A gut-brain neural circuit for nutrient sensory transduction MM Kaelberer, KL Buchanan, ME Klein, BB Barth, MM Montoya, X Shen, ... Science 361 (6408), eaat5236, 2018 | 667 | 2018 |
Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis S Kulkarni, MA Micci, J Leser, C Shin, SC Tang, YY Fu, L Liu, Q Li, ... Proceedings of the National Academy of Sciences 114 (18), E3709-E3718, 2017 | 480* | 2017 |
The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation CSN Klose, T Mahlakõiv, JB Moeller, LC Rankin, AL Flamar, H Kabata, ... Nature 549 (7671), 282-286, 2017 | 477 | 2017 |
A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells P Bu, KY Chen, JH Chen, L Wang, J Walters, YJ Shin, JP Goerger, J Sun, ... Cell stem cell 12 (5), 602-615, 2013 | 392 | 2013 |
Targeted drug delivery to circulating tumor cells via platelet membrane-functionalized particles J Li, Y Ai, L Wang, P Bu, CC Sharkey, Q Wu, B Wun, S Roy, X Shen, ... Biomaterials 76, 52-65, 2016 | 271 | 2016 |
Aldolase B-mediated fructose metabolism drives metabolic reprogramming of colon cancer liver metastasis P Bu, KY Chen, K Xiang, C Johnson, SB Crown, N Rakhilin, Y Ai, L Wang, ... Cell metabolism 27 (6), 1249-1262. e4, 2018 | 226 | 2018 |
Method and apparatus for automatic layout of circuit structures S Mohan, X Shen US Patent 6,789,246, 2004 | 208 | 2004 |
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation S Sun, G Shi, H Sha, Y Ji, X Han, X Shu, H Ma, T Inoue, B Gao, H Kim, ... Nature cell biology 17 (12), 1546-1555, 2015 | 199 | 2015 |
A miR-34a-numb feedforward loop triggered by inflammation regulates asymmetric stem cell division in intestine and colon cancer P Bu, L Wang, KY Chen, T Srinivasan, PKL Murthy, KL Tung, AK Varanko, ... Cell stem cell 18 (2), 189-202, 2016 | 148 | 2016 |
Epigenetics and cancer metabolism C Johnson, MO Warmoes, X Shen, JW Locasale Cancer letters 356 (2), 309-314, 2015 | 136 | 2015 |
A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors AB Dohlman, J Klug, M Mesko, IH Gao, SM Lipkin, X Shen, ID Iliev Cell 185 (20), 3807-3822. e12, 2022 | 135 | 2022 |
A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division L Wang, P Bu, Y Ai, T Srinivasan, HJ Chen, K Xiang, SM Lipkin, X Shen Elife 5, e14620, 2016 | 129 | 2016 |
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β P Bu, L Wang, KY Chen, N Rakhilin, J Sun, A Closa, KL Tung, S King, ... Nature communications 6 (1), 6879, 2015 | 126 | 2015 |
Compensation for multimode fiber dispersion by adaptive optics X Shen, JM Kahn, MA Horowitz Optics letters 30 (22), 2985-2987, 2005 | 125 | 2005 |
The cancer microbiome atlas: a pan-cancer comparative analysis to distinguish tissue-resident microbiota from contaminants AB Dohlman, DA Mendoza, S Ding, M Gao, H Dressman, ID Iliev, ... Cell host & microbe 29 (2), 281-298. e5, 2021 | 117 | 2021 |
A recellularized human colon model identifies cancer driver genes HJ Chen, Z Wei, J Sun, A Bhattacharya, DJ Savage, R Serda, Y Mackeyev, ... Nature biotechnology 34 (8), 845-851, 2016 | 97 | 2016 |
Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis HJ Chen, R Edwards, S Tucci, P Bu, J Milsom, S Lee, W Edelmann, ... The Journal of clinical investigation 122 (9), 3184-3196, 2012 | 91 | 2012 |
An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation MH Tan, JB Kozdon, X Shen, L Shapiro, HH McAdams Proceedings of the National Academy of Sciences 107 (44), 18985-18990, 2010 | 89 | 2010 |
Intravital Imaging of Mouse Embryos qiang science, 0 | 83* | |
The class I HDAC inhibitor MGCD0103 induces cell cycle arrest and apoptosis in colon cancer initiating cells by upregulating Dickkopf-1 and non-canonical Wnt signaling S Sikandar, D Dizon, X Shen, Z Li, J Besterman, SM Lipkin Oncotarget 1 (7), 596, 2010 | 82 | 2010 |