Jeppe Trudslev Pedersen

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Kaare TeilumDepartment of Biology, University of CopenhagenVerified email at bio.ku.dk
Jesper OstergaardAssociate Professor, Department of Pharmacy, University of CopenhagenVerified email at sund.ku.dk
Lars HemmingsenDepartment of Chemistry, University of CopenhagenVerified email at chem.ku.dk
Peter FallerProfessor of Chemistry, University of StrasbourgVerified email at unistra.fr
Noemi RozlosnikSenior advisor at Eir-Diagnostics ApSVerified email at norizon2023.com
bente gammelgaardProfessor of Analytical Chemistry University of CopenhagenVerified email at sund.ku.dk
CUVILLIER OlivierLCC UPR 8241 CNRSVerified email at inserm.fr
Christopher DobsonUniversity of CambridgeVerified email at cam.ac.uk
Jakob R. WintherLinderstøm-Lang Centre for Protein Science, Department of Biology, University of CopenhagenVerified email at bio.ku.dk
Emmanuel GrasCNRS Researcher, LCC (CNRS), ITAV (CNRS/UPS), TMBI (Univ. Toulouse)Verified email at lcc-toulouse.fr
Emmanuel GuillonProf. Chimie Environnementale, Univ. Reims Champagne-ArdenneVerified email at univ-reims.fr
Tuomas KnowlesProfessor of Physical Chemistry and Biophysics, University of CambridgeVerified email at cam.ac.uk
Thomas C T MichaelsETH ZurichVerified email at biol.ethz.ch
J.G. CorreiaSenior Researcher, IST-C2TN, Universidade de Lisboa, PortugalVerified email at tecnico.ulisboa.pt
Peter W. ThulstrupDepartment of Chemistry, University of CopenhagenVerified email at chem.ku.dk

Jeppe Trudslev Pedersen

Project Manager | Early Research | Novo Nordisk

Verified email at novonordisk.com

Biophysics Protein Aggregation Kinetics Protein Formulation


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Cu (II) mediates kinetically distinct, non-amyloidogenic aggregation of amyloid-β peptides JT Pedersen, J Østergaard, N Rozlosnik, B Gammelgaard, ... Journal of Biological Chemistry 286 (30), 26952-26963, 2011	144	2011
Analysis of Protein Aggregation in Neurodegenerative Disease JT Pedersen, NHH Heegaard Analytical Chemistry, 2013	121	2013
Rapid formation of a preoligomeric peptide–metal–peptide complex following copper (II) binding to amyloid β peptides JT Pedersen, K Teilum, NHH Heegaard, J Østergaard, HW Adolph, ... Angewandte Chemie 11 (123), 2580-2583, 2011	85	2011
Amyloid-β and α-synuclein decrease the level of metal-catalyzed reactive oxygen species by radical scavenging and redox silencing JT Pedersen, SW Chen, CB Borg, S Ness, JM Bahl, NHH Heegaard, ... Journal of the American Chemical Society 138 (12), 3966-3969, 2016	80	2016
Rapid Exchange of Metal between Zn₇–Metallothionein-3 and Amyloid-β Peptide Promotes Amyloid-Related Structural Changes JT Pedersen, C Hureau, L Hemmingsen, NHH Heegaard, J Østergaard, ... Biochemistry 51 (8), 1697-1706, 2012	74	2012
The pK_a Value and Accessibility of Cysteine Residues Are Key Determinants for Protein Substrate Discrimination by Glutaredoxin KS Jensen, JT Pedersen, JR Winther, K Teilum Biochemistry 53 (15), 2533-2540, 2014	42	2014
A new water-soluble Cu (II) chelator that retrieves Cu from Cu (Amyloid-β) species, stops associated ROS production and prevents Cu (II) induced Aβ aggregation S Noël, F Perez, JT Pedersen, B Alies, S Ladeira, S Sayen, E Guillon, ... Journal of Inorganic Biochemistry 117, 322-325, 2012	42	2012
Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties. M Jensen, A Canning, S Chiha, P Bouquerel, JT Pedersen, J Østergaard, ... Chemistry (Weinheim an der Bergstrasse, Germany) 18 (16), 4836-4839, 2012	36	2012
Aggregation‐Prone Amyloid‐β⋅ CuII Species Formed on the Millisecond Timescale under Mildly Acidic Conditions JT Pedersen, CB Borg, TCT Michaels, TPJ Knowles, P Faller, K Teilum, ... ChemBioChem 16 (9), 1293-1297, 2015	29	2015
Affinity capillary electrophoresis for identification and investigation of human Gc‐globulin (vitamin D‐binding protein) and its isoforms interacting with G‐actin JT Pedersen, J Østergaard, G Houen, NHH Heegaard Electrophoresis 29 (8), 1723-1733, 2008	26	2008
Nanosecond dynamics at protein metal sites: an application of perturbed angular correlation (PAC) of γ-rays spectroscopy S Chakraborty, S Pallada, JT Pedersen, A Jancso, JG Correia, ... Accounts of chemical research 50 (9), 2225-2232, 2017	9	2017
pH dependence of amyloid-beta-Cu (II) binding and oligomerization kinetics JT Pedersen, CB Borg, K Teilum, L Hemmingsen JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S755-S755, 2014		2014
Binding of Cu2+ to the islet amyloid polypeptide (IAPP) J Andersen-Usaj, AC Bonde, J Pihl, MLF Thomsen, M Shavit, ... JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S812-S812, 2014		2014
Islet amyloid polypeptide (IAPP)-Structural effects of Zn2+ M Shavit, AC Bonde, J Pihl, MLF Thomsen, JT Pedersen, ... JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S813-S813, 2014		2014
Role of Cu 2+ in oligomerization and aggregation of alzheimer's amyloid-ß peptides JT Pedersen PhD thesis, University of Copenhagen, 2011		2011

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