Opher Gileadi
Opher Gileadi
Principal Investigator, SGC, University of Oxford
Adresse e-mail validée de sgc.ox.ac.uk
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Protein production and purification
S Gräslund, P Nordlund, J Weigelt, BM Hallberg, J Bray, O Gileadi, ...
Nature methods 5 (2), 135, 2008
Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study
NA Burgess-Brown, S Sharma, F Sobott, C Loenarz, U Oppermann, ...
Protein expression and purification 59 (1), 94-102, 2008
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity
SS Ng, KL Kavanagh, MA McDonough, D Butler, ES Pilka, BMR Lienard, ...
Nature 448 (7149), 87-91, 2007
An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae
MS Kobor, J Archambault, W Lester, FCP Holstege, O Gileadi, DB Jansma, ...
Molecular cell 4 (1), 55-62, 1999
Scanning electron microscopy of cells and tissues under fully hydrated conditions
S Thiberge, A Nechushtan, D Sprinzak, O Gileadi, V Behar, O Zik, ...
Proceedings of the National Academy of Sciences 101 (10), 3346-3351, 2004
High-throughput production of human proteins for crystallization: the SGC experience
P Savitsky, J Bray, CDO Cooper, BD Marsden, P Mahajan, ...
Journal of structural biology 172 (1), 3-13, 2010
CTD kinase associated with yeast RNA polymerase II initiation factor b
WJ Feaver, O Gileadi, Y Li, RD Kornberg
Cell 67 (6), 1223-1230, 1991
Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states
CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ...
Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
P Canning, CDO Cooper, T Krojer, JW Murray, ACW Pike, A Chaikuad, ...
Journal of Biological Chemistry 288 (11), 7803-7814, 2013
Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria
C Johansson, KL Kavanagh, O Gileadi, U Oppermann
Journal of Biological Chemistry 282 (5), 3077-3082, 2007
Compaction of single DNA molecules induced by binding of integration host factor (IHF)
BMJ Ali, R Amit, I Braslavsky, AB Oppenheim, O Gileadi, J Stavans
Proceedings of the National Academy of Sciences 98 (19), 10658-10663, 2001
Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases
D Chen, M Vollmar, MN Rossi, C Phillips, R Kraehenbuehl, D Slade, ...
Journal of Biological Chemistry 286 (15), 13261-13271, 2011
Human SNM1A and XPF–ERCC1 collaborate to initiate DNA interstrand cross-link repair
AT Wang, B Sengerová, E Cattell, T Inagawa, JM Hartley, K Kiakos, ...
Genes & development 25 (17), 1859-1870, 2011
Structure of the human RECQ1 helicase reveals a putative strand-separation pin
ACW Pike, B Shrestha, V Popuri, N Burgess-Brown, L Muzzolini, ...
Proceedings of the National Academy of Sciences 106 (4), 1039-1044, 2009
Crystal structures of the catalytic domain of human soluble guanylate cyclase
CK Allerston, F von Delft, O Gileadi
PloS one 8 (3), e57644, 2013
A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells
GH Nguyen, TS Dexheimer, AS Rosenthal, WK Chu, DK Singh, ...
Chemistry & biology 20 (1), 55-62, 2013
Cak1 is required for Kin28 phosphorylation and activation in vivo
FH Espinoza, A Farrell, JL Nourse, HM Chamberlin, O Gileadi, ...
Molecular and Cellular Biology 18 (11), 6365-6373, 1998
Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities
D Busso, A Keriel, B Sandrock, A Poterszman, O Gileadi, JM Egly
Journal of Biological Chemistry 275 (30), 22815-22823, 2000
Objective-type dark-field illumination for scattering from microbeads
I Braslavsky, R Amit, BMJ Ali, O Gileadi, A Oppenheim, J Stavans
Applied optics 40 (31), 5650-5657, 2001
Cloning of a subunit of yeast RNA polymerase II transcription factor b and CTD kinase
O Gileadi, WJ Feaver, RD Kornberg
Science 257 (5075), 1389-1392, 1992
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