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Pierre-Axel Monternier
Pierre-Axel Monternier
Poxel SA
Adresse e-mail validée de poxelpharma.com
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Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions
HS Wong, PA Dighe, V Mezera, PA Monternier, MD Brand
Journal of Biological Chemistry 292 (41), 16804-16809, 2017
4222017
Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice
B Benoit, E Meugnier, M Castelli, S Chanon, A Vieille-Marchiset, ...
Nature medicine 23 (8), 990-996, 2017
1742017
Mitochondrial phenotypic flexibility enhances energy savings during winter fast in king penguin chicks
PA Monternier, V Marmillot, JL Rouanet, D Roussel
Journal of Experimental Biology 217 (15), 2691-2697, 2014
552014
Direct AMPK activation corrects NASH in rodents through metabolic effects and direct action on inflammation and fibrogenesis
P Gluais‐Dagorn, M Foretz, GR Steinberg, B Batchuluun, ...
Hepatology Communications 6 (1), 101-119, 2022
372022
S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site IQ without inhibiting reverse electron flow through Complex I
HS Wong, PA Monternier, MD Brand
Free Radical Biology and Medicine 143, 545-559, 2019
322019
Reduced lactic acidosis risk with Imeglimin: Comparison with Metformin
P Theurey, G Vial, E Fontaine, P Monternier, P Fouqueray, S Bolze, ...
Physiological reports 10 (5), e15151, 2022
192022
Hormetic response triggers multifaceted anti-oxidant strategies in immature king penguins (Aptenodytes patagonicus)
B Rey, C Dégletagne, J Bodennec, PA Monternier, M Mortz, D Roussel, ...
Free Radical Biology and Medicine 97, 577-587, 2016
192016
Skeletal muscle phenotype affects fasting-induced mitochondrial oxidative phosphorylation flexibility in cold-acclimated ducklings
PA Monternier, A Fongy, F Hervant, J Drai, D Collin-Chavagnac, ...
The Journal of Experimental Biology 218 (15), 2427-2434, 2015
172015
Mitochondrial oxidative phosphorylation efficiency is upregulated during fasting in two major oxidative tissues of ducklings
PA Monternier, L Teulier, J Drai, A Bourguignon, D Collin-Chavagnac, ...
Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2017
152017
Skeletal muscle metabolism in sea-acclimatized king penguins. II. Improved efficiency of mitochondrial bioenergetics
D Roussel, V Marmillot, PA Monternier, A Bourguignon, G Toullec, ...
Journal of Experimental Biology 223 (21), jeb233684, 2020
132020
Plate-based measurement of superoxide and hydrogen peroxide production by isolated mitochondria
HS Wong, PA Monternier, AL Orr, MD Brand
Mitochondrial Bioenergetics: Methods and Protocols, 287-299, 2018
102018
Lipid-induced thermogenesis is up-regulated by the first cold-water immersions in juvenile penguins
L Teulier, B Rey, J Tornos, M Le Coadic, PA Monternier, A Bourguignon, ...
Journal of Comparative Physiology B 186, 639-650, 2016
82016
Therapeutic potential of deuterium‐stabilized (R)‐pioglitazone—PXL065—for X‐linked adrenoleukodystrophy
PA Monternier, J Singh, P Parasar, P Theurey, S DeWitt, V Jacques, ...
Journal of inherited metabolic disease 45 (4), 832-847, 2022
52022
Beneficial effects of the direct AMP-kinase activator PXL770 in in vitro and in vivo models of X-linked adrenoleukodystrophy
PA Monternier, P Parasar, P Theurey, PG Dagorn, N Kaur, TN Nagaraja, ...
Journal of Pharmacology and Experimental Therapeutics 382 (2), 208-222, 2022
32022
P4607 A specific complex I-induced ROS modulator, OP2113, is a new cardioproctective agent against acute myocardial infarction injuries during reperfusion
A Boucard, F Marin, PA Monternier, M Brand, B Le Grand
European Heart Journal 40 (Supplement_1), ehz745. 0990, 2019
22019
A specific complex I-induced ROS modulator, OP2113, is a new cardioproctective agent against acute myocardial infarction injuries during reperfusion
A Boucard, F Marin, PA Monternier, M Brand, B Le Grand
EUROPEAN HEART JOURNAL 40, 2818-2818, 2019
12019
Deuterium-Stabilized (R)-Pioglitazone, PXL065, for Treatment of X-Linked Adrenoleukodystrophy (ALD)
P Monternier, J Singh, S DeWitt, P Gluais, DE Moller, S Hallakou-Bozec
2022
Validation of direct AMP kinase (AMPK) activation for treatment of X-linked Adrenoleukodystrophy
PA Monternier, J Singh, P Gluais, D Moller, S Bozec
Journal of the Neurological Sciences 429, 2021
2021
PXL770, A NEW DIRECT AMP KINASE ACTIVATOR AND POTENTIAL NASH THERAPEUTIC, PRODUCES ANTI-INFLAMMATORY EFFECTS IN MOUSE LIVER AND ADIPOSE TISSUE AND IN HUMAN IMMUNE CELLS
P Gluais-Dagorn, PA Monternier, B Guigas, S Bolze, DE Moller, S Bozec
The Liver Meeting Digital Experience™, 2020
2020
PXL770, A NOVEL DIRECT AMP-ACTIVATED PROTEIN KINASE ACTIVATOR PRODUCES GREATER EFFICACY WHEN COMBINED WITH OTHER KEY THERAPEUTIC MECHANISMS TARGETING NASH
PA Monternier, P Gluais-Dagorn, S Bolze, L Thisted, M Feigh, DE Moller, ...
The Liver Meeting Digital Experience™, 2020
2020
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