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Michael Emanuele
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A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
J Luo, MJ Emanuele, D Li, CJ Creighton, MR Schlabach, TF Westbrook, ...
Cell 137 (5), 835-848, 2009
11552009
Global identification of modular cullin-RING ligase substrates
MJ Emanuele, AEH Elia, Q Xu, CR Thoma, L Izhar, Y Leng, A Guo, ...
Cell 147 (2), 459-474, 2011
4512011
Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome
HW Wang, ME Putt, MJ Emanuele, DB Shin, E Glatstein, AG Yodh, ...
Cancer research 64 (20), 7553-7561, 2004
2092004
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly
MJ Emanuele, W Lan, M Jwa, SA Miller, CSM Chan, PT Stukenberg
The Journal of cell biology 181 (2), 241-254, 2008
1892008
A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells
T Ly, Y Ahmad, A Shlien, D Soroka, A Mills, MJ Emanuele, MR Stratton, ...
Elife 3, e01630, 2014
1402014
Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate
MJ Emanuele, A Ciccia, AEH Elia, SJ Elledge
Proceedings of the National Academy of Sciences 108 (24), 9845-9850, 2011
1192011
Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore
MJ Emanuele, ML McCleland, DL Satinover, PT Stukenberg
Molecular biology of the cell 16 (10), 4882-4892, 2005
912005
APC/C and SCFcyclin F constitute a reciprocal feedback circuit controlling S-phase entry
R Choudhury, T Bonacci, A Arceci, D Lahiri, CA Mills, JL Kernan, ...
Cell reports 16 (12), 3359-3372, 2016
862016
Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin
VV Vorozhko, MJ Emanuele, MJ Kallio, PT Stukenberg, GJ Gorbsky
Chromosoma 117, 169-179, 2008
802008
Dissenting degradation: Deubiquitinases in cell cycle and cancer
T Bonacci, MJ Emanuele
Seminars in cancer biology 67, 145-158, 2020
792020
FOXM1 deubiquitination by USP21 regulates cell cycle progression and paclitaxel sensitivity in basal-like breast cancer
A Arceci, T Bonacci, X Wang, K Stewart, JS Damrauer, KA Hoadley, ...
Cell reports 26 (11), 3076-3086. e6, 2019
722019
Who guards the guardian? Mechanisms that restrain APC/C during the cell cycle
J Kernan, T Bonacci, MJ Emanuele
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (12), 1924-1933, 2018
702018
Cezanne/OTUD 7B is a cell cycle‐regulated deubiquitinase that antagonizes the degradation of APC/C substrates
T Bonacci, A Suzuki, GD Grant, N Stanley, JG Cook, NG Brown, ...
The EMBO journal 37 (16), e98701, 2018
702018
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients
TM Busch, SM Hahn, EP Wileyto, CJ Koch, DL Fraker, P Zhang, M Putt, ...
Clinical cancer research 10 (14), 4630-4638, 2004
702004
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells
MT Weng, JH Lee, SC Wei, Q Li, S Shahamatdar, D Hsu, AJ Schetter, ...
Proceedings of the National Academy of Sciences 109 (52), E3659-E3667, 2012
692012
The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome
JY Jason, SR Paranjape, MP Walker, R Choudhury, JM Wolter, G Fragola, ...
Journal of Biological Chemistry 292 (30), 12503-12515, 2017
682017
Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment
MJ Emanuele, PT Stukenberg
Cell 130 (5), 893-905, 2007
572007
Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer
DR Blake, AV Vaseva, RG Hodge, MKP Kline, TSK Gilbert, V Tyagi, ...
Science signaling 12 (590), eaav7259, 2019
542019
Complex cartography: regulation of E2F transcription factors by cyclin F and ubiquitin
MJ Emanuele, TP Enrico, RD Mouery, D Wasserman, S Nachum, A Tzur
Trends in cell biology 30 (8), 640-652, 2020
502020
Chlamydia trachomatis-induced alterations in the host cell proteome are required for intracellular growth
AJ Olive, MG Haff, MJ Emanuele, LM Sack, JR Barker, SJ Elledge, ...
Cell host & microbe 15 (1), 113-124, 2014
482014
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