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Lucas Cezar Pinheiro
Lucas Cezar Pinheiro
Professor Departamento de Farmacologia UFSC
Adresse e-mail validée de ufsc.br
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Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension
MF Montenegro, JH Amaral, LC Pinheiro, EK Sakamoto, GC Ferreira, ...
Free Radical Biology and Medicine 51 (1), 144-152, 2011
1482011
Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension
LC Pinheiro, JH Amaral, GC Ferreira, RL Portella, CS Ceron, ...
Free Radical Biology and Medicine 87, 252-262, 2015
932015
Increase in gastric pH reduces hypotensive effect of oral sodium nitrite in rats
LC Pinheiro, MF Montenegro, JH Amaral, GC Ferreira, AM Oliveira, ...
Free Radical Biology and Medicine 53 (4), 701-709, 2012
892012
Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension
JH Amaral, GC Ferreira, LC Pinheiro, MF Montenegro, JE Tanus-Santos
Redox biology 5, 340-346, 2015
652015
The potential of stimulating nitric oxide formation in the treatment of hypertension
LC Pinheiro, JE Tanus-Santos, MM Castro
Expert opinion on therapeutic targets 21 (5), 543-556, 2017
532017
Antihypertensive and antioxidant effects of a single daily dose of sodium nitrite in a model of renovascular hypertension
MF Montenegro, LC Pinheiro, JH Amaral, DMO Marçal, ACT Palei, ...
Naunyn-Schmiedeberg's archives of pharmacology 385, 509-517, 2012
512012
TEMPOL enhances the antihypertensive effects of sodium nitrite by mechanisms facilitating nitrite-derived gastric nitric oxide formation
JH Amaral, MF Montenegro, LC Pinheiro, GC Ferreira, RP Barroso, ...
Free Radical Biology and Medicine 65, 446-455, 2013
492013
Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction
LC Pinheiro, GH Oliveira-Paula, RL Portella, DA Guimarães, ...
Redox biology 9, 134-143, 2016
472016
β1-Adrenergic blockers exert antioxidant effects, reduce matrix metalloproteinase activity, and improve renovascular hypertension-induced cardiac hypertrophy
E Rizzi, DA Guimaraes, CS Ceron, CM Prado, LC Pinheiro, ...
Free Radical Biology and Medicine 73, 308-317, 2014
472014
Vascular xanthine oxidoreductase contributes to the antihypertensive effects of sodium nitrite in l-NAME hypertension
MF Montenegro, LC Pinheiro, JH Amaral, GC Ferreira, RL Portella, ...
Naunyn-Schmiedeberg's archives of pharmacology 387, 591-598, 2014
462014
Antihypertensive effects of inducible nitric oxide synthase inhibition in experimental pre‐eclampsia
LM Amaral, LC Pinheiro, DA Guimaraes, ACT Palei, JT Sertório, ...
Journal of cellular and molecular medicine 17 (10), 1300-1307, 2013
462013
Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension
DA Guimarães, E Rizzi, CS Ceron, LC Pinheiro, RF Gerlach, ...
Redox Biology 1 (1), 578-585, 2013
442013
Sources and effects of oxidative stress in hypertension
LC Pinheiro, GH Oliveira-Paula
Current hypertension reviews 16 (3), 166-180, 2020
422020
Mechanisms impairing blood pressure responses to nitrite and nitrate
GH Oliveira-Paula, LC Pinheiro, JE Tanus-Santos
Nitric Oxide 85, 35-43, 2019
422019
Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect
LC Pinheiro, GC Ferreira, JH Amaral, RL Portella, S de OC Tella, ...
Free Radical Biology and Medicine 101, 226-235, 2016
372016
Antioxidant and antihypertensive responses to oral nitrite involves activation of the Nrf2 pathway
JH Amaral, ES Rizzi, R Alves-Lopes, LC Pinheiro, RC Tostes, ...
Free Radical Biology and Medicine 141, 261-268, 2019
362019
Chromosome numbers and DNA C values in the genus Lippia (Verbenaceae)
JMS de Campos, SM Sousa, PS Silva, LC Pinheiro, F Sampaio, LF Viccini
Plant Systematics and Evolution 291, 133-140, 2011
332011
Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects
E Rizzi, JH Amaral, DA Guimaraes, SO Conde-Tella, LC Pinheiro, ...
Free Radical Biology and Medicine 130, 234-243, 2019
302019
Nitrite exerts antioxidant effects, inhibits the mTOR pathway and reverses hypertension-induced cardiac hypertrophy
DA Guimaraes, MA Dos Passos, E Rizzi, LC Pinheiro, JH Amaral, ...
Free Radical Biology and Medicine 120, 25-32, 2018
302018
Nitrate decreases xanthine oxidoreductase-mediated nitrite reductase activity and attenuates vascular and blood pressure responses to nitrite
C Damacena-Angelis, GH Oliveira-Paula, LC Pinheiro, EJ Crevelin, ...
Redox biology 12, 291-299, 2017
302017
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