| Redesign of the coenzyme specificity of a dehydrogenase by protein engineering NS Scrutton, A Berry, RN Perham Nature 343 (6253), 38-43, 1990 | 902 | 1990 |
| Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades FG Mutti, T Knaus, NS Scrutton, M Breuer, NJ Turner Science 349 (6255), 1525-1529, 2015 | 405 | 2015 |
| Atomic description of an enzyme reaction dominated by proton tunneling L Masgrau, A Roujeinikova, LO Johannissen, P Hothi, J Basran, ... Science 312 (5771), 237-241, 2006 | 399 | 2006 |
| Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases HS Toogood, JM Gardiner, NS Scrutton ChemCatChem 2 (8), 892-914, 2010 | 328 | 2010 |
| Cation-π bonding and amino-aromatic interactions in the biomolecular recognition of substituted ammonium ligands NS Scrutton, ARC Raine Biochemical Journal 319 (1), 1-8, 1996 | 314 | 1996 |
| Good vibrations in enzyme-catalysed reactions S Hay, NS Scrutton Nature chemistry 4 (3), 161-168, 2012 | 310 | 2012 |
| Enzymatic H-transfer requires vibration-driven extreme tunneling J Basran, MJ Sutcliffe, NS Scrutton Biochemistry 38 (10), 3218-3222, 1999 | 289 | 1999 |
| Building a global alliance of biofoundries N Hillson, M Caddick, Y Cai, JA Carrasco, MW Chang, NC Curach, ... Nature communications 10 (1), 2040, 2019 | 274 | 2019 |
| Covalent attachment of flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) to enzymes: the current state of affairs M Mewies, WS McIntire, NS Scrutton Protein Science 7 (1), 7-20, 1998 | 270 | 1998 |
| Discovery, characterization, engineering, and applications of ene-reductases for industrial biocatalysis HS Toogood, NS Scrutton ACS catalysis 8 (4), 3532-3549, 2018 | 234 | 2018 |
| Biotransformation of explosives by the old yellow enzyme family of flavoproteins RE Williams, DA Rathbone, NS Scrutton, NC Bruce Applied and environmental microbiology 70 (6), 3566-3574, 2004 | 231 | 2004 |
| New cofactor supports α, β-unsaturated acid decarboxylation via 1, 3-dipolar cycloaddition KAP Payne, MD White, K Fisher, B Khara, SS Bailey, D Parker, ... Nature 522 (7557), 497-501, 2015 | 226 | 2015 |
| An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals P Carbonell, AJ Jervis, CJ Robinson, C Yan, M Dunstan, N Swainston, ... Communications biology 1 (1), 66, 2018 | 223 | 2018 |
| What’s in a covalent bond? On the role and formation of covalently bound flavin cofactors DPHM Heuts, NS Scrutton, WS McIntire, MW Fraaije The FEBS journal 276 (13), 3405-3427, 2009 | 216 | 2009 |
| UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis MD White, KAP Payne, K Fisher, SA Marshall, D Parker, NJW Rattray, ... Nature 522 (7557), 502-506, 2015 | 199 | 2015 |
| Better than nature: nicotinamide biomimetics that outperform natural coenzymes T Knaus, CE Paul, CW Levy, S De Vries, FG Mutti, F Hollmann, ... Journal of the American Chemical Society 138 (3), 1033-1039, 2016 | 178 | 2016 |
| A new conceptual framework for enzyme catalysis: Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes MJ Sutcliffe, NS Scrutton European Journal of Biochemistry 269 (13), 3096-3102, 2002 | 172 | 2002 |
| Biodiversity of cytochrome P450 redox systems KJ McLean, M Sabri, KR Marshall, RJ Lawson, DG Lewis, D Clift, ... Biochemical Society Transactions 33 (4), 796-801, 2005 | 166 | 2005 |
| The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase R Neeli, HM Girvan, A Lawrence, MJ Warren, D Leys, NS Scrutton, ... FEBS letters 579 (25), 5582-5588, 2005 | 160 | 2005 |
| New developments in ‘ene’-reductase catalysed biological hydrogenations HS Toogood, NS Scrutton Current opinion in chemical biology 19, 107-115, 2014 | 159 | 2014 |
