ivan topisirovic
ivan topisirovic
Associate Professor, McGill
Adresse e-mail validée de mcgill.ca - Page d'accueil
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
MJA DJ Klionsky, K Abdelmohsen, A Abe
Autophagy 12 (1), 2016
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
RJO Dowling, I Topisirovic, T Alain, M Bidinosti, BD Fonseca, ...
Science 328 (5982), 1172-1176, 2010
Targeting the translation machinery in cancer
M Bhat, N Robichaud, L Hulea, N Sonenberg, J Pelletier, I Topisirovic
Nature reviews Drug discovery 14 (4), 261-278, 2015
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
M Morita, SP Gravel, V Chénard, K Sikström, L Zheng, T Alain, V Gandin, ...
Cell metabolism 18 (5), 698-711, 2013
Dissecting the role of mTOR: lessons from mTOR inhibitors
RJO Dowling, I Topisirovic, BD Fonseca, N Sonenberg
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 433-439, 2010
Cap and cap‐binding proteins in the control of gene expression
I Topisirovic, YV Svitkin, N Sonenberg, AJ Shatkin
Wiley Interdisciplinary Reviews: RNA 2 (2), 277-298, 2011
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
M Morita, SP Gravel, L Hulea, O Larsson, M Pollak, J St-Pierre, ...
Cell cycle 14 (4), 473-480, 2015
eIF4E is a central node of an RNA regulon that governs cellular proliferation
B Culjkovic, I Topisirovic, L Skrabanek, M Ruiz-Gutierrez, KLB Borden
Journal of Cell Biology 175 (3), 415-426, 2006
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
I Topisirovic, M Ruiz-Gutierrez, KLB Borden
Cancer research 64 (23), 8639-8642, 2004
Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap
A Kentsis, I Topisirovic, B Culjkovic, L Shao, KLB Borden
Proceedings of the National Academy of Sciences 101 (52), 18105-18110, 2004
Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis
I Topisirovic, ML Guzman, MJ McConnell, JD Licht, B Culjkovic, ...
Molecular and cellular biology 23 (24), 8992-9002, 2003
eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′ UTR
B Culjkovic, I Topisirovic, L Skrabanek, M Ruiz-Gutierrez, KLB Borden
The Journal of cell biology 169 (2), 245-256, 2005
Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E
B Culjkovic, I Topisirovic, KLB Borden
Cell cycle 6 (1), 65-69, 2007
Regulation of mRNA translation by signaling pathways
PP Roux, I Topisirovic
Cold Spring Harbor perspectives in biology 4 (11), a012252, 2012
S6K1 plays a critical role in early adipocyte differentiation
LS Carnevalli, K Masuda, F Frigerio, O Le Bacquer, SH Um, V Gandin, ...
Developmental cell 18 (5), 763-774, 2010
Distinct perturbation of the translatome by the antidiabetic drug metformin
O Larsson, M Morita, I Topisirovic, T Alain, MJ Blouin, M Pollak, ...
Proceedings of the National Academy of Sciences 109 (23), 8977-8982, 2012
The proline‐rich homeodomain protein, PRH, is a tissue‐specific inhibitor of eIF4E‐dependent cyclin D1 mRNA transport and growth
I Topisirovic, B Culjkovic, N Cohen, JM Perez, L Skrabanek, KLB Borden
The EMBO journal 22 (3), 689-703, 2003
Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection
M Jaramillo, MA Gomez, O Larsson, MT Shio, I Topisirovic, I Contreras, ...
Cell host & microbe 9 (4), 331-341, 2011
Translational control of immune responses: from transcripts to translatomes
CA Piccirillo, E Bjur, I Topisirovic, N Sonenberg, O Larsson
Nature immunology 15 (6), 503-511, 2014
mTOR controls mitochondrial dynamics and cell survival via MTFP1
M Morita, J Prudent, K Basu, V Goyon, S Katsumura, L Hulea, D Pearl, ...
Molecular cell 67 (6), 922-935. e5, 2017
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