| The SsrA–SmpB system for protein tagging, directed degradation and ribosome rescue AW Karzai, ED Roche, RT Sauer Nature structural biology 7 (6), 449-455, 2000 | 538 | 2000 |
| SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA) AW Karzai, MM Susskind, RT Sauer The EMBO journal 18 (13), 3793-3799, 1999 | 408 | 1999 |
| A Bipartite Signaling Mechanism Involved in DnaJ-mediated Activation of the Escherichia coli DnaK Protein (∗) AW Karzai, R McMacken Journal of Biological Chemistry 271 (19), 11236-11246, 1996 | 307 | 1996 |
| The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A M Srinivasan, P Mehta, Y Yu, E Prugar, EV Koonin, AW Karzai, ... The EMBO journal 30 (5), 873-881, 2011 | 180 | 2011 |
| RNase R degrades non‐stop mRNAs selectively in an SmpB‐tmRNA‐dependent manner J Richards, P Mehta, AW Karzai Molecular microbiology 62 (6), 1700-1712, 2006 | 157 | 2006 |
| Protein factors associated with the SsrA⋅ SmpB tagging and ribosome rescue complex AW Karzai, RT Sauer Proceedings of the National Academy of Sciences 98 (6), 3040-3044, 2001 | 139 | 2001 |
| Trans-Translation: The tmRNA-Mediated Surveillance Mechanism for Ribosome Rescue, Directed Protein Degradation, and Nonstop mRNA Decay D Dulebohn, J Choy, T Sundermeier, N Okan, AW Karzai Biochemistry 46 (16), 4681-4693, 2007 | 135 | 2007 |
| DnaJ dramatically stimulates ATP hydrolysis by DnaK: insight into targeting of Hsp70 proteins to polypeptide substrates R Russell, AW Karzai, AF Mehl, R McMacken Biochemistry 38 (13), 4165-4176, 1999 | 135 | 1999 |
| Lon protease degrades transfer-messenger RNA-tagged proteins JS Choy, LL Aung, AW Karzai Journal of bacteriology 189 (18), 6564-6571, 2007 | 132 | 2007 |
| Simultaneous and functional binding of SmpB and EF-Tu· GTP to the alanyl acceptor arm of tmRNA S Barends, AW Karzai, RT Sauer, J Wower, B Kraal Journal of molecular biology 314 (1), 9-21, 2001 | 126 | 2001 |
| A role for the SmpB-SsrA system in Yersinia pseudotuberculosis pathogenesis NA Okan, JB Bliska, AW Karzai PLoS pathogens 2 (1), e6, 2006 | 118 | 2006 |
| A previously uncharacterized role for small protein B (SmpB) in transfer messenger RNA-mediated trans-translation TR Sundermeier, DP Dulebohn, HJ Cho, AW Karzai Proceedings of the National Academy of Sciences 102 (7), 2316-2321, 2005 | 99 | 2005 |
| The smpB-ssrA Mutant of Yersinia pestis Functions as a Live Attenuated Vaccine To Protect Mice against Pulmonary Plague Infection NA Okan, P Mena, JL Benach, JB Bliska, AW Karzai Infection and immunity 78 (3), 1284-1293, 2010 | 77 | 2010 |
| Origins of DNA-binding specificity: role of protein contacts with the DNA backbone JF Schildbach, AW Karzai, BE Raumann, RT Sauer Proceedings of the National Academy of Sciences 96 (3), 811-817, 1999 | 77 | 1999 |
| Quality control of bacterial mRNA decoding and decay J Richards, T Sundermeier, A Svetlanov, AW Karzai Biochimica Et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1779 (9), 574-582, 2008 | 68 | 2008 |
| Structural basis for distinct operational modes and protease activation in AAA+ protease Lon M Shin, C Puchades, A Asmita, N Puri, E Adjei, RL Wiseman, AW Karzai, ... Science advances 6 (21), eaba8404, 2020 | 56 | 2020 |
| Global Gene Expression Profiling of Yersinia pestis Replicating inside Macrophages Reveals the Roles of a Putative Stress-Induced Operon in Regulating Type III … HS Fukuto, A Svetlanov, LE Palmer, AW Karzai, JB Bliska Infection and immunity 78 (9), 3700-3715, 2010 | 55 | 2010 |
| tmRNA determinants required for facilitating nonstop mRNA decay P Mehta, J Richards, AW Karzai Rna 12 (12), 2187-2198, 2006 | 54 | 2006 |
| Francisella tularensis tmRNA system mutants are vulnerable to stress, avirulent in mice, and provide effective immune protection A Svetlanov, N Puri, P Mena, A Koller, AW Karzai Molecular microbiology 85 (1), 122-141, 2012 | 52 | 2012 |
| Non‐stop mRNA decay initiates at the ribosome Z Ge, P Mehta, J Richards, AW Karzai Molecular microbiology 78 (5), 1159-1170, 2010 | 52 | 2010 |
