| The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism L Jin, X Feng, H Rong, Z Pan, Y Inaba, L Qiu, W Zheng, S Lin, R Wang, ... Nature communications 4 (1), 1937, 2013 | 150 | 2013 |
| Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions CN Spaulding, HL Schreiber IV, W Zheng, KW Dodson, JE Hazen, ... Elife 7, e31662, 2018 | 71 | 2018 |
| Structure of the calcium-dependent type 2 secretion pseudopilus A Lopez-Castilla, JL Thomassin, B Bardiaux, W Zheng, M Nivaskumar, ... Nature microbiology 2 (12), 1686-1695, 2017 | 68 | 2017 |
| Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency W Zheng, L Qiu, R Wang, X Feng, Y Han, Y Zhu, D Chen, Y Liu, L Jin, Y Li Scientific reports 5 (1), 12222, 2015 | 61 | 2015 |
| Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease L Jin, R Wang, Y Zhu, W Zheng, Y Han, F Guo, FB Ye, Y Li Scientific reports 5 (1), 17288, 2015 | 45 | 2015 |
| Refined cryo-EM structure of the T4 tail tube: exploring the lowest dose limit W Zheng, F Wang, NMI Taylor, RC Guerrero-Ferreira, PG Leiman, ... Structure 25 (9), 1436-1441. e2, 2017 | 43 | 2017 |
| Structural insights into the heterodimeric complex of the nuclear receptors FXR and RXR W Zheng, Y Lu, S Tian, F Ma, Y Wei, S Xu, Y Li Journal of Biological Chemistry 293 (32), 12535-12541, 2018 | 40 | 2018 |
| Structure and assembly of the enterohemorrhagic Escherichia coli type 4 pilus B Bardiaux, GC de Amorim, AL Rico, W Zheng, I Guilvout, C Jollivet, ... Structure 27 (7), 1082-1093. e5, 2019 | 38 | 2019 |
| Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments F Wang, DP Baquero, LC Beltran, Z Su, T Osinski, W Zheng, ... Proceedings of the National Academy of Sciences 117 (33), 19643-19652, 2020 | 34 | 2020 |
| Osteogenesis imperfecta mutations in plastin 3 lead to impaired calcium regulation of actin bundling CL Schwebach, E Kudryashova, W Zheng, M Orchard, H Smith, ... Bone research 8 (1), 21, 2020 | 34 | 2020 |
| Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose … W Zheng, X Feng, L Qiu, Z Pan, R Wang, S Lin, D Hou, L Jin, Y Li Diabetologia 56, 401-411, 2013 | 32 | 2013 |
| Identification of an oleanane-type triterpene hedragonic acid as a novel farnesoid X receptor ligand with liver protective effects and anti-inflammatory activity Y Lu, W Zheng, S Lin, F Guo, Y Zhu, Y Wei, X Liu, S Jin, L Jin, Y Li Molecular pharmacology 93 (2), 63-72, 2018 | 31 | 2018 |
| Cryo-EM structure of the NLRC4CARD filament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly M Matyszewski, W Zheng, J Lueck, B Antiochos, EH Egelman, J Sohn Journal of Biological Chemistry 293 (52), 20240-20248, 2018 | 30 | 2018 |
| Cryoelectron-microscopic structure of the pKpQIL conjugative pili from carbapenem-resistant Klebsiella pneumoniae W Zheng, A Pena, WW Low, JLC Wong, G Frankel, EH Egelman Structure 28 (12), 1321-1328. e2, 2020 | 27 | 2020 |
| The AAA+ ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn FE Demircioglu, W Zheng, AJ McQuown, NK Maier, N Watson, ... Nature Communications 10 (1), 3262, 2019 | 24 | 2019 |
| Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells S Wang, Z Wang, S Lin, W Zheng, R Wang, S Jin, J Chen, L Jin, Y Li Biochemical Journal 446 (1), 79-87, 2012 | 24 | 2012 |
| Convergent evolution in the supercoiling of prokaryotic flagellar filaments MAB Kreutzberger, RR Sonani, J Liu, S Chatterjee, F Wang, AL Sebastian, ... Cell 185 (19), 3487-3500. e14, 2022 | 18 | 2022 |
| Revealing a mutant-induced receptor allosteric mechanism for the thyroid hormone resistance B Yao, Y Wei, S Zhang, S Tian, S Xu, R Wang, W Zheng, Y Li Iscience 20, 489-496, 2019 | 18 | 2019 |
| Functional reconstitution of the type IVa pilus assembly system from enterohaemorrhagic Escherichia coli A Luna Rico, W Zheng, N Petiot, EH Egelman, O Francetic Molecular microbiology 111 (3), 732-749, 2019 | 18 | 2019 |
| Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome M Matyszewski, W Zheng, J Lueck, Z Mazanek, N Mohideen, AY Lau, ... Nature communications 12 (1), 2735, 2021 | 15 | 2021 |
