Padraic G. Fallon
Padraic G. Fallon
School of Medicine, Trinity College Dublin, Ireland.
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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
DR Neill, SH Wong, A Bellosi, RJ Flynn, M Daly, TKA Langford, C Bucks, ...
Nature 464 (7293), 1367-1370, 2010
A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis
M Salimi, JL Barlow, SP Saunders, L Xue, D Gutowska-Owsiak, X Wang, ...
Journal of Experimental Medicine 210 (13), 2939-2950, 2013
Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
PG Fallon, SJ Ballantyne, NE Mangan, JL Barlow, A Dasvarma, ...
Journal of Experimental Medicine 203 (4), 1105-1116, 2006
The alarmin IL-33 promotes regulatory T-cell function in the intestine
C Schiering, T Krausgruber, A Chomka, A Fröhlich, K Adelmann, ...
Nature 513 (7519), 564-568, 2014
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ...
Nature 556 (7699), 113-117, 2018
MHCII-mediated dialog between group 2 innate lymphoid cells and CD4+ T cells potentiates type 2 immunity and promotes parasitic helminth expulsion
CJ Oliphant, YY Hwang, JA Walker, M Salimi, SH Wong, JM Brewer, ...
Immunity 41 (2), 283-295, 2014
Transcription factor RORα is critical for nuocyte development
SH Wong, JA Walker, HE Jolin, LF Drynan, E Hams, A Camelo, JL Barlow, ...
Nature immunology 13 (3), 229-236, 2012
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
MJ Townsend, PG Fallon, DJ Matthews, HE Jolin, ANJ McKenzie
Journal of experimental medicine 191 (6), 1069-1076, 2000
Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific.
PG Fallon, MJ Doenhoff
The American journal of tropical medicine and hygiene 51 (1), 83-88, 1994
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent
PG Fallon, EJ Richardson, GJ McKenzie, ANJ McKenzie
The Journal of Immunology 164 (5), 2585-2591, 2000
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming
PG Fallon, T Sasaki, A Sandilands, LE Campbell, SP Saunders, ...
Nature genetics 41 (5), 602-608, 2009
Impaired development of Th2 cells in IL-13-deficient mice
GJ McKenzie, CL Emson, SE Bell, S Anderson, P Fallon, G Zurawski, ...
Immunity 9 (3), 423-432, 1998
Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model
S Amu, SP Saunders, M Kronenberg, NE Mangan, A Atzberger, PG Fallon
Journal of Allergy and Clinical Immunology 125 (5), 1114-1124. e8, 2010
The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis
EP Cummins, F Seeballuck, SJ Keely, NE Mangan, JJ Callanan, ...
Gastroenterology 134 (1), 156-165. e1, 2008
Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2–mediated responses
GJ McKenzie, PG Fallon, CL Emson, RK Grencis, ANJ McKenzie
The Journal of experimental medicine 189 (10), 1565-1572, 1999
The alarmin interleukin-33 drives protective antiviral CD8+ T cell responses
WV Bonilla, A Fröhlich, K Senn, S Kallert, M Fernandez, S Johnson, ...
Science 335 (6071), 984-989, 2012
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13
PG Fallon, HE Jolin, P Smith, CL Emson, MJ Townsend, R Fallon, P Smith, ...
Immunity 17 (1), 7-17, 2002
IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
MJ Townsend, PG Fallon, DJ Matthews, P Smith, HE Jolin, ANJ McKenzie
Immunity 13 (4), 573-583, 2000
Helminth infection protects mice from anaphylaxis via IL-10-producing B cells
NE Mangan, RE Fallon, P Smith, N van Rooijen, AN McKenzie, PG Fallon
The Journal of Immunology 173 (10), 6346-6356, 2004
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis
E Hams, ME Armstrong, JL Barlow, SP Saunders, C Schwartz, G Cooke, ...
Proceedings of the National Academy of Sciences 111 (1), 367-372, 2014
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