Hugo M. Horlings
Hugo M. Horlings
MD PhD, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
RA Gupta, N Shah, KC Wang, J Kim, HM Horlings, DJ Wong, MC Tsai, ...
Nature 464 (7291), 1071-1076, 2010
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ...
Cancer cell 12 (4), 395-402, 2007
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ...
Nature genetics 43 (7), 621-629, 2011
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
K Stemke-Hale, AM Gonzalez-Angulo, A Lluch, RM Neve, WL Kuo, ...
Cancer research 68 (15), 6084-6091, 2008
Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas
B Kreike, M van Kouwenhove, H Horlings, B Weigelt, H Peterse, ...
Breast Cancer Research 9 (5), R65, 2007
Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
M Persson, Y Andrén, J Mark, HM Horlings, F Persson, G Stenman
Proceedings of the National Academy of Sciences 106 (44), 18740-18744, 2009
Refinement of breast cancer classification by molecular characterization of histological special types
B Weigelt, HM Horlings, B Kreike, MM Hayes, M Hauptmann, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008
MicroRNA sequence and expression analysis in breast tumors by deep sequencing
TA Farazi, HM Horlings, J Jelle, A Mihailovic, H Halfwerk, P Morozov, ...
Cancer research 71 (13), 4443-4453, 2011
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
N Turner, MB Lambros, HM Horlings, A Pearson, R Sharpe, R Natrajan, ...
Oncogene 29 (14), 2013-2023, 2010
Genetic regulators of large-scale transcriptional signatures in cancer
AS Adler, M Lin, H Horlings, DSA Nuyten, MJ van de Vijver, HY Chang
Nature genetics 38 (4), 421-430, 2006
Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis
LCW Vredeveld, PA Possik, MA Smit, K Meissl, C Michaloglou, ...
Genes & development 26 (10), 1055-1069, 2012
AACR Project GENIE: powering precision medicine through an international consortium
AACR Project Genie Consortium
Cancer discovery 7 (8), 818-831, 2017
Cancer-associated mutations in endometriosis without cancer
MS Anglesio, N Papadopoulos, A Ayhan, TM Nazeran, M Noë, ...
New England Journal of Medicine 376 (19), 1835-1848, 2017
A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe
JWR Hovius, B de Wever, M Sohne, MC Brouwer, J Coumou, ...
Lancet 382 (9892), 658, 2013
Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary
HM Horlings, RK van Laar, JM Kerst, HH Helgason, J Wesseling, ...
Journal of Clinical Oncology 26 (27), 4435-4441, 2008
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators
R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ...
Nature 549 (7670), 106-110, 2017
A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer
F Reyal, MH van Vliet, NJ Armstrong, HM Horlings, KE de Visser, M Kok, ...
Breast Cancer Research 10 (6), R93, 2008
High prevalence of oncogenic MYD88 and CD79B mutations in diffuse large B-cell lymphomas presenting at immune-privileged sites
W Kraan, HM Horlings, M van Keimpema, EJM Schilder-Tol, MECM Oud, ...
Blood cancer journal 3 (9), e139-e139, 2013
Assessing tumor infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology …
S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ...
Advances in anatomic pathology 24 (6), 311, 2017
Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis
CJ Desmet, T Gallenne, A Prieur, F Reyal, NL Visser, BS Wittner, MA Smit, ...
Proceedings of the National Academy of Sciences 110 (13), 5139-5144, 2013
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