| Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines JS Damiano, AE Cress, LA Hazlehurst, AA Shtil, WS Dalton Blood, the Journal of the American Society of Hematology 93 (5), 1658-1667, 1999 | 1175 | 1999 |
| The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance MB Meads, LA Hazlehurst, WS Dalton Clinical Cancer Research 14 (9), 2519-2526, 2008 | 623 | 2008 |
| Adhesion to fibronectin via β1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR) LA Hazlehurst, JS Damiano, I Buyuksal, WJ Pledger, WS Dalton Oncogene 19 (38), 4319-4327, 2000 | 463 | 2000 |
| Role of the tumor microenvironment in mediating de novo resistance to drugs and physiological mediators of cell death LA Hazlehurst, TH Landowski, WS Dalton Oncogene 22 (47), 7396-7402, 2003 | 267 | 2003 |
| β1 integrin adhesion enhances IL-6–mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation KH Shain, DN Yarde, MB Meads, M Huang, R Jove, LA Hazlehurst, ... Cancer research 69 (3), 1009-1015, 2009 | 240 | 2009 |
| ABCG2 expression, function, and promoter methylation in human multiple myeloma JG Turner, JL Gump, C Zhang, JM Cook, D Marchion, L Hazlehurst, ... Blood 108 (12), 3881-3889, 2006 | 237 | 2006 |
| Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and γ … JS Damiano, LA Hazlehurst, WS Dalton Leukemia 15 (8), 1232-1239, 2001 | 228 | 2001 |
| Mechanisms associated with cell adhesion mediated drug resistance (CAM-DR) in hematopoietic malignancies LA Hazlehurst, WS Dalton Cancer and Metastasis Reviews 20, 43-50, 2001 | 198 | 2001 |
| Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance NN Bewry, RR Nair, MF Emmons, D Boulware, J Pinilla-Ibarz, ... Molecular cancer therapeutics 7 (10), 3169-3175, 2008 | 191 | 2008 |
| Reduction in drug-induced DNA double-strand breaks associated with β1 integrin–mediated adhesion correlates with drug resistance in U937 cells LA Hazlehurst, N Valkov, L Wisner, JA Storey, D Boulware, DM Sullivan, ... Blood, The Journal of the American Society of Hematology 98 (6), 1897-1903, 2001 | 179 | 2001 |
| Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line LA Hazlehurst, NE Foley, MC Gleason-Guzman, MP Hacker, AE Cress, ... Cancer research 59 (5), 1021-1028, 1999 | 177 | 1999 |
| Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model LA Hazlehurst, SA Enkemann, CA Beam, RF Argilagos, J Painter, ... Cancer research 63 (22), 7900-7906, 2003 | 169 | 2003 |
| The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells Q Chen, PC Van der Sluis, D Boulware, LA Hazlehurst, WS Dalton Blood 106 (2), 698-705, 2005 | 163 | 2005 |
| Pharmacology: principles and practice M Hacker, WS Messer, KA Bachmann Academic Press, 2009 | 162 | 2009 |
| Proteomic contributions to personalized cancer care JM Koomen, EB Haura, G Bepler, R Sutphen, ER Remily-Wood, ... Molecular & Cellular Proteomics 7 (10), 1780-1794, 2008 | 139 | 2008 |
| Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non … T Lwin, LA Hazlehurst, S Dessureault, R Lai, W Bai, E Sotomayor, ... Blood, The Journal of the American Society of Hematology 110 (5), 1631-1638, 2007 | 125 | 2007 |
| Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma DN Yarde, V Oliveira, L Mathews, X Wang, A Villagra, D Boulware, ... Cancer research 69 (24), 9367-9375, 2009 | 118 | 2009 |
| β1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells LA Hazlehurst, RF Argilagos, WS Dalton British journal of haematology 136 (2), 269-275, 2007 | 117 | 2007 |
| Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-κB (RelB/p52) in non-Hodgkin's … T Lwin, LA Hazlehurst, Z Li, S Dessureault, E Sotomayor, LC Moscinski, ... Leukemia 21 (7), 1521-1531, 2007 | 111 | 2007 |
| Cell adhesion to fibronectin (CAM-DR) influences acquired mitoxantrone resistance in U937 cells LA Hazlehurst, RF Argilagos, M Emmons, D Boulware, CA Beam, ... Cancer research 66 (4), 2338-2345, 2006 | 105 | 2006 |
