Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas H Kutay, S Bai, J Datta, T Motiwala, I Pogribny, W Frankel, ST Jacob, ... Journal of cellular biochemistry 99 (3), 671-678, 2006 | 796 | 2006 |
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear … K Ghoshal, J Datta, S Majumder, S Bai, H Kutay, T Motiwala, ST Jacob Molecular and cellular biology, 2005 | 531 | 2005 |
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression K Ghoshal, S Majumder, J Datta, T Motiwala, S Bai, SM Sharma, ... Journal of Biological Chemistry 279 (8), 6783-6793, 2004 | 228 | 2004 |
Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation L Alinari, KV Mahasenan, F Yan, V Karkhanis, JH Chung, EM Smith, ... Blood, The Journal of the American Society of Hematology 125 (16), 2530-2543, 2015 | 162 | 2015 |
Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein α by … J Datta, S Majumder, H Kutay, T Motiwala, W Frankel, R Costa, HC Cha, ... Cancer research 67 (6), 2736-2746, 2007 | 147 | 2007 |
Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas T Motiwala, K Ghoshal, A Das, S Majumder, D Weichenhan, YZ Wu, ... Oncogene 22 (41), 6319-6331, 2003 | 144 | 2003 |
HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors K Ghoshal, T Motiwala, R Claus, P Yan, H Kutay, J Datta, S Majumder, ... PloS one 5 (4), e10338, 2010 | 87 | 2010 |
Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia T Motiwala, S Majumder, H Kutay, DS Smith, DS Neuberg, DM Lucas, ... Clinical cancer research 13 (11), 3174-3181, 2007 | 79 | 2007 |
The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer JM Barajas, R Reyes, MJ Guerrero, ST Jacob, T Motiwala, K Ghoshal Scientific Reports 8 (1), 9105, 2018 | 72 | 2018 |
Epigenetic regulation of protein tyrosine phosphatases: potential molecular targets for cancer therapy ST Jacob, T Motiwala Cancer gene therapy 12 (8), 665-672, 2005 | 67 | 2005 |
Role of protein tyrosine phosphatases in cancer T Motiwala, ST Jacob Progress in nucleic acid research and molecular biology 81, 297-329, 2006 | 59 | 2006 |
Sorafenib and 2-deoxyglucose synergistically inhibit proliferation of both sorafenib-sensitive and-resistant HCC cells by inhibiting ATP production R Reyes, NA Wani, K Ghoshal, ST Jacob, T Motiwala Gene expression 17 (2), 129, 2017 | 57 | 2017 |
Reprogramming of glucose metabolism by zerumbone suppresses hepatocarcinogenesis NA Wani, B Zhang, K Teng, JM Barajas, T Motiwala, P Hu, L Yu, ... Molecular Cancer Research 16 (2), 256-268, 2018 | 37 | 2018 |
CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128 M Badawi, J Kim, A Dauki, D Sutaria, T Motiwala, R Reyes, N Wani, ... Oncotarget 9 (40), 26032, 2018 | 34 | 2018 |
Lyn kinase and ZAP70 are substrates of PTPROt in B‐cells: Lyn inactivation by PTPROt sensitizes leukemia cells to VEGF‐R inhibitor pazopanib T Motiwala, J Datta, H Kutay, S Roy, ST Jacob Journal of cellular biochemistry 110 (4), 846-856, 2010 | 32 | 2010 |
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma K Regan-Fendt, D Li, R Reyes, L Yu, NA Wani, P Hu, ST Jacob, ... Cancers 12 (10), 2730, 2020 | 28 | 2020 |
Regulation of glucose metabolism in hepatocarcinogenesis by microRNAs RK Reyes, T Motiwala, ST Jacob Gene expression 16 (2), 85, 2014 | 27 | 2014 |
Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate S Hsu, T Motiwala, S Roy, R Claus, M Mustafa, C Plass, MA Freitas, ... Journal of cellular biochemistry 114 (8), 1810-1818, 2013 | 26 | 2013 |
Reduced Susceptibility of DNA Methyltransferase 1 Hypomorphic (Dnmt1N/+) Mice to Hepatic Steatosis upon Feeding Liquid Alcohol Diet H Kutay, C Klepper, B Wang, S Hsu, J Datta, L Yu, X Zhang, S Majumder, ... Public Library of Science 7 (8), e41949, 2012 | 26 | 2012 |
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia T Motiwala, N Zanesi, J Datta, S Roy, H Kutay, AM Checovich, M Kaou, ... Blood, The Journal of the American Society of Hematology 118 (23), 6132-6140, 2011 | 24 | 2011 |