Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke G Szalay, B Martinecz, N Lénárt, Z Környei, B Orsolits, L Judák, E Császár, ... Nature communications 7 (1), 11499, 2016 | 549 | 2016 |
Microglia monitor and protect neuronal function through specialized somatic purinergic junctions C Cserép, B Pósfai, N Lénárt, R Fekete, ZI László, Z Lele, B Orsolits, ... Science 367 (6477), 528-537, 2020 | 487 | 2020 |
Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production A Houlden, M Goldrick, D Brough, ES Vizi, N Lénárt, B Martinecz, ... Brain, behavior, and immunity 57, 10-20, 2016 | 335 | 2016 |
AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3 A Denes, G Coutts, N Lénárt, SM Cruickshank, P Pelegrin, J Skinner, ... Proceedings of the National Academy of Sciences 112 (13), 4050-4055, 2015 | 263 | 2015 |
Inflammasomes link vascular disease with neuroinflammation and brain disorders N Lénárt, D Brough, Á Dénes Journal of Cerebral Blood Flow & Metabolism 36 (10), 1668-1685, 2016 | 161 | 2016 |
Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms R Fekete, C Cserép, N Lénárt, K Tóth, B Orsolits, B Martinecz, E Méhes, ... Acta neuropathologica 136, 461-482, 2018 | 136 | 2018 |
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions E Császár, N Lénárt, C Cserép, Z Környei, R Fekete, B Pósfai, D Balázsfi, ... Journal of Experimental Medicine 219 (3), 2022 | 111 | 2022 |
Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice ME Tóth, V Szegedi, E Varga, G Juhász, J Horváth, E Borbély, B Csibrány, ... Cell Stress and Chaperones 18 (6), 759-771, 2013 | 110 | 2013 |
Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1–induced mechanisms Z Helyes, V Tékus, N Szentes, K Pohóczky, B Botz, T Kiss, Á Kemény, ... Proceedings of the National Academy of Sciences 116 (26), 13067-13076, 2019 | 85 | 2019 |
Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer KL Singel, KS Grzankowski, ANMNH Khan, MJ Grimm, AC D’Auria, ... British journal of cancer 120 (2), 207-217, 2019 | 73 | 2019 |
Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons R Wong, N Lénárt, L Hill, L Toms, G Coutts, B Martinecz, E Császár, ... Brain, behavior, and immunity 76, 126-138, 2019 | 65 | 2019 |
A novel SPECT-based approach reveals early mechanisms of central and peripheral inflammation after cerebral ischemia K Szigeti, I Horváth, DS Veres, B Martinecz, N Lénárt, N Kovács, E Bakcsa, ... Journal of Cerebral Blood Flow & Metabolism 35 (12), 1921-1929, 2015 | 36 | 2015 |
Mannose-binding lectin drives platelet inflammatory phenotype and vascular damage after cerebral ischemia in mice via IL (Interleukin)-1α F Orsini, S Fumagalli, E Császár, K Tóth, D De Blasio, R Zangari, N Lénárt, ... Arteriosclerosis, Thrombosis, and Vascular Biology 38 (11), 2678-2690, 2018 | 35 | 2018 |
Hypoglycemia-activated hypothalamic microglia impairs glucose counterregulatory responses Z Winkler, D Kuti, Á Polyák, B Juhász, K Gulyás, N Lénárt, Á Dénes, ... Scientific reports 9 (1), 6224, 2019 | 33 | 2019 |
Cultured cells of the blood–brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment N Lénárt, FR Walter, A Bocsik, P Sántha, ME Tóth, A Harazin, AE Tóth, ... Fluids and Barriers of the CNS 12, 1-16, 2015 | 33 | 2015 |
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies S Heindl, A Ricci, O Carofiglio, Q Zhou, T Arzberger, N Lenart, ... Journal of Experimental Medicine 218 (8), e20202411, 2021 | 31 | 2021 |
Microglia alter the threshold of spreading depolarization and related potassium uptake in the mouse brain DP Varga, Á Menyhárt, B Pósfai, E Császár, N Lénárt, C Cserép, ... Journal of Cerebral Blood Flow & Metabolism 40 (1_suppl), S67-S80, 2020 | 30 | 2020 |
Low dosage of rimonabant leads to anxiolytic-like behavior via inhibiting expression levels and G-protein activity of kappa opioid receptors in a cannabinoid receptor … F Zádor, N Lénárt, B Csibrány, M Sántha, M Molnár, B Tuka, R Samavati, ... Neuropharmacology 89, 298-307, 2015 | 26 | 2015 |
Increased tau phosphorylation and impaired presynaptic function in hypertriglyceridemic ApoB-100 transgenic mice N Lénárt, V Szegedi, G Juhász, A Kasztner, J Horváth, E Bereczki, ... Public Library of Science 7 (9), e46007, 2012 | 25 | 2012 |
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner K Tóth, N Lénárt, P Berki, R Fekete, E Szabadits, B Pósfai, C Cserép, ... PLoS biology 20 (1), e3001526, 2022 | 23 | 2022 |