J Knafels, J Hobbs, T Taylor, A Loucif, ...
Structure 26 (4), 533-544. e3, 2018
292018
RNA binding protein Caprin-2 is a pivotal regulator of the central osmotic defense response
A Konopacka, M Greenwood, SY Loh, J Paton, D Murphy
Elife 4, e09656, 2015
292015
Protein kinase G is involved in ammonia‐induced swelling of astrocytes
A Konopacka, FA Konopacki, J Albrecht
Journal of neurochemistry 109, 246-251, 2009
262009
Ammonia inhibits the C-type natriuretic peptide-dependent cyclic GMP synthesis and calcium accumulation in a rat brain endothelial cell line
A Konopacka, M Zielińska, J Albrecht
Neurochemistry international 52 (6), 1160-1166, 2008
212008
Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices
M Zielińska, I Fresko, A Konopacka, V Felipo, J Albrecht
Neurotoxicology 28 (6), 1260-1263, 2007
172007
Transcriptional and post-transcriptional regulation of oxytocin and vasopressin gene expression by CREB3L1 and CAPRIN2
S Bárez-López, A Konopacka, SJ Cross, M Greenwood, M Skarveli, ...
Neuroendocrinology 112 (11), 1058-1077, 2022
122022
Ammonia affects the activity and expression of soluble and particulate GC in cultured rat astrocytes
A Konopacka, I Fręśko, S Piaskowski, J Albrecht, M Zielińska
Neurochemistry international 48 (6-7), 553-558, 2006
92006
Unsupervised network analysis of the plastic supraoptic nucleus transcriptome predicts caprin2 regulatory interactions
SY Loh, T Jahans-Price, MP Greenwood, M Greenwood, SZ Hoe, ...
Eneuro 4 (6), 2017
62017
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
S Röth, NM Kocaturk, PS Sathyamurthi, B Carton, M Watt, TJ Macartney, ...
Cell Chemical Biology 30 (10), 1261-1276. e7, 2023
52023
Screening of E3 ligases uncovers KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin and FoxP3
S Röth, B Carton, PS Sathyamurthi, M Watt, TJ Macartney, KH Chan, ...
STK33, β-catenin and FoxP3, 2022
12022
A phenotypic approach for the identification of new molecules for targeted protein degradation applications
P Stacey, H Lithgow, X Lewell, A Konopacka, S Besley, G Green, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (7), 885-895, 2021
12021
Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells
PJ Brennan, RE Saunders, M Spanou, M Serafini, L Sun, GP Heger, ...
bioRxiv, 2024.03. 15.585309, 2024
2024
Abstract B34: Targeted destruction of endogenous K-RAS using an Affinity directed PROtein Missile (AdPROM)
SOM Roth, TJ Macartney, A Konopacka, M Queisser, GP Sapkota
Molecular Cancer Research 18 (5_Supplement), B34-B34, 2020
2020
Targeted destruction of endogenous K-RAS using an Affinity directed PROtein Missile (AdPROM).
SOM Roth, TJ Macartney, A Konopacka, M Queisser, GP Sapkota
MOLECULAR CANCER RESEARCH 18 (5), 69-69, 2020
2020
Ammonia inhibits particulate guanylate cyclase-dependent cGMP formation and calcium transport in a rat brain endothelial cell line
A Konopacka, M Zielinska, L Fresko, J Albrecht
Acta Neurobiologiae Experimentalis 66 (4), 2006
2006
A two-stage response of the nitric oxide/cyclic GMP pathway in cultured rat astrocytes treated with ammonia
A Konopacka, M Zielinska, M Aschner, J Albrecht
JOURNAL OF NEUROCHEMISTRY 94, 98-98, 2005
2005
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