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Nicolas Bolik-Coulon
Nicolas Bolik-Coulon
department of molecular genetics, the University of Toronto, Toronto, Canada
Adresse e-mail validée de utoronto.ca
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Structure and dynamics of an intrinsically disordered protein region that partially folds upon binding by chemical-exchange NMR
C Charlier, G Bouvignies, P Pelupessy, A Walrant, R Marquant, M Kozlov, ...
Journal of the American Chemical Society 139 (35), 12219-12227, 2017
462017
Time-resolved protein side-chain motions unraveled by high-resolution relaxometry and molecular dynamics simulations
SF Cousin, P Kadeřávek, N Bolik-Coulon, Y Gu, C Charlier, L Carlier, ...
Journal of the American Chemical Society 140 (41), 13456-13465, 2018
412018
Theoretical and computational framework for the analysis of the relaxation properties of arbitrary spin systems. Application to high-resolution relaxometry
N Bolik-Coulon, P Kadeřávek, P Pelupessy, JN Dumez, F Ferrage, ...
Journal of Magnetic Resonance 313, 106718, 2020
182020
Caspase-6 undergoes a distinct helix-strand interconversion upon substrate binding
KB Dagbay, N Bolik-Coulon, SN Savinov, JA Hardy
Journal of Biological Chemistry 292 (12), 4885-4897, 2017
162017
Protein dynamics from accurate low-field site-specific longitudinal and transverse nuclear spin relaxation
P Kadeřávek, N Bolik-Coulon, SF Cousin, T Marquardsen, JM Tyburn, ...
The Journal of Physical Chemistry Letters 10 (19), 5917-5922, 2019
132019
How wide is the window opened by high-resolution relaxometry on the internal dynamics of proteins in solution?
AA Smith, N Bolik-Coulon, M Ernst, BH Meier, F Ferrage
Journal of Biomolecular NMR 75, 119-131, 2021
122021
Correlating histone acetylation with nucleosome core particle dynamics and function
TH Kim, ML Nosella, N Bolik-Coulon, RW Harkness, SK Huang, LE Kay
Proceedings of the National Academy of Sciences 120 (15), e2301063120, 2023
112023
Determination of protein ps-ns motions by high-resolution relaxometry
SF Cousin, P Kadeřávek, N Bolik-Coulon, F Ferrage
Protein NMR: Methods and Protocols, 169-203, 2018
102018
Boosting the resolution of low-field relaxation experiments on intrinsically disordered proteins with triple-resonance NMR
Z Jaseňáková, V Zapletal, P Padrta, M Zachrdla, N Bolik-Coulon, ...
Journal of biomolecular NMR 74 (2), 139-145, 2020
92020
Less is more: A simple methyl-TROSY based pulse scheme offers improved sensitivity in applications to high molecular weight complexes
N Bolik-Coulon, AIM Sever, RW Harkness, JM Aramini, Y Toyama, ...
Journal of Magnetic Resonance 346, 107326, 2023
82023
Understanding the methyl-TROSY effect over a wide range of magnetic fields
N Bolik-Coulon, SF Cousin, P Kadeřávek, JN Dumez, F Ferrage
The Journal of Chemical Physics 150 (22), 2019
82019
Intrinsically disordered proteins
N Bolik-Coulon, G Bouvignies, L Carlier, F Ferrage
Elsevier, 2019
82019
Explicit models of motions to analyze NMR relaxation data in proteins
N Bolik-Coulon, F Ferrage
The Journal of Chemical Physics 157 (12), 2022
62022
The structure of SDS22 provides insights into the mechanism of heterodimer formation with PP1
MS Choy, N Bolik-Coulon, TL Archuleta, W Peti, R Page
Acta Crystallographica Section F: Structural Biology Communications 74 (12 …, 2018
62018
Optimizing frequency sampling in CEST experiments
N Bolik-Coulon, DF Hansen, LE Kay
Journal of Biomolecular NMR 76 (5), 167-183, 2022
52022
Explicit models of motion to understand protein side-chain dynamics
N Bolik-Coulon, O Languin-Cattoën, D Carnevale, M Zachrdla, D Laage, ...
Physical Review Letters 129 (20), 203001, 2022
52022
Experimental characterization of the dynamics of IDPs and IDRs by NMR
N Bolik-Coulon, G Bouvignies, L Carlier, F Ferrage
Intrinsically Disordered Proteins, 65-92, 2019
42019
Inhibitor-3 inhibits Protein Phosphatase 1 via a metal binding dynamic protein–protein interaction
G Srivastava, MS Choy, N Bolik-Coulon, R Page, W Peti
Nature Communications 14 (1), 1798, 2023
32023
Unraveling motion in proteins by combining NMR relaxometry and molecular dynamics simulations: A case study on ubiquitin
C Champion, M Lehner, AA Smith, F Ferrage, N Bolik-Coulon, S Riniker
The Journal of Chemical Physics 160 (10), 2024
12024
Comprehensive analysis of relaxation decays from high-resolution relaxometry
N Bolik-Coulon, M Zachrdla, G Bouvignies, P Pelupessy, F Ferrage
Journal of Magnetic Resonance 355, 107555, 2023
12023
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