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Hiroshi Akazawa
Hiroshi Akazawa
Adresse e-mail validée de umin.ac.jp
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p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
M Sano, T Minamino, H Toko, H Miyauchi, M Orimo, Y Qin, H Akazawa, ...
Nature 446 (7134), 444-448, 2007
10092007
Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes
K Matsuura, T Nagai, N Nishigaki, T Oyama, J Nishi, H Wada, M Sano, ...
Journal of Biological Chemistry 279 (12), 11384-11391, 2004
8572004
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
Y Zou, H Akazawa, Y Qin, M Sano, H Takano, T Minamino, N Makita, ...
Nature cell biology 6 (6), 499-506, 2004
7762004
G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes
M Harada, Y Qin, H Takano, T Minamino, Y Zou, H Toko, M Ohtsuka, ...
Nature medicine 11 (3), 305-311, 2005
7442005
Developmental stage-specific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis
AT Naito, I Shiojima, H Akazawa, K Hidaka, T Morisaki, A Kikuchi, ...
Proceedings of the National Academy of Sciences 103 (52), 19812-19817, 2006
6232006
Roles of cardiac transcription factors in cardiac hypertrophy
H Akazawa, I Komuro
Circulation research 92 (10), 1079-1088, 2003
5212003
Angiogenesis and cardiac hypertrophy: maintenance of cardiac function and causative roles in heart failure
T Oka, H Akazawa, AT Naito, I Komuro
Circulation research 114 (3), 565-571, 2014
4462014
Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo
T Oyama, T Nagai, H Wada, AT Naito, K Matsuura, K Iwanaga, ...
The Journal of cell biology 176 (3), 329-341, 2007
4082007
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes
AT Naito, T Sumida, S Nomura, ML Liu, T Higo, A Nakagawa, K Okada, ...
Cell 149 (6), 1298-1313, 2012
3212012
Cardiac transcription factor Csx/Nkx2-5: Its role in cardiac development and diseases
H Akazawa, I Komuro
Pharmacology & therapeutics 107 (2), 252-268, 2005
3162005
Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization
M Ohtsuka, H Takano, Y Zou, H Toko, H Akazawa, Y Qin, M Suzuki, ...
The FASEB journal 18 (7), 851-853, 2004
2782004
Integrins play a critical role in mechanical stress–induced p38 MAPK activation
R Aikawa, T Nagai, S Kudoh, Y Zou, M Tanaka, M Tamura, H Akazawa, ...
Hypertension 39 (2), 233-238, 2002
2702002
Oxidative stress-induced signal transduction pathways in cardiac myocytes: involvement of ROS in heart diseases
H Takano, Y Zou, H Hasegawa, H Akazawa, T Nagai, I Komuro
Antioxidants and Redox Signaling 5 (6), 789-794, 2003
2552003
Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization
K Tateno, T Minamino, H Toko, H Akazawa, N Shimizu, S Takeda, ...
Circulation research 98 (9), 1194-1202, 2006
2472006
Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents
I Shimizu, T Minamino, H Toko, S Okada, H Ikeda, N Yasuda, K Tateno, ...
The Journal of clinical investigation 120 (5), 1506-1514, 2010
2462010
Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure
T Kamo, H Akazawa, W Suda, A Saga-Kamo, Y Shimizu, H Yagi, Q Liu, ...
PloS one 12 (3), e0174099, 2017
2442017
Cardiac mast cells cause atrial fibrillation through PDGF-A–mediated fibrosis in pressure-overloaded mouse hearts
C Liao, H Akazawa, M Tamagawa, K Ito, N Yasuda, Y Kudo, R Yamamoto, ...
The Journal of clinical investigation 120 (1), 242-253, 2010
2272010
Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease
S Koyama, K Ito, C Terao, M Akiyama, M Horikoshi, Y Momozawa, ...
Nature genetics 52 (11), 1169-1177, 2020
2202020
Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure
S Nomura, M Satoh, T Fujita, T Higo, T Sumida, T Ko, T Yamaguchi, ...
Nature communications 9 (1), 4435, 2018
2122018
Conformational switch of angiotensin II type 1 receptor underlying mechanical stress‐induced activation
N Yasuda, S Miura, H Akazawa, T Tanaka, Y Qin, Y Kiya, S Imaizumi, ...
EMBO reports 9 (2), 179-186, 2008
2122008
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