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Kameron V. Kilchrist
Kameron V. Kilchrist
Senior Scientist, Kodiak Sciences
Adresse e-mail validée de kodiak.com - Page d'accueil
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Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers
M Miteva, KC Kirkbride, KV Kilchrist, TA Werfel, H Li, CE Nelson, ...
Biomaterials 38, 97-107, 2015
1532015
Endosomolytic and tumor-penetrating mesoporous silica nanoparticles for siRNA/miRNA combination cancer therapy
Y Wang, Y Xie, KV Kilchrist, J Li, CL Duvall, D Oupický
ACS applied materials & interfaces 12 (4), 4308-4322, 2020
1212020
Zwitterionic nanocarrier surface chemistry improves siRNA tumor delivery and silencing activity relative to polyethylene glycol
MA Jackson, TA Werfel, EJ Curvino, F Yu, TE Kavanaugh, SM Sarett, ...
ACS nano 11 (6), 5680-5696, 2017
1102017
Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing
SM Sarett, TA Werfel, L Lee, MA Jackson, KV Kilchrist, D Brantley-Sieders, ...
Proceedings of the National Academy of Sciences 114 (32), E6490-E6497, 2017
1082017
Gal8 visualization of endosome disruption predicts carrier-mediated biologic drug intracellular bioavailability
KV Kilchrist, SC Dimobi, MA Jackson, BC Evans, TA Werfel, EA Dailing, ...
ACS nano 13 (2), 1136-1152, 2019
1042019
Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival
TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, LH Lee, ...
Cancer research 78 (7), 1845-1858, 2018
752018
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, ...
Nature Communications 10 (1), 5012, 2019
632019
Porous silicon and polymer nanocomposites for delivery of peptide nucleic acids as anti-microRNA therapies
KR Beavers, TA Werfel, T Shen, TE Kavanaugh, KV Kilchrist, JW Mares, ...
Advanced Materials (Deerfield Beach, Fla.) 28 (36), 7984, 2016
562016
Endosomolytic nano-polyplex platform technology for cytosolic peptide delivery to inhibit pathological vasoconstriction
BC Evans, KM Hocking, KV Kilchrist, ES Wise, CM Brophy, CL Duvall
ACS nano 9 (6), 5893-5907, 2015
542015
MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia
BC Evans, KM Hocking, MJ Osgood, I Voskresensky, J Dmowska, ...
Science translational medicine 7 (291), 291ra95-291ra95, 2015
522015
Tumor-Penetrating Mesoporous Silica Nanoparticles for siRNA/miRNA Combination Cancer Therapy. ACS Appl. Mater
Y Wang, Y Xie, KV Kilchrist, J Li, CL Duvall, DE Oupický
Interfaces 12, 4308-4322, 2020
432020
Mechanism of enhanced cellular uptake and cytosolic retention of MK2 inhibitory peptide nano-polyplexes
KV Kilchrist, BC Evans, CM Brophy, CL Duvall
Cellular and molecular bioengineering 9, 368-381, 2016
352016
Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles
SM Sarett, KV Kilchrist, M Miteva, CL Duvall
Journal of Biomedical Materials Research Part A 103 (9), 3107-3116, 2015
322015
Thiol‐acrylate nanocomposite foams for critical size bone defect repair: A novel biomaterial
L Garber, C Chen, KV Kilchrist, C Bounds, JA Pojman, D Hayes
Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2013
322013
Amphiphilic polyelectrolyte graft copolymers enhance the activity of cyclic dinucleotide STING agonists
DC Nguyen, D Shae, HM Pagendarm, KW Becker, M Wehbe, KV Kilchrist, ...
Advanced healthcare materials 10 (2), 2001056, 2021
172021
Genetically encoded split-luciferase biosensors to measure endosome disruption rapidly in live cells
KV Kilchrist, JW Tierney, CL Duvall
ACS sensors 5 (7), 1929-1936, 2020
142020
Excipients for the lyoprotection of MAPKAP kinase 2 inhibitory peptide nano-polyplexes
AJ Mukalel, BC Evans, KV Kilchrist, EA Dailing, B Burdette, ...
Journal of controlled release 282, 110-119, 2018
142018
Hydrolytic charge‐reversal of PEG ylated polyplexes enhances intracellular un‐packaging and activity of si RNA
TA Werfel, C Swain, CE Nelson, KV Kilchrist, BC Evans, M Miteva, ...
Journal of Biomedical Materials Research Part A 104 (4), 917-927, 2016
142016
Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis
NA Mignemi, PM McClatchey, KV Kilchrist, IM Williams, BA Millis, ...
American Journal of Physiology-Endocrinology and Metabolism 316 (6), E1012-E1023, 2019
132019
Microparticle depots for controlled and sustained release of endosomolytic nanoparticles
KM Garland, S Sevimli, KV Kilchrist, CL Duvall, RS Cook, JT Wilson
Cellular and Molecular Bioengineering 12, 429-442, 2019
122019
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