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Clara Pérez Peinado
Clara Pérez Peinado
Sr. Scientist - Biophysics and Process Analytics, Janssen Vaccines and Prevention B.V
Adresse e-mail validée de its.jnj.com
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Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn (15–34), antimicrobial peptides from rattlesnake venom
C Pérez-Peinado, SA Dias, MM Domingues, AH Benfield, JM Freire, ...
Journal of Biological Chemistry 293 (5), 1536-1549, 2018
982018
Structural dissection of crotalicidin, a rattlesnake venom cathelicidin, retrieves a fragment with antimicrobial and antitumor activity
CB Falcao, C Perez-Peinado, BG de la Torre, X Mayol, ...
Journal of medicinal chemistry 58 (21), 8553-8563, 2015
782015
Vipericidins: a novel family of cathelicidin-related peptides from the venom gland of South American pit vipers
CB Falcao, BG de La Torre, C Pérez-Peinado, AE Barron, D Andreu, ...
Amino acids 46, 2561-2571, 2014
782014
New potent membrane-targeting antibacterial peptides from viral capsid proteins
SA Dias, JM Freire, C Pérez-Peinado, MM Domingues, D Gaspar, N Vale, ...
Frontiers in Microbiology 8, 264008, 2017
452017
Hitchhiking with nature: snake venom peptides to fight cancer and superbugs
C Pérez-Peinado, S Defaus, D Andreu
Toxins 12 (4), 255, 2020
422020
To what extent do fluorophores bias the biological activity of peptides? A practical approach using membrane-active peptides as models
M Cavaco, C Pérez-Peinado, J Valle, RDM Silva, JDG Correia, D Andreu, ...
Frontiers in bioengineering and biotechnology 8, 552035, 2020
282020
Structural determinants conferring unusual long life in human serum to rattlesnake‐derived antimicrobial peptide Ctn [15‐34]
C Pérez‐Peinado, SA Dias, DA Mendonça, MARB Castanho, AS Veiga, ...
Journal of Peptide Science 25 (8), e3195, 2019
182019
Decoding the human serum interactome of snake-derived antimicrobial peptide Ctn [15-34]: Toward an explanation for unusually long half-life
C Pérez-Peinado, S Defaus, L Sans-Comerma, J Valle, D Andreu
Journal of proteomics 204, 103372, 2019
122019
Tumor Cell Attack by Crotalicidin (Ctn) and Its Fragment Ctn [15–34]: Insights into Their Dual Membranolytic and Intracellular Targeting Mechanism
C Pérez-Peinado, J Valle, JM Freire, D Andreu
ACS Chemical Biology 15 (11), 2945-2957, 2020
112020
Examining topoisomers of a snake-venom-derived peptide for improved antimicrobial and antitumoral properties
A Carrera-Aubesart, S Defaus, C Pérez-Peinado, D Sandín, M Torrent, ...
Biomedicines 10 (9), 2110, 2022
62022
Anti-HIV-1 Activity of pepRF1, a Proteolysis-Resistant CXCR4 Antagonist Derived from Dengue Virus Capsid Protein
I Cadima-Couto, A Tauzin, JM Freire, TN Figueira, RDM Silva, ...
ACS Infectious Diseases 7 (1), 6-22, 2020
52020
New potent membrane-targeting antibacterial peptides from viral capsid proteins. Front. Microbiol. 8, 1–9
SA Dias, JM Freire, C Pérez-Peinado, MM Domingues, D Gaspar, N Vale, ...
52017
The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis
M Cavaco, C Pérez-Peinado, J Valle, RDM Silva, L Gano, JDG Correia, ...
Biomedicine & Pharmacotherapy 174, 116573, 2024
2024
Anti-HIV-1 activity and mode of action of a viral-derived and proteolysis-resistant peptide targeting the chemokine receptor CXCR4
AS Veiga, I Cadima-Couto, A Tauzin, JM Freire, R Silva, C Perez-Peinado, ...
Biophysical Journal 123 (3), 166a, 2024
2024
Anti-HIV-1 activity and mode of action of a viral-derived and proteolysis-resistant peptide CXCR4 antagonist
I Cadima-Couto, A Tauzin, JM Freire, TN Figueira, RDM Silva, ...
FEBS OPEN BIO 11, 314-314, 2021
2021
Hitchhiking with Nature: exploring snake venom peptides to fight cancer and superbugs
C Pérez-Peinado
Universitat Pompeu Fabra, 2020
2020
Targeting brain metastases with a peptide conjugate
M Cavaco, C Perez-Peinado, D Gaspar, D Andreu, M Castanho, V Neves
FEBS OPEN BIO 9, 372-372, 2019
2019
Mechanisms of bacterial membrane permeabilization of snake venom-derived peptides crotalicidin (Ctn) and Ctn [15-34]
C Perez-Peinado, S Almeida Dias, MM Domingues, AH Benfield, ...
Journal of Peptide Science 24 (S2), S80-S80, 2018
2018
RATIONAL DISSECTION OF THE SNAKE-DERIVED PEPTIDE CROTALICIDIN RETRIEVES A FRAGMENT WITH ENHANCED ANTIMICROBIAL AND ANTITUMORAL PROPERTIES
C Perez-Peinado, CB Falcao, BG de la Torre, X Mayol, ...
JOURNAL OF PEPTIDE SCIENCE 22, S188-S188, 2016
2016
Supplementary Materials: Hitchhiking with Nature: Snake Venom Peptides to Fight Cancer and Superbugs
C Pérez-Peinado, S Defaus, D Andreu
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