Hugo M. Horlings
Hugo M. Horlings
MD PhD, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Adresse e-mail validée de nki.nl - Page d'accueil
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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
RA Gupta, N Shah, KC Wang, J Kim, HM Horlings, DJ Wong, MC Tsai, ...
Nature 464 (7291), 1071-1076, 2010
44112010
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ...
Cancer cell 12 (4), 395-402, 2007
15752007
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ...
Nature genetics 43 (7), 621-629, 2011
9952011
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
K Stemke-Hale, AM Gonzalez-Angulo, A Lluch, RM Neve, WL Kuo, ...
Cancer research 68 (15), 6084-6091, 2008
9492008
Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas
B Kreike, M van Kouwenhove, H Horlings, B Weigelt, H Peterse, ...
Breast Cancer Research 9 (5), R65, 2007
7162007
Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
M Persson, Y Andrén, J Mark, HM Horlings, F Persson, G Stenman
Proceedings of the National Academy of Sciences 106 (44), 18740-18744, 2009
6112009
Refinement of breast cancer classification by molecular characterization of histological special types
B Weigelt, HM Horlings, B Kreike, MM Hayes, M Hauptmann, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008
5442008
MicroRNA sequence and expression analysis in breast tumors by deep sequencing
TA Farazi, HM Horlings, J Jelle, A Mihailovic, H Halfwerk, P Morozov, ...
Cancer research 71 (13), 4443-4453, 2011
3592011
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
N Turner, MB Lambros, HM Horlings, A Pearson, R Sharpe, R Natrajan, ...
Oncogene 29 (14), 2013-2023, 2010
3592010
AACR Project GENIE: powering precision medicine through an international consortium
AACR Project Genie Consortium
Cancer discovery 7 (8), 818-831, 2017
2772017
Genetic regulators of large-scale transcriptional signatures in cancer
AS Adler, M Lin, H Horlings, DSA Nuyten, MJ van de Vijver, HY Chang
Nature genetics 38 (4), 421-430, 2006
2572006
Cancer-associated mutations in endometriosis without cancer
MS Anglesio, N Papadopoulos, A Ayhan, TM Nazeran, M Noë, ...
New England Journal of Medicine 376 (19), 1835-1848, 2017
2492017
Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis
LCW Vredeveld, PA Possik, MA Smit, K Meissl, C Michaloglou, ...
Genes & development 26 (10), 1055-1069, 2012
2432012
A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe
JWR Hovius, B de Wever, M Sohne, MC Brouwer, J Coumou, ...
Lancet 382 (9892), 658, 2013
2042013
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators
R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ...
Nature 549 (7670), 106-110, 2017
1942017
Assessing tumor infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology …
S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ...
Advances in anatomic pathology 24 (6), 311, 2017
1812017
Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary
HM Horlings, RK van Laar, JM Kerst, HH Helgason, J Wesseling, ...
Journal of Clinical Oncology 26 (27), 4435-4441, 2008
1802008
Dysfunctional CD8 T cells form a proliferative, dynamically regulated compartment within human melanoma
H Li, AM van der Leun, I Yofe, Y Lubling, D Gelbard-Solodkin, ...
Cell 176 (4), 775-789. e18, 2019
1732019
Assessing tumor infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology …
S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ...
Advances in anatomic pathology 24 (5), 235, 2017
1592017
High prevalence of oncogenic MYD88 and CD79B mutations in diffuse large B-cell lymphomas presenting at immune-privileged sites
W Kraan, HM Horlings, M van Keimpema, EJM Schilder-Tol, MECM Oud, ...
Blood cancer journal 3 (9), e139-e139, 2013
1532013
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