Weili Zheng
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The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism
L Jin, X Feng, H Rong, Z Pan, Y Inaba, L Qiu, W Zheng, S Lin, R Wang, ...
Nature communications 4 (1), 1-8, 2013
Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency
W Zheng, L Qiu, R Wang, X Feng, Y Han, Y Zhu, D Chen, Y Liu, L Jin, Y Li
Scientific reports 5, 12222, 2015
Structure of the calcium-dependent type 2 secretion pseudopilus
A Lopez-Castilla, JL Thomassin, B Bardiaux, W Zheng, M Nivaskumar, ...
Nature microbiology 2 (12), 1686-1695, 2017
Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease
L Jin, R Wang, Y Zhu, W Zheng, Y Han, F Guo, FB Ye, Y Li
Scientific reports 5, 17288, 2015
Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions
CN Spaulding, HL Schreiber IV, W Zheng, KW Dodson, JE Hazen, ...
Elife 7, e31662, 2018
Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose …
W Zheng, X Feng, L Qiu, Z Pan, R Wang, S Lin, D Hou, L Jin, Y Li
Diabetologia 56 (2), 401-411, 2013
Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells
S Wang, Z Wang, S Lin, W Zheng, R Wang, S Jin, J Chen, L Jin, Y Li
Biochemical Journal 446 (1), 79-87, 2012
Refined Cryo-EM structure of the T4 tail tube: exploring the lowest dose limit
W Zheng, F Wang, NMI Taylor, RC Guerrero-Ferreira, PG Leiman, ...
Structure 25 (9), 1436-1441. e2, 2017
Cryo-EM structure of the NLRC4CARD filament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly
M Matyszewski, W Zheng, J Lueck, B Antiochos, EH Egelman, J Sohn
Journal of Biological Chemistry 293 (52), 20240-20248, 2018
Identification of an oleanane-type triterpene hedragonic acid as a novel farnesoid X receptor ligand with liver protective effects and anti-inflammatory activity
Y Lu, W Zheng, S Lin, F Guo, Y Zhu, Y Wei, X Liu, S Jin, L Jin, Y Li
Molecular pharmacology 93 (2), 63-72, 2018
The AAA+ ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn
FE Demircioglu, W Zheng, AJ McQuown, NK Maier, N Watson, ...
Nature communications 10 (1), 1-12, 2019
Structure and assembly of the enterohemorrhagic Escherichia coli type 4 pilus
B Bardiaux, GC de Amorim, AL Rico, W Zheng, I Guilvout, C Jollivet, ...
Structure 27 (7), 1082-1093. e5, 2019
Structural insights into the heterodimeric complex of the nuclear receptors FXR and RXR
W Zheng, Y Lu, S Tian, F Ma, Y Wei, S Xu, Y Li
Journal of Biological Chemistry 293 (32), 12535-12541, 2018
Functional reconstitution of the type IVa pilus assembly system from enterohaemorrhagic Escherichia coli
A Luna Rico, W Zheng, N Petiot, EH Egelman, O Francetic
Molecular microbiology 111 (3), 732-749, 2019
A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co‐regulator Assembly
W Zheng, Y Lu, S Lin, R Wang, L Qiu, Y Zhu, B Yao, F Guo, S Jin, L Jin, ...
ChemBioChem 18 (8), 721-725, 2017
Structural insights into the nuclear import of the histone acetyltransferase males‐absent‐on‐the‐first by importin α1
W Zheng, R Wang, X Liu, S Tian, B Yao, A Chen, S Jin, Y Li
Traffic 19 (1), 19-28, 2018
Structural basis for the hepatoprotective effects of antihypertensive 1, 4-dihydropyridine drugs
Y Wei, Y Lu, Y Zhu, W Zheng, F Guo, B Yao, S Xu, Y Wang, L Jin, Y Li
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (10), 2261-2270, 2018
Cryo-EM structure of the CFA/I pilus rod
W Zheng, M Andersson, N Mortezaei, E Bullitt, E Egelman
IUCrJ 6 (5), 2019
Osteogenesis imperfecta mutations in plastin 3 lead to impaired calcium regulation of actin bundling
CL Schwebach, E Kudryashova, W Zheng, M Orchard, H Smith, ...
Bone Research 8 (1), 1-13, 2020
Revealing a mutant-induced receptor allosteric mechanism for the thyroid hormone resistance
B Yao, Y Wei, S Zhang, S Tian, S Xu, R Wang, W Zheng, Y Li
Iscience 20, 489-496, 2019
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