Follow
Christopher Boehm
Christopher Boehm
Verified email at utoronto.ca
Title
Cited by
Cited by
Year
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
E Rogaeva, Y Meng, JH Lee, Y Gu, T Kawarai, F Zou, T Katayama, ...
Nature genetics 39 (2), 168-177, 2007
14032007
TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity
F Chen, H Hasegawa, G Schmitt-Ulms, T Kawarai, C Bohm, T Katayama, ...
Nature 440 (7088), 1208-1212, 2006
4002006
Coding mutations in SORL1 and Alzheimer disease
BN Vardarajan, Y Zhang, JH Lee, R Cheng, C Bohm, M Ghani, C Reitz, ...
Annals of neurology 77 (2), 215-227, 2015
1882015
Coding mutations in SORL1 and Alzheimer disease
BN Vardarajan, Y Zhang, JH Lee, R Cheng, C Bohm, M Ghani, C Reitz, ...
Annals of neurology 77 (2), 215-227, 2015
1882015
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, SP Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, ...
Human molecular genetics 21 (1), 1-9, 2012
1242012
SorLA signaling by regulated intramembrane proteolysis
C Böhm, NM Seibel, B Henkel, H Steiner, C Haass, W Hampe
Journal of Biological Chemistry 281 (21), 14547-14553, 2006
882006
Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways
C Bohm, F Chen, J Sevalle, S Qamar, R Dodd, Y Li, G Schmitt-Ulms, ...
Molecular and cellular neuroscience 66, 3-11, 2015
792015
SORL1 mutations in early- and late-onset Alzheimer disease
ML Cuccaro, RM Carney, Y Zhang, C Bohm, BW Kunkle, BN Vardarajan, ...
Neurology: Genetics 2 (6), e116, 2016
742016
Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes
Y Li, SHJ Lu, CJ Tsai, C Bohm, S Qamar, RB Dodd, W Meadows, A Jeon, ...
Structure 22 (1), 125-135, 2014
702014
APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes
R Pardossi-Piquard, SP Yang, S Kanemoto, Y Gu, F Chen, C Böhm, ...
Journal of biological chemistry 284 (24), 16298-16307, 2009
502009
Hu‐K4 is a ubiquitously expressed type 2 transmembrane protein associated with the endoplasmic reticulum
A Munck, C Böhm, NM Seibel, Z Hashemol Hosseini, W Hampe
The FEBS journal 272 (7), 1718-1726, 2005
492005
Structural biology of presenilin 1 complexes
Y Li, C Bohm, R Dodd, F Chen, S Qamar, G Schmitt-Ulms, PE Fraser, ...
Molecular neurodegeneration 9, 1-10, 2014
452014
TMP21 transmembrane domain regulates γ-secretase cleavage
R Pardossi-Piquard, C Böhm, F Chen, S Kanemoto, F Checler, ...
Journal of biological chemistry 284 (42), 28634-28641, 2009
432009
Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90
CB Knobbe, TJ Revett, Y Bai, V Chow, AHW Jeon, C Böhm, S Ehsani, ...
Journal of proteome research 10 (10), 4388-4404, 2011
312011
Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway
Y Zhang, Y Zhang, Y Aman, CT Ng, WH Chau, Z Zhang, M Yue, C Bohm, ...
Brain 144 (9), 2759-2770, 2021
242021
Interactome analyses of mature γ-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2
AHW Jeon, C Böhm, F Chen, H Huo, X Ruan, CH Ren, K Ho, S Qamar, ...
Journal of Biological Chemistry 288 (21), 15352-15366, 2013
192013
Vigilin interacts with signal peptide peptidase
SHJ Lu, AHW Jeon, G Schmitt-Ulms, S Qamar, R Dodd, B McDonald, Y Li, ...
Proteome science 10, 1-13, 2012
122012
SORL1 mutations in early-and late-onset Alzheimer disease. Neurol Genet 2: e116
ML Cuccaro, RM Carney, Y Zhang, C Bohm, BW Kunkle, BN Vardarajan, ...
42016
ALS mutations in FUS causes neuronal dysfunction and death in C. elegans by a dominant gainof-function mechanism
T Murakami, SP Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, ...
Hum Mol Genet, 2011
32011
P4‐049: Picalm but not bin1 alters the secretion of beta‐amyloid peptide
C Boehm, D Kaden, P St. George‐Hyslop
Alzheimer's & Dementia 8 (4S_Part_18), P652-P652, 2012
22012
The system can't perform the operation now. Try again later.
Articles 1–20