| Evolution of hormone-receptor complexity by molecular exploitation JT Bridgham, SM Carroll, JW Thornton Science 312 (5770), 97-101, 2006 | 688 | 2006 |
| Crystal structure of an ancient protein: evolution by conformational epistasis EA Ortlund, JT Bridgham, MR Redinbo, JW Thornton Science 317 (5844), 1544-1548, 2007 | 498 | 2007 |
| An epistatic ratchet constrains the direction of glucocorticoid receptor evolution JT Bridgham, EA Ortlund, JW Thornton Nature 461 (7263), 515-519, 2009 | 447 | 2009 |
| The FET4 gene encodes the low affinity Fe (II) transport protein of Saccharomyces cerevisiae DR Dix, JT Bridgham, MA Broderius, CA Byersdorfer, DJ Eide Journal of Biological Chemistry 269 (42), 26092-26099, 1994 | 390 | 1994 |
| Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor JT Bridgham, GN Eick, C Larroux, K Deshpande, MJ Harms, ... PLoS biology 8 (10), e1000497, 2010 | 257 | 2010 |
| The Octopus vulgaris Estrogen Receptor Is a Constitutive Transcriptional Activator: Evolutionary and Functional Implications J Keay, JT Bridgham, JW Thornton Endocrinology 147 (8), 3861-3869, 2006 | 227 | 2006 |
| Characterization of the FET4 protein of yeast: evidence for a direct role in the transport of iron D Dix, J Bridgham, M Broderius, D Eide Journal of Biological Chemistry 272 (18), 11770-11777, 1997 | 173 | 1997 |
| Characterization of the chicken follicle-stimulating hormone receptor (cFSH-R) complementary deoxyribonucleic acid, and expression of cFSH-R messenger ribonucleic acid in the ovary S You, JT Bridgham, DN Foster, AL Johnson Biology of reproduction 55 (5), 1055-1062, 1996 | 152 | 1996 |
| Susceptibility of avian ovarian granulosa cells to apoptosis is dependent upon stage of follicle development and is related to endogenous levels of bcl-xlong gene expression AL Johnson, JT Bridgham, JP Witty, JL Tilly Endocrinology 137 (5), 2059-2066, 1996 | 151 | 1996 |
| Conservation of steroidogenic acute regulatory (StAR) protein structure and expression in vertebrates MP Bauer, JT Bridgham, DM Langenau, AL Johnson, FW Goetz Molecular and cellular endocrinology 168 (1-2), 119-125, 2000 | 149 | 2000 |
| Caspase-mediated apoptosis in the vertebrate ovary AL Johnson, JT Bridgham REPRODUCTION-CAMBRIDGE- 124 (1), 19-27, 2002 | 148 | 2002 |
| Evolution of a new function by degenerative mutation in cephalochordate steroid receptors JT Bridgham, JE Brown, A Rodríguez-Marí, JM Catchen, JW Thornton PLoS genetics 4 (9), e1000191, 2008 | 141 | 2008 |
| Regulation of steroidogenic acute regulatory protein and luteinizing hormone receptor messenger ribonucleic acid in hen granulosa cells AL Johnson, JT Bridgham Endocrinology 142 (7), 3116-3124, 2001 | 130 | 2001 |
| The vacuolar H+-ATPase of Saccharomyces cerevisiae is required for efficient copper detoxification, mitochondrial function, and iron metabolism DJ Eide, JT Bridgham, Z Zhao, JR Mattoon Molecular and General Genetics MGG 241, 447-456, 1993 | 129 | 1993 |
| Activation of the Akt/protein kinase B signaling pathway is associated with granulosa cell survival AL Johnson, JT Bridgham, JA Swenson Biology of Reproduction 64 (5), 1566-1574, 2001 | 128 | 2001 |
| Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module AN McKeown, JT Bridgham, DW Anderson, MN Murphy, EA Ortlund, ... Cell 159 (1), 58-68, 2014 | 122 | 2014 |
| Relationship between steroidogenic acute regulatory protein expression and progesterone production in hen granulosa cells during follicle development AL Johnson, EV Solovieva, JT Bridgham Biology of reproduction 67 (4), 1313-1320, 2002 | 120 | 2002 |
| Induction of apoptotic cell death in hen granulosa cells by ceramide JP Witty, JT Bridgham, AL Johnson Endocrinology 137 (12), 5269-5277, 1996 | 120 | 1996 |
| Characterization of a chicken luteinizing hormone receptor (cLH-R) complementary deoxyribonucleic acid, and expression of cLH-R messenger ribonucleic acid in the ovary AL Johnson, JT Bridgham, B Wagner Biology of reproduction 55 (2), 304-309, 1996 | 116 | 1996 |
| Robustness of reconstructed ancestral protein functions to statistical uncertainty GN Eick, JT Bridgham, DP Anderson, MJ Harms, JW Thornton Molecular biology and evolution 34 (2), 247-261, 2016 | 106 | 2016 |
