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Rafael Arrojo e Drigo
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Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function
G Yu, A Tzouvelekis, R Wang, JD Herazo-Maya, GH Ibarra, A Srivastava, ...
Nature medicine 24 (1), 39-49, 2018
2672018
Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signaling
RA e Drigo, TL Fonseca, JPS Werneck-de-Castro, AC Bianco
Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (7), 3956-3964, 2013
1652013
Coordination of hypothalamic and pituitary T3 production regulates TSH expression
TL Fonseca, M Correa-Medina, MPO Campos, G Wittmann, ...
The Journal of clinical investigation 123 (4), 1492-1500, 2013
1572013
Type 2 deiodinase at the crossroads of thyroid hormone action
RA e Drigo, AC Bianco
The international journal of biochemistry & cell biology 43 (10), 1432-1441, 2011
1152011
Age mosaicism across multiple scales in adult tissues
RA e Drigo, V Lev-Ram, S Tyagi, R Ramachandra, T Deerinck, ...
Cell metabolism 30 (2), 343-351. e3, 2019
1062019
New insights into the architecture of the islet of Langerhans: a focused cross-species assessment
R Arrojo e Drigo, Y Ali, J Diez, DK Srinivasan, PO Berggren, BO Boehm
Diabetologia 58, 2218-2228, 2015
1062015
The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase
AM Zavacki, R Arrojo e Drigo, BCG Freitas, M Chung, JW Harney, P Egri, ...
Molecular and cellular biology 29 (19), 5339-5347, 2009
882009
Young capillary vessels rejuvenate aged pancreatic islets
J Almaça, J Molina, R Arrojo e Drigo, MH Abdulreda, WB Jeon, ...
Proceedings of the National Academy of Sciences 111 (49), 17612-17617, 2014
872014
Structural basis for delta cell paracrine regulation in pancreatic islets
R Arrojo e Drigo, S Jacob, CF García-Prieto, X Zheng, M Fukuda, ...
Nature communications 10 (1), 3700, 2019
852019
Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells
BH Toyama, R Arrojo e Drigo, V Lev-Ram, R Ramachandra, TJ Deerinck, ...
Journal of Cell Biology 218 (2), 433-444, 2019
792019
Inhibition of the type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment
ML Rosene, G Wittmann, R Arrojo e Drigo, PS Singru, RM Lechan, ...
Endocrinology 151 (12), 5961-5970, 2010
772010
Dexamethasone reduces energy expenditure and increases susceptibility to diet‐induced obesity in mice
R Poggioli, CB Ueta, RA Drigo, M Castillo, TL Fonseca, AC Bianco
Obesity 21 (9), E415-E420, 2013
672013
Mice with impaired extrathyroidal thyroxine to 3, 5, 3′-triiodothyronine conversion maintain normal serum 3, 5, 3′-triiodothyronine concentrations
MA Christoffolete, R Arrojo e Drigo, F Gazoni, SM Tente, V Goncalves, ...
Endocrinology 148 (3), 954-960, 2007
672007
Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism
S Jo, I Kalló, Z Bardóczi, RA e Drigo, A Zeöld, Z Liposits, A Oliva, ...
Journal of Neuroscience 32 (25), 8491-8500, 2012
592012
A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons
I Kalló, P Mohácsik, B Vida, A Zeöld, Z Bardóczi, AM Zavacki, E Farkas, ...
PloS one 7 (6), e37860, 2012
562012
Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state
XQ Dai, J Camunas-Soler, LJB Briant, T Dos Santos, AF Spigelman, ...
Cell Metabolism 34 (2), 256-268. e5, 2022
482022
Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury
Z Ma, NK Lytle, B Chen, N Jyotsana, SW Novak, CJ Cho, L Caplan, ...
Gastroenterology 162 (2), 604-620. e20, 2022
462022
The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure
WS da-Silva, S Ribich, RA e Drigo, M Castillo, ME Patti, AC Bianco
FEBS letters 585 (3), 539-544, 2011
422011
Pancreatic Islet Blood Flow Dynamics in Primates
J Diez, R Arrojo e Drigo, X Zheng, OV Stelmashenko, M Chua, ...
Cell Reports 20, 1490-1501, 2017
342017
Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis
R Arrojo e Drigo, TL Fonseca, M Castillo, M Salathe, G Simovic, ...
Molecular Endocrinology 25 (12), 2065-2075, 2011
312011
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