Nec‐1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS 1 mice SH Yang, DK Lee, J Shin, S Lee, S Baek, J Kim, H Jung, JM Hah, YS Kim EMBO molecular medicine 9 (1), 61-77, 2017 | 139 | 2017 |
Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model J Shin, S Park, HY Lee, YS Kim Scientific reports 11 (1), 1617, 2021 | 30 | 2021 |
A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice SH Yang, J Shin, NN Shin, JH Hwang, SC Hong, K Park, JW Lee, S Lee, ... Scientific reports 9 (1), 4183, 2019 | 29 | 2019 |
Rhizolutin, a novel 7/10/6‐tricyclic dilactone, dissociates misfolded protein aggregates and reduces apoptosis/inflammation associated with Alzheimer's disease Y Kwon, J Shin, K Nam, JS An, SH Yang, SH Hong, M Bae, K Moon, ... Angewandte Chemie International Edition 59 (51), 22994-22998, 2020 | 20 | 2020 |
A Therapeutic Nanovaccine that Generates Anti‐Amyloid Antibodies and Amyloid‐specific Regulatory T Cells for Alzheimer's Disease M Jung, S Lee, S Park, J Hong, C Kim, I Cho, HS Sohn, K Kim, IW Park, ... Advanced Materials 35 (3), 2207719, 2023 | 19 | 2023 |
Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease DE Kwak, T Ko, HS Koh, YW Ji, J Shin, K Kim, HY Kim, HK Lee, YS Kim PLoS One 15 (1), e0227618, 2020 | 18 | 2020 |
Discovery of Chemicals to Either Clear or Indicate Amyloid Aggregates by Targeting Memory‐Impairing Anti‐Parallel Aβ Dimers JC Lee, HY Kim, S Lee, J Shin, HV Kim, K Kim, S Baek, D Lee, H Jeon, ... Angewandte Chemie International Edition 59 (28), 11491-11500, 2020 | 16 | 2020 |
Destruction of ERP responses to deviance in an auditory oddball paradigm in amyloid infusion mice with memory deficits B Kim, J Shin, YS Kim, JH Choi PLoS One 15 (3), e0230277, 2020 | 10 | 2020 |
Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer’s disease S Park, HY Kim, HA Oh, J Shin, IW Park, S Yoon, DH Woo, YS Kim Scientific reports 11 (1), 12043, 2021 | 9 | 2021 |
Azetidine-bearing non-ribosomal peptides, bonnevillamides D and E, isolated from a carrion beetle-associated actinomycete YH Shin, YH Ban, J Shin, IW Park, S Yoon, K Ko, J Shin, SJ Nam, ... The Journal of Organic Chemistry 86 (16), 11149-11159, 2021 | 9 | 2021 |
Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model DW Kim, JH Lee, HY Kim, J Shin, K Kim, S Lee, J Park, JI Kim, YS Kim PloS one 15 (12), e0243041, 2020 | 7 | 2020 |
Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse DW Kim, GH Bae, HY Kim, H Jeon, K Kim, J Shin, S Lee, S Hong, I Kim, ... ACS Chemical Neuroscience 12 (1), 99-108, 2020 | 7 | 2020 |
Amyloid against amyloid: Dimeric amyloid fragment ameliorates cognitive impairments by direct clearance of oligomers and plaques HY Lee, S Baek, M Cha, SH Yang, I Cho, H Shin, S Lee, HY Kim, S Lee, ... Angewandte Chemie 135 (7), e202210209, 2023 | 4 | 2023 |
Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models HY Lee, S Yoon, JH Lee, K Park, Y Jung, I Cho, D Lee, J Shin, K Kim, ... Alzheimer's Research & Therapy 14 (1), 177, 2022 | 4 | 2022 |
Investigation of memory-enhancing botanical mixture and their isolated compounds for inhibition of amyloid-β and tau aggregation S Baek, S Park, J Shin, JS Lee, HY Kim, G Han, YS Kim Applied biological chemistry 63 (1), 22, 2020 | 4 | 2020 |
Four-week individual caging of male ICR mice alters body composition without change in body mass J Shin, J Woo, Y Cho, YH Choi, NN Shin, YS Kim Scientific reports 8 (1), 1331, 2018 | 4 | 2018 |
Taurine-Carbohydrate Derivative Stimulates Fibrillogenesis of Amyloid-β and Reduce Alzheimer-Like Behaviors HY Kim, SH Yang, J Yoon, HC Jang, S Baek, J Shin, SH Kim, YS Kim Taurine 10, 225-232, 2017 | 4 | 2017 |
4-Acyl-3,4-dihydropyrrolo[1,2-a]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble … S Lee, A Dagar, I Cho, K Kim, IW Park, S Yoon, M Cha, J Shin, HY Kim, ... ACS Chemical Neuroscience 14 (11), 2016-2026, 2023 | 3 | 2023 |
Borrelidin from saltern-derived halophilic Nocardiopsis sp. dissociates amyloid-β and tau fibrils J Shin, SH Yang, YE Du, K Park, DW Kim, D Shin, J Kim, SH Kim, YK Kim, ... Journal of Alzheimer's Disease Reports 5 (1), 7-13, 2021 | 3 | 2021 |
Rhizolutin directly dissociates Aβ and tau aggregates and reduces apoptosis/inflammation related to Alzheimer’s disease J Shin, Y Kwon, K Nam, JS An, SH Yang, SH Hong, M Bae, K Moon, ... Alzheimer's & Dementia 17, e049661, 2021 | 1 | 2021 |