Guillaume Gotthard
Guillaume Gotthard
Time Resolved Serial Crystallographer
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mScarlet: a bright monomeric red fluorescent protein for cellular imaging
DS Bindels, L Haarbosch, L Van Weeren, M Postma, KE Wiese, M Mastop, ...
Nature methods 14 (1), 53-56, 2017
Characterisation of the organophosphate hydrolase catalytic activity of SsoPox
J Hiblot, G Gotthard, E Chabriere, M Elias
Scientific reports 2 (1), 1-8, 2012
Structural and Enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus
J Hiblot, G Gotthard, E Chabriere, M Elias
Public Library of Science 7 (10), e47028, 2012
Differential active site loop conformations mediate promiscuous activities in the lactonase Sso Pox
J Hiblot, G Gotthard, M Elias, E Chabriere
PloS one 8 (9), e75272, 2013
Structural and enzymatic characterization of the phosphotriesterase OPHC2 from Pseudomonas pseudoalcaligenes
G Gotthard, J Hiblot, D Gonzalez, M Elias, E Chabriere
PloS one 8 (11), e77995, 2013
Mechanism and dynamics of fatty acid photodecarboxylase
D Sorigué, K Hadjidemetriou, S Blangy, G Gotthard, A Bonvalet, ...
Science 372 (6538), eabd5687, 2021
Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase
P Jacquet, J Hiblot, D Daudé, C Bergonzi, G Gotthard, N Armstrong, ...
Scientific reports 7 (1), 1-15, 2017
Tracking the route of molecular oxygen in O2-tolerant membrane-bound [NiFe] hydrogenase
J Kalms, A Schmidt, S Frielingsdorf, T Utesch, G Gotthard, D von Stetten, ...
Proceedings of the National Academy of Sciences 115 (10), E2229-E2237, 2018
Serial femtosecond crystallography and ultrafast absorption spectroscopy of the photoswitchable fluorescent protein IrisFP
JP Colletier, M Sliwa, FX Gallat, M Sugahara, V Guillon, G Schirò, ...
The Journal of Physical Chemistry Letters 7 (5), 882-887, 2016
Tailing miniSOG: structural bases of the complex photophysics of a flavin-binding singlet oxygen photosensitizing protein
J Torra, C Lafaye, L Signor, S Aumonier, C Flors, X Shu, S Nonell, ...
Scientific Reports 9 (1), 1-10, 2019
Structural analysis of the bright monomeric yellow-green fluorescent protein mNeonGreen obtained by directed evolution
D Clavel, G Gotthard, D Von Stetten, D De Sanctis, H Pasquier, ...
Acta Crystallographica Section D: Structural Biology 72 (12), 1298-1307, 2016
Specific radiation damage is a lesser concern at room temperature
G Gotthard, S Aumonier, D De Sanctis, G Leonard, D von Stetten, ...
IUCrJ 6 (4), 665-680, 2019
Kinetic and structural characterization of the self-labeling protein tags HaloTag7, SNAP-tag, and CLIP-tag
J Wilhelm, S Kühn, M Tarnawski, G Gotthard, J Tünnermann, ...
Biochemistry 60 (33), 2560-2575, 2021
Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy
GJ Gozzi, D Gonzalez, C Boudesco, AMM Dias, G Gotthard, B Uyanik, ...
Cell Death & Differentiation 27 (1), 117-129, 2020
Sac Pox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase
J Bzdrenga, J Hiblot, G Gotthard, C Champion, M Elias, E Chabriere
BMC research notes 7 (1), 1-9, 2014
Human-Phosphate-Binding-Protein inhibits HIV-1 gene transcription and replication
T Cherrier, M Elias, A Jeudy, G Gotthard, V Le Douce, H Hallay, P Masson, ...
Virology journal 8 (1), 1-7, 2011
Aequorea’s secrets revealed: New fluorescent proteins with unique properties for bioimaging and biosensing
GG Lambert, H Depernet, G Gotthard, DT Schultz, I Navizet, T Lambert, ...
PLoS biology 18 (11), e3000936, 2020
Crystallization and preliminary X-ray diffraction analysis of the organophosphorus hydrolase OPHC2 from Pseudomonas pseudoalcaligenes
G Gotthard, J Hiblot, D Gonzalez, E Chabriere, M Elias
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
The Drosophila odorant-binding protein 28a is involved in the detection of the floral odour ß-ionone
D Gonzalez, K Rihani, F Neiers, N Poirier, S Fraichard, G Gotthard, ...
Cellular and Molecular Life Sciences 77 (13), 2565-2577, 2020
Mechanistic investigations of green mEos4b reveal a dynamic long-lived dark state
E De Zitter, J Ridard, D Thédié, V Adam, B Levy, M Byrdin, G Gotthard, ...
Journal of the American Chemical Society 142 (25), 10978-10988, 2020
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