CRISPR provides acquired resistance against viruses in prokaryotes R Barrangou, C Fremaux, H Deveau, M Richards, P Boyaval, S Moineau, ... Science 315 (5819), 1709-1712, 2007 | 8164 | 2007 |
Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria G Gasiunas, R Barrangou, P Horvath, V Siksnys Proceedings of the National Academy of Sciences 109 (39), E2579-E2586, 2012 | 4000 | 2012 |
Evolution and classification of the CRISPR–Cas systems KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ... Nature Reviews Microbiology 9 (6), 467-477, 2011 | 3495 | 2011 |
CRISPR/Cas, the immune system of bacteria and archaea P Horvath, R Barrangou Science 327 (5962), 167-170, 2010 | 3374 | 2010 |
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA JE Garneau, MÈ Dupuis, M Villion, DA Romero, R Barrangou, P Boyaval, ... Nature 468 (7320), 67-71, 2010 | 3373 | 2010 |
An updated evolutionary classification of CRISPR–Cas systems KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ... Nature reviews microbiology 13 (11), 722-736, 2015 | 3030 | 2015 |
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020 | 2105 | 2020 |
Phage Response to CRISPR-Encoded Resistance in Streptococcus thermophilus H Deveau, R Barrangou, JE Garneau, J Labonté, C Fremaux, P Boyaval, ... Journal of bacteriology 190 (4), 1390-1400, 2008 | 1859 | 2008 |
Comparative genomics of the lactic acid bacteria K Makarova, A Slesarev, Y Wolf, A Sorokin, B Mirkin, E Koonin, A Pavlov, ... Proceedings of the National Academy of Sciences 103 (42), 15611-15616, 2006 | 1730 | 2006 |
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli R Sapranauskas, G Gasiunas, C Fremaux, R Barrangou, P Horvath, ... Nucleic acids research 39 (21), 9275-9282, 2011 | 1546 | 2011 |
CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation D Bhaya, M Davison, R Barrangou Annual review of genetics 45 (1), 273-297, 2011 | 1524 | 2011 |
Applications of CRISPR technologies in research and beyond R Barrangou, JA Doudna Nature biotechnology 34 (9), 933-941, 2016 | 1091 | 2016 |
Diversity, Activity, and Evolution of CRISPR Loci in Streptococcus thermophilus P Horvath, DA Romero, AC Coûté-Monvoisin, M Richards, H Deveau, ... Journal of bacteriology 190 (4), 1401-1412, 2008 | 1086 | 2008 |
CRISPR-Cas systems: prokaryotes upgrade to adaptive immunity R Barrangou, LA Marraffini Molecular cell 54 (2), 234-244, 2014 | 1078 | 2014 |
Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM E Altermann, WM Russell, MA Azcarate-Peril, R Barrangou, BL Buck, ... Proceedings of the National Academy of Sciences 102 (11), 3906-3912, 2005 | 782 | 2005 |
The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533 RD Pridmore, B Berger, F Desiere, D Vilanova, C Barretto, AC Pittet, ... Proceedings of the National Academy of Sciences 101 (8), 2512-2517, 2004 | 625 | 2004 |
Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system T Sinkunas, G Gasiunas, C Fremaux, R Barrangou, P Horvath, V Siksnys The EMBO journal 30 (7), 1335-1342, 2011 | 619 | 2011 |
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera Z Sun, HMB Harris, A McCann, C Guo, S Argimón, W Zhang, X Yang, ... Nature communications 6 (1), 8322, 2015 | 607 | 2015 |
Programmable removal of bacterial strains by use of genome-targeting CRISPR-Cas systems AA Gomaa, HE Klumpe, ML Luo, K Selle, R Barrangou, CL Beisel MBio 5 (1), 10.1128/mbio. 00928-13, 2014 | 499 | 2014 |
Guide RNA functional modules direct Cas9 activity and orthogonality AE Briner, PD Donohoue, AA Gomaa, K Selle, EM Slorach, CH Nye, ... Molecular cell 56 (2), 333-339, 2014 | 395 | 2014 |