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Charles Gauthier
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Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane-and oleanane-type saponins
C Gauthier, J Legault, K Girard-Lalancette, V Mshvildadze, A Pichette
Bioorganic & Medicinal Chemistry 17 (5), 2002-2008, 2009
2422009
Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents
C Gauthier, J Legault, M Lebrun, P Dufour, A Pichette
Bioorganic & Medicinal Chemistry 14 (19), 6713-6725, 2006
1922006
Synthesis and structure–activity relationship study of cytotoxic germanicane-and lupane-type 3β-O-monodesmosidic saponins starting from betulin
D Thibeault, C Gauthier, J Legault, J Bouchard, P Dufour, A Pichette
Bioorganic & Medicinal Chemistry 15 (18), 6144-6157, 2007
1382007
Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins
C Gauthier, J Legault, S Lavoie, S Rondeau, S Tremblay, A Pichette
Journal of Natural Products 72 (1), 72-81, 2009
1132009
Advances in the synthesis and pharmacological activity of lupane-type triterpenoid saponins
C Gauthier, J Legault, M Piochon-Gauthier, A Pichette
Phytochemistry Reviews 10, 521-544, 2011
762011
Anticancer diarylheptanoid glycosides from the inner bark of Betula papyrifera
V Mshvildadze, J Legault, S Lavoie, C Gauthier, A Pichette
Phytochemistry 68 (20), 2531-2536, 2007
672007
Synthesis of betulinic acid acyl glucuronide for application in anticancer prodrug monotherapy
C Gauthier, J Legault, S Rondeau, A Pichette
Tetrahedron Letters 50 (9), 988-991, 2009
622009
Synthesis of two natural betulinic acid saponins containing α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranose and their analogues
C Gauthier, J Legault, S Lavoie, S Rondeau, S Tremblay, A Pichette
Tetrahedron 64 (30-31), 7386-7399, 2008
622008
Synthesis and cytotoxicity evaluation of natural α-bisabolol β-D-fucopyranoside and analogues
M Piochon, J Legault, C Gauthier, A Pichette
Phytochemistry 70 (2), 228-236, 2009
552009
Recent progress in the synthesis of naturally occurring triterpenoid saponins
C Gauthier, J Legault, A Pichette
Mini-Reviews in Organic Chemistry 6 (4), 321, 2009
502009
Chemical composition and anti-herpes simplex virus type 1 (HSV-1) activity of extracts from Cornus canadensis
S Lavoie, I Côté, A Pichette, C Gauthier, M Ouellet, F Nagau-Lavoie, ...
BMC Complementary and Alternative Medicine 17 (1), 123, 2017
482017
Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products
C Gauthier, J Legault, M Piochon, S Lavoie, S Tremblay, A Pichette
Bioorganic & Medicinal Chemistry Letters 19 (8), 2310-2314, 2009
472009
Burkholderia pseudomallei capsular polysaccharide recognition by a monoclonal antibody reveals key details toward a biodefense vaccine and diagnostics against melioidosis
R Marchetti, MJ Dillon, MN Burtnick, MA Hubbard, M Tamigney Kenfack, ...
ACS Chemical Biology, 2015
452015
Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
M Tamigney Kenfack, M Mazur, T Nualnoi, TL Shaffer, A Ngassimou, ...
Nature Communications 8 (1), 1-13, 2017
392017
Abibalsamins A and B, two new tetraterpenoids from Abies balsamea oleoresin
S Lavoie, J Legault, C Gauthier, V Mshvildadze, S Mercier, A Pichette
Organic Letters 14 (6), 1504-1507, 2012
372012
Synthesis of 1,2-cis-homoiminosugars derived from GlcNAc and GalNAc exploiting a β-amino alcohol skeletal rearrangement
Y Blériot, N Auberger, Y Jagadeesh, C Gauthier, G Prencipe, AT Tran, ...
Organic Letters 16 (21), 5512-5515, 2014
362014
Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity
C Gauthier, P Chassagne, FX Theillet, C Guerreiro, F Thouron, F Nato, ...
Organic & Biomolecular Chemistry 12 (24), 4218-4232, 2014
362014
Modulation of bacterial multicellularity via spatio-specific polysaccharide secretion
ST Islam, I Vergara Alvarez, F Saïdi, A Giuseppi, E Vinogradov, G Sharma, ...
PLoS Biology 18 (6), e3000728, 2020
352020
Polysaccharides from Burkholderia species as targets for vaccine development, immunomodulation and chemical synthesis
M Cloutier, K Muru, G Ravicoularamin, C Gauthier
Natural Product Reports 35 (12), 1251-1293, 2018
312018
Intramolecular aglycon delivery enables the synthesis of 6-deoxy-beta-D-manno-heptosides as fragments of Burkholderia pseudomallei and Burkholderia mallei capsular polysaccharide
M Tamigney Kenfack, Y Bleriot, C Gauthier
The Journal of Organic Chemistry 79 (10), 4615-4634, 2014
312014
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