| A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity M Jinek, K Chylinski, I Fonfara, M Hauer, JA Doudna, E Charpentier science 337 (6096), 816-821, 2012 | 10728 | 2012 |
| RNA-programmed genome editing in human cells M Jinek, A East, A Cheng, S Lin, E Ma, J Doudna elife 2, e00471, 2013 | 1962 | 2013 |
| DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 SH Sternberg, S Redding, M Jinek, EC Greene, JA Doudna Nature 507 (7490), 62-67, 2014 | 1420 | 2014 |
| Structures of Cas9 endonucleases reveal RNA-mediated conformational activation M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ... Science 343 (6176), 2014 | 932 | 2014 |
| Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease C Anders, O Niewoehner, A Duerst, M Jinek Nature 513 (7519), 569-573, 2014 | 930 | 2014 |
| A three-dimensional view of the molecular machinery of RNA interference M Jinek, JA Doudna nature 457 (7228), 405-412, 2009 | 849 | 2009 |
| Method and apparatus for awarding and redeeming promotional points at an electronic game WR Adams, TJ Matthews US Patent 7,025,674, 2006 | 762 | 2006 |
| Sequence-and structure-specific RNA processing by a CRISPR endonuclease RE Haurwitz, M Jinek, B Wiedenheft, K Zhou, JA Doudna Science 329 (5997), 1355-1358, 2010 | 745 | 2010 |
| A prudent path forward for genomic engineering and germline gene modification D Baltimore, P Berg, M Botchan, D Carroll, RA Charo, G Church, JE Corn, ... Science 348 (6230), 36-38, 2015 | 716 | 2015 |
| Structural biology of nucleocytoplasmic transport A Cook, F Bono, M Jinek, E Conti Annu. Rev. Biochem. 76, 647-671, 2007 | 539 | 2007 |
| Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation MR Fabian, G Mathonnet, T Sundermeier, H Mathys, JT Zipprich, ... Molecular cell 35 (6), 868-880, 2009 | 456 | 2009 |
| Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription JA Doudna, M Jinek, E Charpentier, K Chylinski US Patent 10,266,850, 2019 | 417 | 2019 |
| The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin α M Jínek, J Rehwinkel, BD Lazarus, E Izaurralde, JA Hanover, E Conti Nature structural & molecular biology 11 (10), 1001-1007, 2004 | 306 | 2004 |
| Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense B Wiedenheft, K Zhou, M Jinek, SM Coyle, W Ma, JA Doudna Structure 17 (6), 904-912, 2009 | 272 | 2009 |
| An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3 DG Sashital, M Jinek, JA Doudna Nature structural & molecular biology 18 (6), 680, 2011 | 265 | 2011 |
| Structural insights into the molecular mechanism of the m6A writer complex P Śledź, M Jinek elife 5, e18434, 2016 | 204 | 2016 |
| Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription JA Doudna, M Jinek, K Chylinski, E Charpentier US Patent 10,113,167, 2018 | 190* | 2018 |
| Structural basis for guide RNA processing and seed-dependent DNA targeting by CRISPR-Cas12a DC Swarts, J van der Oost, M Jinek Molecular cell 66 (2), 221-233. e4, 2017 | 183 | 2017 |
| Methods and devices for reentering a true lumen from a subintimal space J Simpson, M Rosenthal, G Venegas, D Doud, J Ashley US Patent App. 10/421,980, 2004 | 182 | 2004 |
| Endoribonuclease compositions and methods of use thereof RE Haurwitz, JA Doudna, B Wiedenheft, M Jinek US Patent 9,115,348, 2015 | 179 | 2015 |
