| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 11048* | 2016 |
| Chemical manipulation of hsp70 ATPase activity regulates tau stability UK Jinwal, Y Miyata, J Koren, JR Jones, JH Trotter, L Chang, J O'Leary, ... Journal of Neuroscience 29 (39), 12079-12088, 2009 | 272 | 2009 |
| Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ... The Journal of Neuroscience 33 (22), 9498-9507, 2013 | 261 | 2013 |
| Akt and CHIP coregulate tau degradation through coordinated interactions CA Dickey, J Koren, YJ Zhang, Y Xu, UK Jinwal, MJ Birnbaum, B Monks, ... Proceedings of the National Academy of Sciences 105 (9), 3622-3627, 2008 | 244 | 2008 |
| The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ... The Journal of Neuroscience 30 (2), 591-599, 2010 | 228 | 2010 |
| Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones A Rousaki, Y Miyata, UK Jinwal, CA Dickey, JE Gestwicki, ERP Zuiderweg Journal of molecular biology 411 (3), 614-632, 2011 | 204 | 2011 |
| Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ... Molecular neurodegeneration 5 (1), 45, 2010 | 201 | 2010 |
| 1, 25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498 R Kasiappan, Z Shen, KW Anfernee, U Jinwal, J Tang, P Lungchukiet, ... Journal of Biological Chemistry 287 (49), 41297-41309, 2012 | 148 | 2012 |
| Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice L Lebson, K Nash, S Kamath, D Herber, N Carty, DC Lee, Q Li, ... The Journal of Neuroscience 30 (29), 9651-9658, 2010 | 146 | 2010 |
| Chaperone signalling complexes in Alzheimer's disease J Koren, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ... Journal of cellular and molecular medicine 13 (4), 619-630, 2009 | 144 | 2009 |
| A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51 JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ... PloS one 6 (9), e24840, 2011 | 134 | 2011 |
| Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ... The Journal of Neuroscience 30 (46), 15374-15382, 2010 | 133 | 2010 |
| Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels Y Miyata, X Li, HF Lee, UK Jinwal, SR Srinivasan, SP Seguin, ZT Young, ... ACS chemical neuroscience 4 (6), 930-939, 2013 | 131 | 2013 |
| Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ... Biological psychiatry 74 (5), 367-374, 2013 | 125 | 2013 |
| Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome JL Daily, K Nash, U Jinwal, T Golde, J Rogers, MM Peters, RD Burdine, ... PloS one 6 (12), e27221, 2011 | 125 | 2011 |
| Imbalance of Hsp70 family variants fosters tau accumulation UK Jinwal, E Akoury, JF Abisambra, JC O'Leary, AD Thompson, LJ Blair, ... The FASEB Journal 27 (4), 1450-1459, 2013 | 122 | 2013 |
| Natural products as a rich source of tau-targeting drugs for Alzheimer's disease L Calcul, B Zhang, UK Jinwal, CA Dickey, BJ Baker Future medicinal chemistry 4 (13), 1751-1761, 2012 | 120 | 2012 |
| Hsc70 rapidly engages tau after microtubule destabilization UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ... Journal of Biological Chemistry 285 (22), 16798-16805, 2010 | 102 | 2010 |
| Facilitating Akt clearance via manipulation of Hsp70 activity and levels J Koren, UK Jinwal, Y Jin, J O'Leary, JR Jones, AG Johnson, LJ Blair, ... Journal of Biological Chemistry 285 (4), 2498-2505, 2010 | 98 | 2010 |
| Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70 Y Miyata, JN Rauch, UK Jinwal, AD Thompson, S Srinivasan, CA Dickey, ... Chemistry & biology 19 (11), 1391-1399, 2012 | 97 | 2012 |
