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Arne Ostman
Arne Ostman
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High interstitial fluid pressure—an obstacle in cancer therapy
CH Heldin, K Rubin, K Pietras, A Östman
Nature Reviews Cancer 4 (10), 806-813, 2004
23632004
Protein detection using proximity-dependent DNA ligation assays
S Fredriksson, M Gullberg, J Jarvius, C Olsson, K Pietras, ...
Nature biotechnology 20 (5), 473-477, 2002
16612002
Hallmarks of cancer: interactions with the tumor stroma
K Pietras, A Östman
Experimental cell research 316 (8), 1324-1331, 2010
14762010
Signal transduction via platelet-derived growth factor receptors
CH Heldin, A Östman, L Rönnstrand
Biochimica et Biophysica Acta (BBA)-reviews on cancer 1378 (1), F79-F113, 1998
10801998
PDGF-C is a new protease-activated ligand for the PDGF α-receptor
X Li, A Pontén, K Aase, L Karlsson, A Abramsson, M Uutela, G Bäckström, ...
Nature cell biology 2 (5), 302-309, 2000
8302000
Protein-tyrosine phosphatases and cancer
A Östman, C Hellberg, FD Böhmer
Nature Reviews Cancer 6 (4), 307-320, 2006
8152006
PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor
E Bergsten, M Uutela, X Li, K Pietras, A Östman, CH Heldin, K Alitalo, ...
Nature cell biology 3 (5), 512-516, 2001
7742001
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall
P Lindblom, H Gerhardt, S Liebner, A Abramsson, M Enge, M Hellström, ...
Genes & development 17 (15), 1835-1840, 2003
7542003
Cancer-associated fibroblasts and tumor growth–bystanders turning into key players
A Östman, M Augsten
Current opinion in genetics & development 19 (1), 67-73, 2009
6692009
Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.
CH Heldin, G Bäckström, A Ostman, A Hammacher, L Rönnstrand, ...
The EMBO journal 7 (5), 1387-1393, 1988
6221988
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
K Pietras, A Ostman, M Sjöquist, E Buchdunger, RK Reed, CH Heldin, ...
Cancer research 61 (7), 2929-2934, 2001
5772001
PDGF receptors as cancer drug targets
K Pietras, T Sjöblom, K Rubin, CH Heldin, A Östman
Cancer cell 3 (5), 439-443, 2003
5702003
Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy
K Pietras, K Rubin, T Sjöblom, E Buchdunger, M Sjöquist, CH Heldin, ...
Cancer research 62 (19), 5476-5484, 2002
5572002
Inhibitory DNA ligands to platelet-derived growth factor B-chain
LS Green, D Jellinek, R Jenison, A Östman, CH Heldin, N Janjic
Biochemistry 35 (45), 14413-14424, 1996
5561996
Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases
A Östman, FD Böhmer
Trends in cell biology 11 (6), 258-266, 2001
4472001
cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules
L Claesson-Welsh, A Eriksson, A Morén, L Severinsson, B Ek, A Ostman, ...
Molecular and cellular biology 8 (8), 3476-3486, 1988
4261988
PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
A Östman
Cytokine & growth factor reviews 15 (4), 275-286, 2004
4082004
A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.
A Hammacher, U Hellman, A Johnsson, A Ostman, K Gunnarsson, ...
Journal of Biological Chemistry 263 (31), 16493-16498, 1988
3941988
The dermatofibrosarcoma protuberans-associated collagen type Iα1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to …
A Shimizu, KP O’Brien, T Sjöblom, K Pietras, E Buchdunger, VP Collins, ...
Cancer research 59 (15), 3719-3723, 1999
3471999
PDGF and vessel maturation
C Hellberg, A Östman, CH Heldin
Angiogenesis inhibition, 103-114, 2010
3442010
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