MEK/ERK signaling pathway regulates the expression of Bcl‐2, Bcl‐XL, and Mcl‐1 and promotes survival of human pancreatic cancer cells MJ Boucher, J Morisset, PH Vachon, JC Reed, J Lainé, N Rivard Journal of cellular biochemistry 79 (3), 355-369, 2000 | 515 | 2000 |
Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts N Rivard, G L'Allemain, J Bartek, J Pouysségur Journal of Biological Chemistry 271 (31), 18337-18341, 1996 | 305 | 1996 |
Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage BA Auclair, YD Benoit, N Rivard, Y Mishina, N Perreault Gastroenterology 133 (3), 887-896, 2007 | 226 | 2007 |
Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation P Laprise, P Chailler, M Houde, JF Beaulieu, MJ Boucher, N Rivard Journal of biological chemistry 277 (10), 8226-8234, 2002 | 205 | 2002 |
Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2 M Houde, P Laprise, D Jean, M Blais, C Asselin, N Rivard Journal of Biological Chemistry 276 (24), 21885-21894, 2001 | 193 | 2001 |
Expression of endomembrane calcium pumps in colon and gastric cancer cells: induction of SERCA3 expression during differentiation P Gélébart, T Kovács, JP Brouland, R van Gorp, J Grossmann, N Rivard, ... Journal of Biological Chemistry 277 (29), 26310-26320, 2002 | 182 | 2002 |
Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells JC Aliaga, C Deschênes, JF Beaulieu, EL Calvo, N Rivard American Journal of Physiology-Gastrointestinal and Liver Physiology 277 (3 …, 1999 | 178 | 1999 |
Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer E Lemieux, S Cagnol, K Beaudry, J Carrier, N Rivard Oncogene 34 (38), 4914-4927, 2015 | 166 | 2015 |
Polymeric binders suppress gliadin-induced toxicity in the intestinal epithelium M Pinier, EF Verdu, M Nasser–Eddine, CS David, A Vézina, N Rivard, ... Gastroenterology 136 (1), 288-298, 2009 | 163 | 2009 |
Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells P Laprise, A Viel, N Rivard Journal of Biological Chemistry 279 (11), 10157-10166, 2004 | 160 | 2004 |
Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor β1-induced furin gene transactivation F Blanchette, N Rivard, P Rudd, F Grondin, L Attisano, CM Dubois Journal of Biological Chemistry 276 (36), 33986-33994, 2001 | 152 | 2001 |
A temporal and biochemical link between growth factor-activated MAP kinases, cyclin D1 induction and cell cycle entry JN Lavoie, N Rivard, G L’Allemain, J Pouysségur Progress in cell cycle research, 49-58, 1996 | 149 | 1996 |
Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis B Bian, S Mongrain, S Cagnol, MJ Langlois, J Boulanger, G Bernatchez, ... Molecular carcinogenesis 55 (5), 671-687, 2016 | 144 | 2016 |
MAP kinase cascade is required for p27 downregulation and S phase entry in fibroblasts and epithelial cells N Rivard, MJ Boucher, C Asselin, G L’Allemain American Journal of Physiology-Cell Physiology 277 (4), C652-C664, 1999 | 134 | 1999 |
Down‐regulation of MEK/ERK signaling by E‐cadherin‐dependent PI3K/Akt pathway in differentiating intestinal epithelial cells P Laprise, MJ Langlois, MJ Boucher, C Jobin, N Rivard Journal of cellular physiology 199 (1), 32-39, 2004 | 120 | 2004 |
Signals from the AT2 (Angiotensin Type 2) Receptor of Angiotensin II Inhibit p21ras and Activate MAPK (Mitogen-Activated Protein Kinase) to Induce … L Gendron∗, L Laflamme∗, N Rivard, C Asselin, MD Payet, N Gallo-Payet Molecular endocrinology 13 (9), 1615-1626, 1999 | 120 | 1999 |
The phosphotyrosine phosphatase PTP1D, but not PTP1C, is an essential mediator of fibroblast proliferation induced by tyrosine kinase and G protein-coupled receptors N Rivard, FR McKenzie, JM Brondello, J Pouysségur Journal of Biological Chemistry 270 (18), 11017-11024, 1995 | 118 | 1995 |
Role of p27Kip1 in human intestinal cell differentiation C Deschênes, A Vézina, JF Beaulieu, N Rivard Gastroenterology 120 (2), 423-438, 2001 | 113 | 2001 |
Constitutively active MEK1 is sufficient to induce epithelial‐to‐mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis É Lemieux, S Bergeron, V Durand, C Asselin, C Saucier, N Rivard International journal of cancer 125 (7), 1575-1586, 2009 | 110 | 2009 |
Oncogenic KRAS and BRAF activation of the MEK/ERK signaling pathway promotes expression of dual-specificity phosphatase 4 (DUSP4/MKP2) resulting in nuclear ERK1/2 inhibition S Cagnol, N Rivard Oncogene 32 (5), 564-576, 2013 | 107 | 2013 |